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Here, the authors discuss how spatial metabolomics could contribute to better understanding of cellular mechanisms in kidney health and disease, as well as the discovery of blood and urine biomarkers and drug targets for new therapies to halt kidney disease progression.
In this Perspective article, the authors argue that current criteria for sepsis in adults and children fail to adequately consider one of the most common sepsis-related organ dysfunctions, acute kidney injury, which has important implications for diagnosis and patient outcomes.