Bisphosphonates are used for skeletal protection in osteoporosis, cancer bone metastasis, multiple myeloma, and Paget's disease of the bone; however, these drugs also have the potential for causing a number of adverse effects. While these do not limit bisphosphonate use, the incidence of these adverse events can be minimized if appropriate care is taken with their administration, and by maintaining appropriate surveillance and patient care, as discussed in this review.
- Colin R Dunstan
- Dieter Felsenberg
- Markus J Seibel