Nature Search

An unusual supernova in the error box of the γ-ray burst of 25 April 1998

T. J. Galama
P. M. Vreeswijk
P. Ianna
Research15 Oct 1998
Nature

Volume: 395, P: 670-672
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug

Drug-loaded nanoparticles allow controlled release and enhanced delivery, yet understanding in vivobehavior has been difficult. Here, the authors develop a platinum prodrug coupled to a polymer platform, and use intravital imaging to show that the nanoparticle accumulates in macrophages, from the which drug redistributes to neighboring tumour cells.

Miles A. Miller
Yao-Rong Zheng
Ralph Weissleder
ResearchOpen Access27 Oct 2015
Nature Communications

Volume: 6, P: 1-13
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.

Bukhtiar H Shah
Huma Rasheed
Sheikh A Saeed
ResearchOpen Access01 Dec 2001
Experimental & Molecular Medicine

Volume: 33, P: 226-233
Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

The beneficial effects of exercise on cardiovascular disease are linked to decreased inflammation through crosstalk between adipose tissue and hematopoietic progenitor cells in the bone marrow.

Vanessa Frodermann
David Rohde
Matthias Nahrendorf
Research07 Nov 2019
Nature Medicine

Volume: 25, P: 1761-1771
Spondylometaphyseal dysplasia in mice carrying a dominant negative mutation in a matrix protein specific for cartilage-to-bone transition

Olena Jacenko
Phyllis A. LuValle
Bjorn R. Olsen
Research02 Sept 1993
Nature

Volume: 365, P: 56-61
SARS-CoV-2 infection status in corneal preservation solution and COVID-19 prevalence after corneal transplantation

Yuki Wasai
Naoyuki Yamada
Kazuhiro Kimura
ResearchOpen Access14 Feb 2024
Scientific Reports

Volume: 14, P: 1-7
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease

In vivo imaging of inflammation is crucial for detection and monitoring of many pathologies and noninvasive macrophage quantification has been suggested as a possible approach. Here Keliher et al. describe novel polyglucose nanoparticle tracers that are rapidly excreted by the kidney and with high affinity for macrophages in atherosclerotic plaques.

Edmund J. Keliher
Yu-Xiang Ye
Matthias Nahrendorf
ResearchOpen Access16 Jan 2017
Nature Communications

Volume: 8, P: 1-12
Resolving cancer–stroma interfacial signalling and interventions with micropatterned tumour–stromal assays

Gene expression changes at the tumour–stroma interface are associated with epithelial cancer progression. Here, the authors describe a new in vitrosystem based on cell micropatterning and laser microdissection for examining the tumour–stromal interaction.

Keyue Shen
Samantha Luk
Biju Parekkadan
Research09 Dec 2014
Nature Communications

Volume: 5, P: 1-11
Effect of myofibril passive elastic properties on the mechanical communication between motor proteins on adjacent sarcomeres

Takumi Washio
Seine A. Shintani
Toshiaki Hisada
ResearchOpen Access27 Jun 2019
Scientific Reports

Volume: 9, P: 1-17
Publisher Correction: Pluripotent stem cell-derived model of the post-implantation human embryo

Bailey A. T. Weatherbee
Carlos W. Gantner
Magdalena Zernicka-Goetz
Amendments and CorrectionsOpen Access17 Aug 2023
Nature

Volume: 621, P: E30
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

Cold-induced activation of thermogenesis in white adipose tissue (WAT), or ‘beiging’, is associated with WAT angiogenesis. Here the authors show that PDGF-CC is secreted from endothelial cells in the context of WAT angiogenesis and its paracrine action on adipocytes contributes to cold-induced beiging.

Takahiro Seki
Kayoko Hosaka
Yihai Cao
ResearchOpen Access05 Aug 2016
Nature Communications

Volume: 7, P: 1-16
Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation

The protein OASIS belongs to the CREB/ATF transcription factor family and is involved in endoplasmic reticulum stress responses. Saito and colleagues show that these stress responses temporally activate OASIS in neural precursor cells, resulting in their differentiation into astrocytes.

Atsushi Saito
Soshi Kanemoto
Kazunori Imaizumi
ResearchOpen Access24 Jul 2012
Nature Communications

Volume: 3, P: 1-13
A novel risk classification score for malignant ureteral obstruction: a multicenter prospective validation study

Kouji Izumi
Takashi Shima
Atsushi Mizokami
ResearchOpen Access24 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Activation of Statl by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

Wu-Chou S. Su
Motoo Kitagawa
Xin-Yuan Fu
Research20 Mar 1997
Nature

Volume: 386, P: 288-292
Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton

Biosensors so far have mostly reported external traction forces exerted against the extracellular matrix or within adhesion receptors. Here, the authors present a sensor that reports molecular tension within the F-actin cytoskeleton.

Sorosh Amiri
Camelia Muresan
Michael Murrell
ResearchOpen Access04 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Magnetized fast isochoric laser heating for efficient creation of ultra-high-energy-density states

It is desirable to deposit more energy in the dense plasma core to trigger the fusion ignition. Here the authors demonstrate enhanced energy coupling from laser to plasma core by using solid targets and guiding the transport of relativistic electron beam with external magnetic field.

Shohei Sakata
Seungho Lee
Shinsuke Fujioka
ResearchOpen Access26 Sept 2018
Nature Communications

Volume: 9, P: 1-9
Collocated observations of cloud condensation nuclei, particle size distributions, and chemical composition

Julia Schmale
Silvia Henning
Martin Gysel
ResearchOpen Access14 Mar 2017
Scientific Data

Volume: 4, P: 1-27
Interleukin 6: from bench to bedside

Disruption of the regulation of the cytokine interleukin 6 can induce inflammatory diseases, many of which have proven refractory to conventional therapies. The clinical use of a humanized monoclonal antibody to block signaling from the interleukin 6 receptor is discussed in this Review.

Norihiro Nishimoto
Tadamitsu Kishimoto
Reviews01 Nov 2006
Nature Clinical Practice Rheumatology

Volume: 2, P: 619-626
A pathway regulated by cell cycle inhibitor p27^Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance

Lequn Li
Yoshiko Iwamoto
Vassiliki A Boussiotis
Research01 Oct 2006
Nature Immunology

Volume: 7, P: 1157-1165
Grb2 binding to the different isoforms of Ret tyrosine kinase

L Alberti
M G Borrello
M A Pierotti
Research04 Sept 1998
Oncogene

Volume: 17, P: 1079-1087
High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation

A Bounacer
R Wicker
H G Suárez
Research11 Sept 1997
Oncogene

Volume: 15, P: 1263-1273
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy

Methods for quantitative, automated in vivo cell-cycle profiling are applied to tumor xenografts in the mouse to study the effects of drug treatment.

Deepak R Chittajallu
Stefan Florian
Timothy J Mitchison
Research13 Apr 2015
Nature Methods

Volume: 12, P: 577-585
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

Tumour-associated macrophages (TAM) can be used as prognostic indicators in cancer. Here, the authors establish a platform for high-throughput 3D microscopy in murine lung carcinoma that allows to visualize TAMs infiltration throughout the entire lung, response to CSF-1R blockade and nanoparticle drug delivery.

Michael F. Cuccarese
J. Matthew Dubach
Ralph Weissleder
ResearchOpen Access08 Feb 2017
Nature Communications

Volume: 8, P: 1-10
Novel ecto-tagged integrins reveal their trafficking in live cells

Integrins are cell-surface adhesion receptors that are modulated by endo-exocytic trafficking, but existing tools to study this process can interfere with function. Here the authors develop β1 integrins carrying traceable tags in the extracellular domain; a pH-sensitive pHlourin tag or a HaloTag to facilitate dye attachment.

Clotilde Huet-Calderwood
Felix Rivera-Molina
David A. Calderwood
ResearchOpen Access18 Sept 2017
Nature Communications

Volume: 8, P: 1-13
Mindfulness Meditation Activates Altruism

Sage K. Iwamoto
Marcus Alexander
Akihiro Nishi
ResearchOpen Access16 Apr 2020
Scientific Reports

Volume: 10, P: 1-7
Fully automated rapid quantification of Hepatitis C Virus RNA in human plasma and serum by integrated on-chip RT-qPCR and capillary electrophoresis

Samuel D. H. Chan
Hidenori Toyoda
Jian-Ping Zhang
ResearchOpen Access30 Apr 2020
Scientific Reports

Volume: 10, P: 1-8
IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A

Urra et al. discover that IRE1α, an ER stress mediator, interacts with filamin A and controls actin dynamics and cell migration in mouse, Drosophila and zebrafish models in a manner independent of its canonical function.

Hery Urra
Daniel R. Henriquez
Claudio Hetz
Research16 Jul 2018
Nature Cell Biology

Volume: 20, P: 942-953
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Effect of bisphosphonates on pain and quality of life in patients with bone metastases

Bone is the most common organ for tumor metastasis, especially in patients with cancers of the breast or prostate. Bone metastases disrupt skeletal metabolism, resulting in considerable skeletal morbidity and chronic pain. This Review summarizes the clinical trial data of bisphosphonates for the prevention of skeletal-related events and the palliation of bone pain. The authors discuss how nitrogen-containing bisphosphonates have demonstrated great promise in patients with advanced malignancies.

Luis Costa
Pierre P Major
Reviews03 Feb 2009
Nature Reviews Clinical Oncology

Volume: 6, P: 163-174
Nuclear Accumulation of β-Catenin Occurs Commonly in the Epithelial Cells of Juvenile Polyps

Michiko Iwamoto
Edward J Hoffenberg
Dennis J Ahnen
Research01 Jan 2005
Pediatric Research

Volume: 57, P: 4-9
Publisher Correction: ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma

Víctor A. Arrieta
Andrew X. Chen
Adam M. Sonabend
Amendments and Corrections11 Feb 2022
Nature Cancer

Volume: 3, P: 373
Constraint on the matter–antimatter symmetry-violating phase in neutrino oscillations

The T2K experiment constrains CP symmetry in neutrino oscillations, excluding 46% of possible values of the CP violating parameter at a significance of three standard deviations; this is an important milestone to test CP symmetry conservation in leptons and whether the Universe’s matter–antimatter imbalance originates from leptons.

K. Abe
R. Akutsu
A. Zykova
Research15 Apr 2020
Nature

Volume: 580, P: 339-344
Anthracycline-induced inhibition of membrane permeability functions dependent on metabolic energy

A C Croce
E Prosperi
G Bottiroli
Research01 Dec 1986
British Journal of Cancer

Volume: 54, P: 943-950
Heritability and Y-chromosome influence in the jack male life history of chinook salmon (Oncorhynchus tshawytscha)

D D Heath
L Rankin
J M Shrimpton
Research19 Sept 2002
Heredity

Volume: 89, P: 311-317
Differential Effects of Growth Hormone and Alfa Calcidol on Trabecular and Cortical Bones in Hypophysectomized Rats

Afshan A Chaudhry
Mariano Castro-Magana
James K Yeh
Research01 Apr 2009
Pediatric Research

Volume: 65, P: 403-408
266 GLUCONEOGENESIS BY THE FETAL SHEEP KIDNEY

Christine A Gleason
Harriet S Iwamoto
Abraham M Rudolph
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 155
Harnessing an integrated glyco-nanovaccine technology for enhanced cancer immunotherapy

Niimura et al. investigates the potential of an integrated glyco-nanovaccine (iGN) comprising gold nanoparticles conjugated with a synthetic Toll-like receptor 7 ligand, sugar chains, and peptide antigens for cancer immunotherapy. Treatment with iGN increases tumor-infiltrating CD8+ T cells and inhibits tumor growth.

Mayumi Niimura
Yasuhisa Sakamoto
Toshiro Moroishi
ResearchOpen Access29 Aug 2025
Communications Medicine

Volume: 5, P: 1-15
Publisher Correction: Integrated exome and RNA sequencing of dedifferentiated liposarcoma

Makoto Hirata
Naofumi Asano
Koichi Matsuda
Amendments and CorrectionsOpen Access19 Feb 2020
Nature Communications

Volume: 11, P: 1
Tissue-dependent mechanosensing by cells derived from human tumors

Kshitiz Parihar
Jonathan Nukpezah
Ravi Radhakrishnan
ResearchOpen Access06 Aug 2025
npj Biological Physics and Mechanics

Volume: 2, P: 1-14
Effect of individual spinal muscle activities on upright posture using a human body finite element model

Yuko Nakahira
Masami Iwamoto
Ken Ishii
ResearchOpen Access27 Jan 2025
Scientific Reports

Volume: 15, P: 1-14
Proteomic and metabolic prediction of response to therapy in gastrointestinal cancers

The development of multimodality and targeted treatment strategies has improved the prognosis of patients with gastrointestinal cancers. Not all patients, however, benefit equally from these treatment approaches, and the ability to predict who will respond positively to a treatment type is of particular importance. This Review discusses the role of biomarkers and metabolic imaging approaches in the prediction of response to therapy early on in treatment.

Ken Herrmann
Axel Walch
Matthias PA Ebert
Reviews01 Mar 2009
Nature Reviews Gastroenterology & Hepatology

Volume: 6, P: 170-183
The translational potential of microRNAs as biofluid markers of urological tumours

MicroRNA secretion pathways are dysregulated in cancer, making them attractive candidate molecules for liquid biopsies and studies have shown that they are noninvasive diagnostic, prognostic and surveillance markers in urological carcinomas. However, methodological and analytical pitfalls exist and require addressing to enable future translation of microRNA analysis into clinical practice.

Annika Fendler
Carsten Stephan
Klaus Jung
Reviews02 Nov 2016
Nature Reviews Urology

Volume: 13, P: 734-752
270 IS EGF A MEDIATOR OF GLUCOCORTICOID ACTION ON DEVELOPING FETAL LUNG?

Ian Gross
Diane W Dynia
Joseph B Warshaw
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 155
Core-binding factor β interacts with Runx2 and is required for skeletal development

Carolina A. Yoshida
Tatsuya Furuichi
Toshihisa Komori
Research18 Nov 2002
Nature Genetics

Volume: 32, P: 633-638
Function of the C-Terminal Propeptide of Surfactant Protein B (SP-B). • 224

Henry T. Akinbi
Joanette S. Breslin
Timothy E. Weaver
Research01 Apr 1997
Pediatric Research

Volume: 41, P: 40
Characterization of alginate extracted from Sargassum latifolium and its use in Chlorella vulgaris growth promotion and riboflavin drug delivery

Shimaa R. Dalal
Mervat H. Hussein
Sami A. Shaaban-Dessuuki
ResearchOpen Access18 Aug 2021
Scientific Reports

Volume: 11, P: 1-17
Effects of Perfluorocarbon in Spontaneously Breathing Mice • 1660

Beth E Haberman
Susan E Wert
Harriet S Iwamoto
Research01 Apr 1998
Pediatric Research

Volume: 43, P: 283
IL-12-STAT4-IFN-γ axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

You-Sun Kim
Seng-Jin Choi
Yoon-Keun Kim
ResearchOpen Access01 Jul 2010
Experimental & Molecular Medicine

Volume: 42, P: 533-546
Acute Hyperoxic Injury Attenuates the Relaxing Effects of “Loop” Diuretics and Salbutamol on Large Airways of Newborn Guinea Pigs

G Andre Marinkovich
Bruce E Pichoff
Kenneth T Nakamura
Research01 Sept 1995
Pediatric Research

Volume: 38, P: 280-285
Prostate cancer incidence varies among males from different Y-chromosome lineages

A A Ewis
J Lee
Y Nakahori
Research09 May 2006
Prostate Cancer and Prostatic Diseases

Volume: 9, P: 303-309

Search

Filter By:

Search

Quick links