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Showing 1–50 of 56 results

Advanced filters: Author: A L Edel Clear advanced filters

Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer

G Attard
J Clark
C S Cooper
Research16 Jul 2007
Oncogene

Volume: 27, P: 253-263
A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison

The authors report a meta-analysis of methylome-wide association studies, identifying 15 significant CpG sites linked to major depression, revealing associations with inflammatory markers and suggesting potential causal relationships through Mendelian randomization analysis.

Xueyi Shen
Miruna Barbu
Andrew M. McIntosh
ResearchOpen Access16 Sept 2025
Nature Mental Health

Volume: 3, P: 1152-1167
Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation

Dimitre R. Simeonov
Benjamin G. Gowen
Alexander Marson
Amendments and Corrections13 Jun 2018
Nature

Volume: 559, P: E13
Discovery of stimulation-responsive immune enhancers with CRISPR activation

The authors use tiled CRISPR activation for functional enhancer discovery across two autoimmunity risk loci, CD69 and IL2RA, and identify elements with features of stimulus-responsive enhancers, including an IL2RA enhancer that harbours a fine-mapped autoimmunity risk variant.

Dimitre R. Simeonov
Benjamin G. Gowen
Alexander Marson
Research30 Aug 2017
Nature

Volume: 549, P: 111-115
Oscillations in the Surface Resistance of Bismuth as a Function of Magnetic Field

N. W. A. MARSH
J. E. AUBREY
Research27 Feb 1965
Nature

Volume: 205, P: 894
A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues

Steele et al. use single-cell RNA sequencing and spatial transcriptomics to provide an atlas of adult human skin fibroblasts in healthy and diseased human skin.

Lloyd Steele
Bayanne Olabi
Muzlifah Haniffa
ResearchOpen Access24 Sept 2025
Nature Immunology

Volume: 26, P: 1807-1820
Thymic regulatory T cells arise via two distinct developmental programs

Farrar and colleagues show that thymic T_reg cells are generated through two distinct developmental programs that are both required for a comprehensive T_reg cell repertoire.

David L. Owen
Shawn A. Mahmud
Michael A. Farrar
Research14 Jan 2019
Nature Immunology

Volume: 20, P: 195-205
Transmission of Laser Beams through Various Transparent Rods for Biomedical Applications

JOHN A. GOLDMAN
ROBERT MEYER
Research27 Feb 1965
Nature

Volume: 205, P: 892-894
Oligo-Miocene rift of Sardinia and the early history of the Western Mediterranean Basin

A. Cherchi
L. Montadert
Research19 Aug 1982
Nature

Volume: 298, P: 736-739
Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

Hans Frauenfelder
Gregory A. Petsko
Demetrius Tsernoglou
Research01 Aug 1979
Nature

Volume: 280, P: 558-563
Reflectance of Coal Vitrains in the Visible and Ultra-Violet compared with that of Graphite

L. A. GILBERT
Research09 Apr 1960
Nature

Volume: 186, P: 143-144
The continuity of thick filaments between sarcomeres in honey bee flight muscle

K. Trombitas
A. Tigyi-Sebes
Research27 Sept 1979
Nature

Volume: 281, P: 319-320
Rare disease gene association discovery in the 100,000 Genomes Project

A rare variant burden analytical framework for Mendelian diseases was developed and applied to data from the 100,000 Genomes Project, identifying 69 probable new disease–gene associations.

Valentina Cipriani
Letizia Vestito
Damian Smedley
ResearchOpen Access26 Feb 2025
Nature

P: 1-9
1α, 25-Dihydroxyvitamin D₃, and 24,25-dihydroxyvitamin D₃ in vitro synthesis by human decidua and placenta

Y. Weisman
A. Harell
A. Golander
Research27 Sept 1979
Nature

Volume: 281, P: 317-319
Potassium Fluxes in Quiescent and Beating Frog Ventricle

J. F. LAMB
J. A. S. MCGUIGAN
Research13 Mar 1965
Nature

Volume: 205, P: 1115-1116
Dimeric β-cyclodextrin complexes may mimic membrane diffusion transport

JOHN J. STEZOWSKI
KURT H. JOGUN
KLAUS BARTELS
Research10 Aug 1978
Nature

Volume: 274, P: 617-619
A prenatal skin atlas reveals immune regulation of human skin morphogenesis

A comprehensive multi-omics reference atlas of prenatal human skin shows that innate immune cells crosstalk with non-immune cells to perform pivotal roles in skin morphogenesis, including the formation of hair follicles.

Nusayhah Hudaa Gopee
Elena Winheim
Muzlifah Haniffa
ResearchOpen Access16 Oct 2024
Nature

Volume: 635, P: 679-689
QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction

Defects in growth hormone (GH) action account for a substantial percentage of endocrine causes of growth failure. Here, the authors report that QSOX2 deficiency modulates human growth by impairing GH-STAT5B downstream activities and mitochondrial dynamics, contributing to multi-system dysfunction.

Avinaash V. Maharaj
Miho Ishida
Helen L. Storr
ResearchOpen Access28 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Analogues in other mammals and in fish of human plasma proteins, C-reactive protein and amyloid P component

M. B. PEPYS
A. C. DASH
A. FEINSTEIN
Research11 May 1978
Nature

Volume: 273, P: 168-170
Kinetics of smooth and skeletal muscle activation by laser pulse photolysis of caged inositol 1,4,5-trisphosphate

J. W. Walker
A. V. Somlyo
D. R. Trentham
Research21 May 1987
Nature

Volume: 327, P: 249-252
The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer

L Shan
L Ambroisine
Y-J Lu
Research23 Feb 2010
Prostate Cancer and Prostatic Diseases

Volume: 13, P: 117-125
Author Correction: Electrotunable nanoplasmonic liquid mirror

Yunuen Montelongo
Debabrata Sikdar
Alexei A. Kornyshev
Amendments and Corrections10 May 2019
Nature Materials

Volume: 18, P: 650
Self-assembled nanoparticle arrays for multiphase trace analyte detection

Nanoplasmonic structures that can detect trace analytes via surface-enhanced Raman spectroscopy typically require sophisticated nanofabrication techniques. Self-assembly of gold nanoparticles into close-packed arrays at liquid/liquid and liquid/air interfaces is now used for the detection of multi-analytes from aqueous, organic or air phases.

Michael P. Cecchini
Vladimir A. Turek
Joshua B. Edel
Research18 Nov 2012
Nature Materials

Volume: 12, P: 165-171
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D

AMBRA1 is the main regulator of the degradation of D-type cyclins, and loss of AMBRA1 promotes cell proliferation and tumour growth, and reduces the sensitivity of cancer cells to inhibition of CDK4 and CDK6.

Andrea C. Chaikovsky
Chuan Li
Julien Sage
Research14 Apr 2021
Nature

Volume: 592, P: 794-798
Electrotunable nanoplasmonic liquid mirror

Designing fully tunable metamaterials for applications ranging from sensors to superlenses remains a challenge. A reversible electrotuneable liquid mirror based on voltage-controlled self-assembly/disassembly plasmonic nanoparticles is now reported.

Yunuen Montelongo
Debabrata Sikdar
Alexei A. Kornyshev
Research11 Sept 2017
Nature Materials

Volume: 16, P: 1127-1135
Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy

Direct observation of G-quadruplexes (G4s) in live cells is challenging. Here the authors report a method to identify G4s within the nuclei of live and fixed cells using a fluorescent probe combined with fluorescence lifetime imaging microscopy.

Peter A. Summers
Benjamin W. Lewis
Ramon Vilar
ResearchOpen Access08 Jan 2021
Nature Communications

Volume: 12, P: 1-11
Effects of Reserpine Treatment on Dietary Adaptation of the Rat Exocrine Pancreas

Dee A Hazlett
Patsy M Brannon
Research01 Feb 1988
Pediatric Research

Volume: 23, P: 176-180
Charge mosaics on contact-electrified dielectrics result from polarity-inverting discharges

Under certain conditions, contact electrification can lead to heterogeneous surface charge distributions—charge mosaics. Experiments and theory now show that these arise from electrostatic discharges between disjoining surfaces.

Yaroslav I. Sobolev
Witold Adamkiewicz
Bartosz A. Grzybowski
Research08 Sept 2022
Nature Physics

Volume: 18, P: 1347-1355
Sustained increases in atmospheric oxygen and marine productivity in the Neoproterozoic and Palaeozoic eras

Oxygen in shallow shelf waters rose linearly with atmospheric oxygen in the Neoproterozoic era, potentially driving the first radiation of marine animals, but widespread ocean oxygenation came later, according to reconstructions of oxygen levels and marine productivity.

Richard G. Stockey
Devon B. Cole
Erik A. Sperling
ResearchOpen Access02 Jul 2024
Nature Geoscience

Volume: 17, P: 667-674
Towards Electrotuneable Nanoplasmonic Fabry–Perot Interferometer

Hayley Weir
Joshua B. Edel
Debabrata Sikdar
ResearchOpen Access12 Jan 2018
Scientific Reports

Volume: 8, P: 1-7
Caspase signalling controls microglia activation and neurotoxicity

Miguel A. Burguillos
Tomas Deierborg
Bertrand Joseph
Research09 Mar 2011
Nature

Volume: 472, P: 319-324
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype

Gliomas recruit and manipulate microglial function to promote their growth. Joseph and colleagues reveal the molecular basis of this manipulation by showing that gliomas trigger S-nitrosylation of microglial caspase-3 and thereby initiate a tumor-promoting phenotype.

Xianli Shen
Miguel A Burguillos
Bertrand Joseph
Research12 Sept 2016
Nature Immunology

Volume: 17, P: 1282-1290
PKCα integrates spatiotemporally distinct Ca²⁺ and autocrine BDNF signaling to facilitate synaptic plasticity

Through the development of novel PKC biosensors, the authors describe how PKCα, but not other classical isozymes, facilitates plasticity in dendritic regions through the integration of recent synaptic plasticity with current, local synaptic input.

Lesley A Colgan
Mo Hu
Ryohei Yasuda
Research16 Jul 2018
Nature Neuroscience

Volume: 21, P: 1027-1037
Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

Hydroxychloroquine and chloroquine have been investigated as a potential treatment for Covid-19 in several clinical trials. Here the authors report a meta-analysis of published and unpublished trials, and show that treatment with hydroxychloroquine for patients with Covid-19 was associated with increased mortality, and there was no benefit from chloroquine.

Cathrine Axfors
Andreas M. Schmitt
Lars G. Hemkens
ResearchOpen Access15 Apr 2021
Nature Communications

Volume: 12, P: 1-13
Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network

Anthony M. Boutelle
Aicha R. Mabene
Laura D. Attardi
Research22 Apr 2025
Cell Death & Differentiation

P: 1-16
MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling

Shan Xin
Constanze Mueller
Joel A. Schick
ResearchOpen Access18 Oct 2021
Cell Death & Differentiation

Volume: 29, P: 670-686
A genome-wide scan shows evidence for local adaptation in a widespread keystone Neotropical forest tree

Rosane G. Collevatti
Evandro Novaes
Dario Grattapaglia
ResearchOpen Access12 Feb 2019
Heredity

Volume: 123, P: 117-137
Delayed (“Secondary”) Cerebral Energy Failure after Acute Hypoxia-Ischemia in the Newborn Piglet: Continuous 48-Hour Studies by Phosphorus Magnetic Resonance Spectroscopy

Ann Lorek
Y Takei
E O R Reynolds
Research01 Dec 1994
Pediatric Research

Volume: 36, P: 699-706
Whales Use Distinct Strategies to Counteract Solar Ultraviolet Radiation

Laura M. Martinez-Levasseur
Mark A. Birch-Machin
Karina Acevedo-Whitehouse
ResearchOpen Access30 Aug 2013
Scientific Reports

Volume: 3, P: 1-6
Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer

G G Van den Eynden
I Van der Auwera
E A Van Marck
ResearchOpen Access25 Oct 2005
British Journal of Cancer

Volume: 93, P: 1128-1136
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Chemotherapy for mobilisation of Ph-negative progenitor cells from patients with CML: impact of different mobilisation regimens

M Deininger
W Pönisch
D Niederwieser
Research06 Jul 2001
Bone Marrow Transplantation

Volume: 27, P: 1125-1132
Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis

Anneke I den Hollander
Robert K Koenekoop
Ronald Roepman
Research03 Jun 2007
Nature Genetics

Volume: 39, P: 889-895
Oncogenic driver mutations predict outcome in a cohort of head and neck squamous cell carcinoma (HNSCC) patients within a clinical trial

Javier Fernández-Mateos
Jéssica Pérez-García
Juan Jesús Cruz-Hernández
ResearchOpen Access06 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
Bioavailability of α-linolenic acid from flaxseed diets as a function of the age of the subject

A Patenaude
D Rodriguez-Leyva
G N Pierce
Research08 Jul 2009
European Journal of Clinical Nutrition

Volume: 63, P: 1123-1129
PTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients

Elizabeth A Punnoose
Roberta Ferraldeschi
Johann de Bono
ResearchOpen Access17 Sept 2015
British Journal of Cancer

Volume: 113, P: 1225-1233
Serotonin Receptors in Suicide Victims with Major Depression

Craig A Stockmeier
Ginny E Dilley
Herbert Y Meltzer
Research01 Feb 1997
Neuropsychopharmacology

Volume: 16, P: 162-173
Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study

Rajiv V. Dave
Baek Kim
Zaid Al-Ishaq
ResearchOpen Access25 Mar 2021
British Journal of Cancer

Volume: 124, P: 1785-1794
The ETV6-NTRK3 gene fusion encodes a chimeric protein tyrosine kinase that transforms NIH3T3 cells

Daniel H Wai
Stevan R Knezevich
Poul HB Sorensen
Research01 Mar 2000
Oncogene

Volume: 19, P: 906-915
Theory of tailorable optical response of two-dimensional arrays of plasmonic nanoparticles at dielectric interfaces

Debabrata Sikdar
Alexei A. Kornyshev
ResearchOpen Access22 Sept 2016
Scientific Reports

Volume: 6, P: 1-16

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