Nature Search

Autonomous chaotic behaviour of the slime mould Dictyostelium discoideum predicted by a model for cyclic AMP signalling

J. L. Martiel
A. Goldbeter
Research01 Feb 1985
Nature

Volume: 313, P: 590-592
Shifting sands

Martin A. Conway
Books & Arts21 Mar 1996
Nature

Volume: 380, P: 214
Symmetry Breaking Instabilities in Biological Systems

I. PRIGOGINE
R. LEFEVER
M. HERSCHKOWITZ-KAUFMAN
Research30 Aug 1969
Nature

Volume: 223, P: 913-916
Network dynamics and cell physiology

John J. Tyson
Kathy Chen
Bela Novak
Comments & Opinion01 Dec 2001
Nature Reviews Molecular Cell Biology

Volume: 2, P: 908-916
The genetic landscape of a metabolic interaction

Reynolds and colleagues examine a biochemically-mediated epistatic interaction between metabolic enzymes involved in folate metabolism and show that biochemical coupling shapes the range of enzyme activities sufficient to rescue cell growth.

Thuy N. Nguyen
Christine Ingle
Kimberly A. Reynolds
ResearchOpen Access18 Apr 2024
Nature Communications

Volume: 15, P: 1-18
Chemical and isotopic evidence of thermochemical sulphate reduction by light hydrocarbon gases in deep carbonate reservoirs

H. Roy Krouse
Christian A. Viau
Stan Halas
Research02 Jun 1988
Nature

Volume: 333, P: 415-419
Complex dynamics in a synchronized cell-free genetic clock

In theory, driven biological oscillators can display complex dynamic behaviors, but these are experimentally difficult to observe. Here the authors, using microfluidics, show that a synthetic cell-free gene oscillator displays period doubling and even quadrupling.

Lukas Aufinger
Johann Brenner
Friedrich C. Simmel
ResearchOpen Access23 May 2022
Nature Communications

Volume: 13, P: 1-9
Possible Indirect Method for the Detection of γ-Ray Flashes from Supernovae

N. A. PORTER
Research19 Oct 1973
Nature

Volume: 245, P: 366-367
Separation of Effects of Auxin and Ethylene in Pea Roots

PETER C. SCOTT
LOGAN A. NORRIS
Research26 Sept 1970
Nature

Volume: 227, P: 1366-1367
Conflict between Positive and Negative Feedback as an Explanation for the Initiation of Aggregation in Slime Mould Amoebae

EVELYN F. KELLER
LEE A. SEGEL
Research26 Sept 1970
Nature

Volume: 227, P: 1365-1366
Back to the future: education for systems-level biologists

Systems biology has produced a challenge to the educational system. In the future, practitioners of biology at the systems level will need combinations of skills that are rarely found in individual scientists today. So, how should we educate students to succeed across scientific disciplines?

Ned Wingreen
David Botstein
Comments & Opinion20 Sept 2006
Nature Reviews Molecular Cell Biology

Volume: 7, P: 829-832
Proteins, drug targets and the mechanisms they control: the simple truth about complex networks

To fully realize the potential of molecularly targeted therapies for cancer and other human diseases, a new level of knowledge about the complex cellular control circuitry is required. Here, the authors explore mathematical paradigms that facilitate the design of network-targeted anticancer drugs.

Robyn P. Araujo
Lance A. Liotta
Emanuel F. Petricoin
Reviews01 Nov 2007
Nature Reviews Drug Discovery

Volume: 6, P: 871-880
Design principles of biochemical oscillators

Biochemical oscillations are generated by complex interactions between genes, proteins and cellular metabolites and underlie many processes. Oscillatory behaviour is characterized by negative feedback with time delay, nonlinearity of the reaction kinetics and proper balancing of the timescales of opposing chemical reactions.

Béla Novák
John J. Tyson
Reviews30 Oct 2008
Nature Reviews Molecular Cell Biology

Volume: 9, P: 981-991
Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

G. GERISCH
H. FROMM
U. WICK
Research12 Jun 1975
Nature

Volume: 255, P: 547-549
Control of ribosome synthesis

A. A. Travers
News & Views12 Jun 1975
Nature

Volume: 255, P: 523
Artists' offspring

L. V. Rubinstein
A. D. Koutsoukos
Correspondence14 May 1992
Nature

Volume: 357, P: 106
No Gulf at Cambridge

A. S. V. BURGEN
H. B. F. DIXON
F. G. YOUNG
Correspondence27 Sept 1969
Nature

Volume: 223, P: 1395
Understanding systems-level properties: timely stories from the study of clocks

Circadian clocks are archetypal complex biological systems and so clock research has been at the forefront of developing and exploiting systems biology research approaches. This work has uncovered systems-level properties, such as robustness and periodicity, and provides lessons for other research fields.

John B. Hogenesch
Hiroki R. Ueda
Reviews10 May 2011
Nature Reviews Genetics

Volume: 12, P: 407-416
A symbolic network-based nonlinear theory for dynamical systems observability

Christophe Letellier
Irene Sendiña-Nadal
Murilo S. Baptista
ResearchOpen Access28 Feb 2018
Scientific Reports

Volume: 8, P: 1-15
Cell cycle regulators and hematopoiesis

Richard A Steinman
Reviews21 May 2002
Oncogene

Volume: 21, P: 3403-3413

Search

Autonomous chaotic behaviour of the slime mould Dictyostelium discoideum predicted by a model for cyclic AMP signalling

Shifting sands

Symmetry Breaking Instabilities in Biological Systems

Network dynamics and cell physiology

The genetic landscape of a metabolic interaction

Chemical and isotopic evidence of thermochemical sulphate reduction by light hydrocarbon gases in deep carbonate reservoirs

Complex dynamics in a synchronized cell-free genetic clock

Possible Indirect Method for the Detection of γ-Ray Flashes from Supernovae

Separation of Effects of Auxin and Ethylene in Pea Roots

Conflict between Positive and Negative Feedback as an Explanation for the Initiation of Aggregation in Slime Mould Amoebae

Back to the future: education for systems-level biologists

Proteins, drug targets and the mechanisms they control: the simple truth about complex networks

Design principles of biochemical oscillators

Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

Control of ribosome synthesis

Artists' offspring

No Gulf at Cambridge

Understanding systems-level properties: timely stories from the study of clocks

A symbolic network-based nonlinear theory for dynamical systems observability

Cell cycle regulators and hematopoiesis

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