Nature Search

Retinal Summation and Human Visual Thresholds

R. A. WEALE
Research18 Jan 1958
Nature

Volume: 181, P: 154-156
Design of a novel shunt active harmonic compensator with AUV-PQ-SRF reference current extraction, OSV-MPC and SMC techniques

Kumar Reddy Cheepati
E. Parimalasundar
Aravind Pitchai
ResearchOpen Access06 Aug 2025
Scientific Reports

Volume: 15, P: 1-21
Towards carbon-neutral and clean propulsion in heavy-duty transportation with hydroformylated Fischer–Tropsch fuels

For synthetic fuels to aid in a transition towards cleaner transportation, they must fulfil criteria related to scalability, compatibility with existing infrastructure and environmental impacts. Here the authors show that hydroformylated Fischer–Tropsch fuels comprising optimized alkane–alcohol blends are promising candidates when judged by these metrics.

Simon Voelker
Niklas Groll
André Bardow
ResearchOpen Access08 Jul 2024
Nature Energy

Volume: 9, P: 1220-1229
Surgical stabilisation of the cervical spine: a comparative analysis of anterior and posterior spine fusions

Daniel A Capen
Russell W Nelson
Douglas E Garland
Research01 Apr 1987
Spinal Cord

Volume: 25, P: 111-119
Altered cell differentiation and proliferation in mice lacking p57^KIP2 indicates a role in Beckwith–Wiedemann syndrome

Pumin Zhang
Nanette J. Liégeois
Stephen J. Elledge
Research08 May 1997
Nature

Volume: 387, P: 151-158
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD

Lysosomes maintain RPE health via TFEB/E3-regulated autophagy. Here, the authors show deregulated AKT2/SIRT5/TFEB signaling in the RPE inhibits both lysosomal and mitochondrial function and leads to AMD, suggesting this pathway might provide a therapeutic target for AMD.

Sayan Ghosh
Ruchi Sharma
Debasish Sinha
ResearchOpen Access21 Jul 2024
Nature Communications

Volume: 15, P: 1-18
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens

Sharon D. Morgenbesser
Bart O. Williams
Ronald A. DePinho
Research01 Sept 1994
Nature

Volume: 371, P: 72-74
The active evolutionary lives of echinoderm larvae

R A Raff
M Byrne
Reviews19 Jul 2006
Heredity

Volume: 97, P: 244-252
BRAF^V600E melanoma cells secrete factors that activate stromal fibroblasts and enhance tumourigenicity

C A Whipple
C E Brinckerhoff
ResearchOpen Access12 Aug 2014
British Journal of Cancer

Volume: 111, P: 1625-1633
Spatio-temporal patterns of genetic variation in Arbacia lixula, a thermophilous sea urchin in expansion in the Mediterranean

Rocío Pérez-Portela
Owen S. Wangensteen
Xavier Turon
Research14 Jun 2018
Heredity

Volume: 122, P: 244-259
Energy spread minimization in a beam-driven plasma wakefield accelerator

In a beam-driven plasma wakefield accelerator, the energy spread of an electron bunch is reduced with respect to the plasma entrance, which is achieved through setting a positive energy chirp that rotates the bunches’ longitudinal phase space.

R. Pompili
D. Alesini
A. Zigler
Research04 Jan 2021
Nature Physics

Volume: 17, P: 499-503
Lens α-crystallin: Function and structure

Joseph Horwitz
Michael P Bova
Phoebe L Stewart
Research01 May 1999
Eye

Volume: 13, P: 403-408
Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy

Retinal pigment epithelium (RPE) plays an important role in diabetic retinopathy (DR) progression. Here, the authors show AKT1 and AKT2 are reciprocally regulated in the RPE of DR donor tissue and diabetic mice, reducing Akt2 in RPE causing a compensatory increase in Akt1 and attenuating DR.

Haitao Liu
Nadezda A. Stepicheva
Debasish Sinha
ResearchOpen Access13 Oct 2022
Nature Communications

Volume: 13, P: 1-19
Free-electron lasing with compact beam-driven plasma wakefield accelerator

Using a compact, particle-beam-driven plasma-based accelerator to accelerate high-quality electron beams that are completely characterized in the six-dimensional phase space, free-electron lasing is observed with narrow-band amplified radiation in the infrared range.

R. Pompili
D. Alesini
M. Ferrario
Research25 May 2022
Nature

Volume: 605, P: 659-662
Publisher Correction: Coal-fired power plant closures and retrofits reduce asthma morbidity in the local population

Joan A. Casey
Jason G. Su
Meredith A. Barrett
Amendments and Corrections14 May 2020
Nature Energy

Volume: 5, P: 418
Improved asthma outcomes observed in the vicinity of coal power plant retirement, retrofit and conversion to natural gas

Transition from coal to gas, retrofitting and retirement of coal power plants are expected to reduce air pollution and therefore have positive health effects. Casey et al. present direct evidence of this phenomenon by reporting improved asthma outcomes in the wake of coal plant closure and retrofit in Louisville, Kentucky.

Joan A. Casey
Jason G. Su
Meredith A. Barrett
Research13 Apr 2020
Nature Energy

Volume: 5, P: 398-408
Influences of the comonomer type on the crystallization kinetics of high-density polyethylene

Crystallization kinetics of high-density polyethylene copolymers containing 1-butene and 1-hexene were investigated using differential scanning calorimetry (DSC), in-situ wide-angle X-ray diffraction (WAXD), and in-situ small-angle light scattering (SALS). Compared to 1-hexene copolymers, 1-butene copolymers exhibit slower isothermal crystallization, reduced spherulite growth, and higher lamellar surface free energy (σ_f), highlighting the pronounced impact of comonomer type on nucleation thermodynamics and lamellar development.

Wonchalerm Rungswang
Chatchai Jarumaneeroj
Supagorn Rugmai
Research14 Apr 2025
Polymer Journal

Volume: 57, P: 711-722
Femtosecond dynamics of energetic electrons in high intensity laser-matter interactions

R. Pompili
M. P. Anania
A. Zigler
ResearchOpen Access07 Oct 2016
Scientific Reports

Volume: 6, P: 1-7
Coal-fired power plant closures and retrofits reduce asthma morbidity in the local population

Retiring, transitioning or installing more stringent emissions controls in coal-fired power plants has the potential to decrease asthma attacks and asthma-related emergency department visits and hospitalizations in nearby communities. These health co-benefits should be considered in policy and decision making about coal-fired power plant retirement or retrofit.

Joan A. Casey
Jason G. Su
Meredith A. Barrett
News & Views01 May 2020
Nature Energy

Volume: 5, P: 365-366
The lens in diabetes

A J Bron
J Sparrow
R Blakytny
Research01 Mar 1993
Eye

Volume: 7, P: 260-275
Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart

M A C Fauchon
T J Pell
L V Mayne
ResearchOpen Access01 Aug 2005
Experimental & Molecular Medicine

Volume: 37, P: 311-322
Estimating the palliative effect of percutaneous endoscopic gastrostomy in an observational registry using principal stratification and generalized propensity scores

Pallavi S. Mishra-Kalyani
Brent A. Johnson
Qi Long
ResearchOpen Access19 Sept 2016
Scientific Reports

Volume: 6, P: 1-9
Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice

Qin Chen
John D Ash
Paul A Overbeek
Research18 Feb 2002
Oncogene

Volume: 21, P: 1028-1037
Recovery of hydrogen plasma at the sub-nanosecond timescale in a plasma-wakefield accelerator

The authors report about a proof-of-principle experiment that demonstrates the recovery of a Hydrogen plasma accelerator at the sub-nanosecond timescale. The result is obtained with a pump-andprobe setup and represent a step forward for the next-generation of compact high-repetition rate plasma-based accelerators.

R. Pompili
M. P. Anania
A. Zigler
ResearchOpen Access16 Jul 2024
Communications Physics

Volume: 7, P: 1-8
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

Patrick Gaffney and colleagues perform a fine-mapping study of the TNFAIP3 region in systemic lupus erythematosus using individuals from diverse ancestral populations. They identify a putative causal variant in a region of high conservation and regulatory potential that is associated with reduced TNFAIP3 expression.

Indra Adrianto
Feng Wen
Patrick M Gaffney
Research20 Feb 2011
Nature Genetics

Volume: 43, P: 253-258
Operative treatment as a part of the comprehensive care for patients with injuries of the thoracolumbar spine. A review

A Alho
Reviews01 Aug 1994
Spinal Cord

Volume: 32, P: 509-516
Accurate spectra for high energy ions by advanced time-of-flight diamond-detector schemes in experiments with high energy and intensity lasers

Martina Salvadori
F. Consoli
A. Zigler
ResearchOpen Access04 Feb 2021
Scientific Reports

Volume: 11, P: 1-16
Interferon-γ induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors

C E Egwuagu
W Li
A B Chepelinsky
Research06 Feb 2006
Oncogene

Volume: 25, P: 3670-3679
βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells

Shang et al. utilize a conditional Cryba1 knockout mouse model to demonstrate a key role for βA3/A1-crystallin in retinal pigmented epithelium. As a result of βA3/A1-crystallin deficiency, the authors report EGFR endocytosis defects and actin network disruption which leads to polarity disruption and degeneration through PITP β/PLC signaling.

Peng Shang
Nadezda Stepicheva
Debasish Sinha
ResearchOpen Access08 Jul 2021
Communications Biology

Volume: 4, P: 1-14
βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity

Ghosh et al. show that a lens protein βA1-crystallin inhibits PTP1B activity, regulating the metabolism of retinal astrocytes. They find that knockdown of βA1-crystallin exacerbates the streptozotocin-induced diabetic retinopathy-like phenotype in mice, suggesting the possibility that the interaction between βA1-PTP1B may be targeted for diabetic retinopathy.

Sayan Ghosh
Haitao Liu
Debasish Sinha
ResearchOpen Access24 Feb 2021
Communications Biology

Volume: 4, P: 1-19
Ultrafast evolution of electric fields from high-intensity laser-matter interactions

R. Pompili
M. P. Anania
A. Zigler
ResearchOpen Access19 Feb 2018
Scientific Reports

Volume: 8, P: 1-11
βA3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes

Mallika Valapala
Malia Edwards
Debasish Sinha
ResearchOpen Access04 Mar 2015
Scientific Reports

Volume: 5, P: 1-9
Slow evolution under purifying selection in the gamete recognition protein bindin of the sea urchin Diadema

L. B. Geyer
K. S. Zigler
H. A. Lessios
ResearchOpen Access17 Jun 2020
Scientific Reports

Volume: 10, P: 1-14
Neutrophils homing into the retina trigger pathology in early age-related macular degeneration

Ghosh et al. find that in a mouse model, age-related macular degeneration (AMD) is associated with retinal infiltration of neutrophils, activation of interferon lambda and production of other cytokines. They also see increased interferon lambda production in the eyes of AMD patients.

Sayan Ghosh
Archana Padmanabhan
Debasish Sinha
ResearchOpen Access20 Sept 2019
Communications Biology

Volume: 2, P: 1-17
Comparisons of simple and complex methods for quantifying exposure to individual point source air pollution emissions

Lucas R. F. Henneman
Irene C. Dedoussi
Corwin M. Zigler
Research17 Mar 2020
Journal of Exposure Science & Environmental Epidemiology

Volume: 31, P: 654-663
Beta-amyloid sequelae in the eye: a critical review on its diagnostic significance and clinical relevance in Alzheimer’s disease

T M Shah
S M Gupta
R N Martins
Reviews17 Jan 2017
Molecular Psychiatry

Volume: 22, P: 353-363
βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis

B Ma
T Sen
D Sinha
ResearchOpen Access13 Oct 2011
Cell Death & Disease

Volume: 2, P: e217
Effects of high-intensity interval training versus moderate-intensity continuous training on vascular function among individuals with overweight and obesity—a systematic review

Shishira K B
K. Vaishali
Tulasiram Bommasamudram
ReviewsOpen Access30 Jul 2024
International Journal of Obesity

Volume: 48, P: 1517-1533

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