Evidence for the effects of sex hormones on inflammation, myelination and neurodegeneration has implications for both cisgender and gender-diverse individuals with multiple sclerosis. Here, the authors summarize what is known about the effects of endogenous and exogenous sex hormones, and they highlight the need for future research inclusive of gender-diverse individuals.
- Cassie Nesbitt
- Anneke Van Der Walt
- Vilija G. Jokubaitis