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Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population

Jianjun Liu, Wei-Hua Jia, Adeline Seow, Dongxin Lin and colleagues report a genome-wide association study of B cell non-Hodgkin lymphoma in individuals of Chinese ancestry. They identify a new susceptibility locus on chromosome 3q27 in the intergenic region between BCL6 (B cell lymphoma protein 6) and LPP (lipoma preferred partner).

Dennis E K Tan
Jia Nee Foo
Jianjun Liu
Research09 Jun 2013
Nature Genetics

Volume: 45, P: 804-807
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans

The authors demonstrate the effectiveness of T cells in controlling acute viral infections, without neutralizing antibodies, by conducting an Orthoflavivirus vaccination and challenge study in humans.

Shirin Kalimuddin
Christine Y. L. Tham
Eng Eong Ooi
ResearchOpen Access10 Jan 2025
Nature Microbiology

Volume: 10, P: 374-387
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

SARS-CoV-2-reactive T cells were found in individuals who had recovered from SARS or COVID-19 and in unexposed donors, although with different patterns of immunoreactivity.

Nina Le Bert
Anthony T. Tan
Antonio Bertoletti
Research15 Jul 2020
Nature

Volume: 584, P: 457-462
Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Responses to SARS-CoV-2 vaccines in different populations are important to define efficacy. Here the authors show using a cohort in Singapore that two doses of mRNA vaccine is less effective in recipients over 60 years of age and that a further dose of vaccine can improve these antibody levels.

Laurent Renia
Yun Shan Goh
Lisa F. P. Ng
ResearchOpen Access08 Aug 2022
Nature Communications

Volume: 13, P: 1-16
Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn’s disease

Elodie Gimier
Mélissa Chervy
Jérémy Denizot
ResearchOpen Access31 Jul 2020
Scientific Reports

Volume: 10, P: 1-16
Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy

Qi Chen
Adeline Chia
Antonio Bertoletti
Research05 Sept 2023
Cellular & Molecular Immunology

Volume: 20, P: 1300-1312
Biomarker characterization of clinical subtypes of Parkinson Disease

Xiao Deng
Seyed Ehsan Saffari
Louis C. S. Tan
ResearchOpen Access29 Aug 2022
npj Parkinson's Disease

Volume: 8, P: 1-8
Building and Optimizing a Virus-specific T Cell Receptor Library for Targeted Immunotherapy in Viral Infections

Nasirah Banu
Adeline Chia
Adam J. Gehring
ResearchOpen Access25 Feb 2014
Scientific Reports

Volume: 4, P: 1-10

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Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population

Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn’s disease

Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy

Biomarker characterization of clinical subtypes of Parkinson Disease

Building and Optimizing a Virus-specific T Cell Receptor Library for Targeted Immunotherapy in Viral Infections

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