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Showing 1–11 of 11 results
Advanced filters: Author: Adrian Cazares Clear advanced filters

  • This Genome Watch discusses recent findings in bacterial mutational hotspots, their impact on pathogenesis and antimicrobial resistance, and how we can harness this knowledge to predict pathogen evolution.

    • Adrian Cazares
    • Daniel Cazares
    • Wendy Figueroa
    News
    Nature Reviews Microbiology
    Volume: 23, P: 621

  • Here, the authors describe the global distribution of crAssphage, its presence in Old-World and New-World primates, and its association with gut bacterial communities and dietary factors, providing insights into the origin, evolution and epidemiology of human gut crAssphage.

    • Robert A. Edwards
    • Alejandro A. Vega
    • Bas E. Dutilh
    Research
    Nature Microbiology
    Volume: 4, P: 1727-1736

  • The emergence of multidrug resistance (MDR) in bacteria represents a global threat to human health. Here, Cazares et al. identify a family of MDR megaplasmids carrying large arrays of antibiotic resistance genes in Pseudomonas strains from various sources, including P. aeruginosa clinical isolates.

    • Adrian Cazares
    • Matthew P. Moore
    • Craig Winstanley
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • This Genome Watch highlights how the revived interest in phages that target plasmid-carrying bacteria is expanding our knowledge of viral diversity, ecology and evolution, which is fundamental for developing safe biotherapeutics.

    • Daniel Cazares
    • Wendy Figueroa
    • Adrian Cazares
    News
    Nature Reviews Microbiology
    Volume: 22, P: 670

  • The genus Serratia includes clinically-important and diverse environmental bacteria. Here, Williams et al. assemble and analyse a representative set of 664 genomes from across the genus, including historic isolates, to provide a genome-based phylogenetic framework for a better understanding of the emergence of clinical and environmental lineages of Serratia.

    • David J. Williams
    • Patrick A. D. Grimont
    • Sarah J. Coulthurst
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18

  • This month’s Genome Watch highlights the systematic discovery of defence systems, paving the way to decode novel genetic functions and further our understanding of microbial warfare.

    • Adrian Cazares
    • Wendy Figueroa
    • Daniel Cazares
    News
    Nature Reviews Microbiology
    Volume: 20, P: 191

  • This Genome Watch discusses the use of metagenomic sequencing to investigate resistome dynamics in river ecosystems and their associations with the mobilome and microbiome, underscoring the role of rivers as reservoirs of antimicrobial resistance genes.

    • Onalenna Neo
    • Nisha Singh
    • Adrian Cazares
    News
    Nature Reviews Microbiology
    Volume: 23, P: 8

  • From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

    • Cristina Taddei
    • Bin Zhou
    • Majid Ezzati
    ResearchOpen Access
    Nature
    Volume: 582, P: 73-77