Nature Search

Holistic evaluation of large language models for medical tasks with MedHELM

MedHELM, an extensible evaluation framework including a new taxonomy for classifying medical tasks and a benchmark of many datasets across these categories, enables the evaluation of large language models on real-world clinical tasks.

Suhana Bedi
Hejie Cui
Nigam H. Shah
Research20 Jan 2026
Nature Medicine

P: 1-9
Simultaneous Occurrence of HÆmoglobins C and Lepore in an Afro-American

HELEN M. RANNEY
ALAN S. JACOBS
Research10 Oct 1964
Nature

Volume: 204, P: 163-166
Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1

Robert F. Paulson
Shirly Vesely
Alan Bernstein
Research01 Jul 1996
Nature Genetics

Volume: 13, P: 309-315
Nd, Sr and Pb isotopic systematics in a three-component mantle: a new perspective

Alan Zindler
Emil Jagoutz
Steven Goldstein
Research05 Aug 1982
Nature

Volume: 298, P: 519-523
Accumulation of Neural Activity in the Posterior Insula Encodes the Passage of Time

Marc Wittmann
Alan Simmons
Martin Paulus
ResearchOpen Access10 Jul 2008
Nature Precedings

P: 1
Drug-induced ocular cicatricial pemphigoid: A series of clinico-pathological reports

Zahida Butt
David Kaufman
Penny McKelvie
Research01 Mar 1998
Eye

Volume: 12, P: 285-290
Integrated intracellular organization and its variations in human iPS cells

A dataset of 3D images from more than 200,000 human induced pluripotent stem cells is used to develop a framework to analyse cell shape and the location and organization of major intracellular structures.

Matheus P. Viana
Jianxu Chen
Susanne M. Rafelski
ResearchOpen Access04 Jan 2023
Nature

Volume: 613, P: 345-354
Seeing new light

Alan E. Shapiro
Books & Arts24 May 1984
Nature

Volume: 309, P: 382-383
Researcher and Amgen baffled by Love letter

Alan Dove
Research01 Jun 1998
Nature Biotechnology

Volume: 16, P: 511
A redox-flow battery with an alloxazine-based organic electrolyte

Redox-flow batteries with organic-based electrolytes hold many advantages over conventional-flow batteries. Here the authors report a high-performance flow battery based on alloxazine, an aqueous-stable and soluble redox-active organic molecule resembling the backbone structure of vitamin B2.

Kaixiang Lin
Rafael Gómez-Bombarelli
Roy G. Gordon
Research18 Jul 2016
Nature Energy

Volume: 1, P: 1-8
The Need for Social Research

ALAN BLAIR
Research01 Dec 1934
Nature

Volume: 134, P: 898-899
Increasing the presence of BIPOC researchers in computational science

Nature Computational Science asked a group of scientists to discuss strategies for increasing the presence of Black, Indigenous, People of Color (BIPOC) researchers in computational science, as well as the various considerations to be made for improving education and methods design.

Christine Yifeng Chen
Alan Christoffels
Karaitiana Taiuru
Reviews24 Sept 2024
Nature Computational Science

Volume: 4, P: 646-653
Evaluation of electronic health record-integrated artificial intelligence chart review

Nicolas M. Kahl
Marshall J. Frieden
Alan X. You
ResearchOpen Access28 Jan 2026
npj Health Systems

Volume: 3, P: 1-4
Dr. W. T. Mathias

ALAN BURGES
Comments & Opinion26 Jun 1954
Nature

Volume: 173, P: 1211
Grasping the essentials

Alan Cowey
News & Views10 Jan 1991
Nature

Volume: 349, P: 102-103
Between fact and passion

Alan Cottrell
Books & Arts01 Aug 1985
Nature

Volume: 316, P: 583
An authoritarianism-compatible text changes British attitudes towards EU immigration

Tessa Buchanan
David J. Young
Lee de-Wit
ResearchOpen Access12 Sept 2025
Scientific Reports

Volume: 15, P: 1-8
Polygenic prediction of body mass index and obesity through the life course and across ancestries

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

Roelof A. J. Smit
Kaitlin H. Wade
Ruth J. F. Loos
ResearchOpen Access21 Jul 2025
Nature Medicine

Volume: 31, P: 3151-3168
Feeding Behaviour of the Praying Mantis: A Learned Modification

ALAN GELPERIN
Research01 Jul 1968
Nature

Volume: 219, P: 399-400
Primary uveal lymphoma mimicking uveitis with hypopyon

Alan Y. Hsu
Chun-Ju Lin
John Wang
Research11 Dec 2025
Eye

P: 1-2
Aurora and Thunderstorm

ALAN MACDOUGALL
Research06 Sept 1883
Nature

Volume: 28, P: 436
Correlation between Cloud Shade and Shedding in Cotton

ALAN GOODMAN
Research02 Jul 1955
Nature

Volume: 176, P: 39
Battle lines redrawn in BTWC debate

Alan Dove
Research01 Jan 1999
Nature Biotechnology

Volume: 17, P: 11-12
An apt approach

A new microbicide built from two types of RNA has shown promise against HIV in lab experiments, but moving it toward becoming a marketable product is proving difficult. Alan Dove investigates what's interfering with this novel therapeutic RNA strategy.

Alan Dove
News01 Mar 2010
Nature Medicine

Volume: 16, P: 258-260
Multiple bursts of speciation in Madagascar’s endangered lemurs

Here, the authors characterize the tempo and mode of lemur speciation with a phylogenomic dataset that also includes lorisiforms. They find that lemurs exhibited multiple bursts of diversification (without subsequent decline in diversification rate) with the highest diversification rates accompanied by high introgression rates.

Kathryn M. Everson
Luca Pozzi
David W. Weisrock
ResearchOpen Access01 Aug 2025
Nature Communications

Volume: 16, P: 1-15
Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3

Pierre Daubersies
Alan W. Thomas
Pierre Druilhe
Research01 Nov 2000
Nature Medicine

Volume: 6, P: 1258-1263
Evolutionary advantages of sex

Alan Robertson
Reviews09 Nov 1978
Nature

Volume: 276, P: 123-124
Historical portraits of the underdog

Alan Holland
Books & Arts19 Nov 1987
Nature

Volume: 330, P: 281-282
A case of polymyalgia rheumatica, microscopic polyangiitis, and B-cell lymphoma

Anoop Kuttikat
Andrew Keat
Kuntal Chakravarty
Reviews01 Dec 2006
Nature Clinical Practice Rheumatology

Volume: 2, P: 686-690
Combined oral and topical mesalazine treatment for extensive ulcerative colitis

Alan C Moss
Adam S Cheifetz
Mark A Peppercorn
Reviews01 May 2006
Nature Clinical Practice Gastroenterology & Hepatology

Volume: 3, P: 290-293
HIV-1 nuclear import is selective and depends on both capsid elasticity and nuclear pore adaptability

By developing a functional nuclear import system and correlative imaging workflow, this study reveals that HIV-1 nuclear entry relies on the elasticity of both the viral capsid and the nuclear pore to enable the selective passage of small HIV-1 cores.

Zhen Hou
Yao Shen
Peijun Zhang
ResearchOpen Access07 Jul 2025
Nature Microbiology

Volume: 10, P: 1868-1885
Blindsight in monkeys

Alan Cowey
Petra Stoerig
Research19 Jan 1995
Nature

Volume: 373, P: 247-249
Controlled steering of Cherenkov surface plasmon wakes with a one-dimensional metamaterial

Surface plasmon wakes can be created and steered using a one-dimensional metamaterial consisting of rotated nanoslits in which the phase velocity of a running wave of polarization propagates faster than the phase velocity of the surface plasmons.

Patrice Genevet
Daniel Wintz
Federico Capasso
Research06 Jul 2015
Nature Nanotechnology

Volume: 10, P: 804-809
The establishment and maintenance of pregnancy using in vitro fertilization and embryo donation in a patient with primary ovarian failure

Peter Lutjen
Alan Trounson
Peter Renou
Research12 Jan 1984
Nature

Volume: 307, P: 174-175
Icosahedra in aluminium / manganese alloy

ALAN L. MACKAY
Research20 Jun 1985
Nature

Volume: 315, P: 636
Mechanism of activation of HuBlym-1 gene unresolved (reply)

GEOFFREY M. COOPER
ALAN DIAMOND
Research22 May 1986
Nature

Volume: 321, P: 438-439
Choosing genes

Alan F. Wright
A. Christopher Boyd
Comments & Opinion26 Sept 1996
Nature

Volume: 383, P: 312
A fungal plant pathogen discovered in the Devonian Rhynie Chert

Here, the authors describe a pathogenic fungus from a 400-million-year-old fossil plant from the Devonian Rhynie Chert in Scotland. They use advanced imaging methods to determine that the fungus belongs to the sac fungi, the most diverse group of Fungi today.

Christine Strullu-Derrien
Tomasz Goral
David L. Hawksworth
ResearchOpen Access01 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Deconstructing the (un)affordability of clean cooking fuels through a randomized trial in rural Tanzania

Clean cooking fuels can be unaffordable. A year-long randomized control trial in Tanzania finds that a lockbox intervention along with behavioural nudging to encourage savings modestly increased liquefied petroleum gas use but did not lead to exclusive adoption, and that gendered financial constraints explain these results.

Annelise Gill-Wiehl
Isha Ray
Alan Hubbard
Research03 Jun 2025
Nature Energy

Volume: 10, P: 836-846
Spin–orbit torque-assisted switching in magnetic insulator thin films with perpendicular magnetic anisotropy

By virtue of strong spin-orbit coupling, a current-carrying heavy metal may generate a torque on the magnetization of an interfaced ferromagnetic metal. Here, the authors demonstrate how this effect assists the magnetic reversal of ferromagnetic insulators with perpendicular magnetic anisotropy.

Peng Li
Tao Liu
Mingzhong Wu
ResearchOpen Access01 Sept 2016
Nature Communications

Volume: 7, P: 1-8
Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models

T- and NK-cell lymphomas (TCL) are a group of lymphoid malignancies characterized by poor prognosis, but the absence of appropriate pre-clinical models has hampered the development of effective therapies. Here the authors establish several pre-clinical models and identify vulnerabilities that could be further exploited to treat patients afflicted by these diseases.

Samuel Y. Ng
Noriaki Yoshida
Raphael Koch
ResearchOpen Access22 May 2018
Nature Communications

Volume: 9, P: 1-11
Inherited venous beading

Bertrand Piguet
Mirjam Gross-Jendroska
Alan C Bird
Research01 Jan 1994
Eye

Volume: 8, P: 84-88
Protean muscle

Alan Weeds
News & Views15 Nov 1979
Nature

Volume: 282, P: 232-233
US views of British university research

A university researcher with long experience of British universities, but now working in the United States, reflects on the differences between the two systems and advocates modest reforms.

Alan R. Katritzky
Comments & Opinion01 Feb 1985
Nature

Volume: 313, P: 525-526
Growth Hormone Releasing Hormone and Growth Hormone: Genetic Studies in Familial Growth Hormone Deficiency

Alan D Rogol
Robert M Blizzard
Michael O Thorner
Research01 May 1985
Pediatric Research

Volume: 19, P: 489-492
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations

Polygenic risk scores can help identify individuals at higher risk of type 2 diabetes. Here, the authors characterise a multi-ancestry score across nearly 900,000 people, showing that its predictive value depends on demographic and clinical context and extends to related traits and complications.

Boya Guo
Yanwei Cai
Burcu F. Darst
ResearchOpen Access01 Oct 2025
Nature Communications

Volume: 16, P: 1-16
DNA microsatellite analysis of Dolly

David Ashworth
Matthew Bishop
Ian Wilmut
Research23 Jul 1998
Nature

Volume: 394, P: 329
Pattern recognition and active vision in chickens

Marian Stamp Dawkins
Alan Woodington
Research10 Feb 2000
Nature

Volume: 403, P: 652-655
An eyecare foundation model for clinical assistance: a randomized controlled trial

Trained and validated on multimodal data from 14.5 million images from multicountry datasets, a foundation model is shown to increase diagnostic and referral accuracy of clinicians when used as an assistant in a trial involving 16 ophthalmologists and 668 patients.

Yilan Wu
Bo Qian
Bin Sheng
Research28 Aug 2025
Nature Medicine

Volume: 31, P: 3404-3413
Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis

The authors identify mutations in the MATR3 gene as a cause of ALS and dementia in several families. MATR3 is known to bind the ALS-associated protein TDP-43, and at least one of these mutations alters the efficiency of this binding.

Janel O Johnson
Erik P Pioro
Bryan J Traynor
Research30 Mar 2014
Nature Neuroscience

Volume: 17, P: 664-666

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