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Showing 1–4 of 4 results
Advanced filters: Author: Alina Malita Clear advanced filters

  • Malita, Kubrak et al. show that the gut-derived hormone neuropeptide F suppresses sugar intake and increases the consumption of protein-rich food in Drosophila. This gives insight into the regulation of nutrient-specific appetite that ensures appropriate food choices to meet nutritional demands.

    • Alina Malita
    • Olga Kubrak
    • Kim Rewitz
    ResearchOpen Access
    Nature Metabolism
    Volume: 4, P: 1532-1550

  • Intestinal nutrient-sensing is important in metabolic control. Here the authors show that the gut-derived hormone Allatostatin C, a somatostatin homolog in fruit flies, links enteric nutrient sensing to behavioral and metabolic adaptations that maintain energetic homeostasis in Drosophila melanogaster.

    • Olga Kubrak
    • Takashi Koyama
    • Kim Rewitz
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17

  • The mechanisms by which organisms adapt their growth according to the availability of oxygen are incompletely understood. Here the authors identify the Drosophila fat body as a tissue regulating growth in response to oxygen sensing via a mechanism involving Hph inhibition, HIF1-a activation and insulin secretion.

    • Michael J. Texada
    • Anne F. Jørgensen
    • Kim F. Rewitz
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16