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Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Genome-wide association meta-analyses of attention-deficit/hyperactivity disorder symptom measures and clinical diagnoses identify new risk loci, highlight putative effector genes and yield improved polygenic risk scores.

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Research17 Sept 2025
Nature Genetics

Volume: 57, P: 2427-2435
Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Amendments and Corrections29 Sept 2025
Nature Genetics

Volume: 57, P: 2604
Dopamine D2 −141C Ins/Del and Taq1A polymorphisms, body mass index, and prediction error brain response

Guido K. W. Frank
Megan E. Shott
Andrew Smolen
ResearchOpen Access23 May 2018
Translational Psychiatry

Volume: 8, P: 1-7
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

Solid organ transplant recipients are at increased risk of infectious disease and have unique molecular pathophysiology. Here the authors use host-microbe profiling to assess SARS-CoV-2 infection and immunity in solid organ transplant recipients, showing enhanced viral abundance, impaired clearance, and increased expression of innate immunity genes.

Harry Pickering
Joanna Schaenman
Charles R. Langelier
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-16
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

The role of IgG glycosylation in the immune response has been studied, but less is known about IgM glycosylation. Here the authors characterize glycosylation of SARS-CoV-2 spike specific IgM and show that it correlates with COVID-19 severity and affects complement deposition.

Benjamin S. Haslund-Gourley
Kyra Woloszczuk
Mary Ann Comunale
ResearchOpen Access09 Jan 2024
Nature Communications

Volume: 15, P: 1-19
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Post-acute sequelae of SARS-CoV-2 (PASC) is still not well understood. Here the authors provide patient reported outcomes from 590 hospitalized COVID-19 patients and show association of PASC with higher respiratory SARS-CoV-2 load and circulating antibody titers, and in some an elevation in circulating fibroblast growth factor 21.

Al Ozonoff
Naresh Doni Jayavelu
Nadine Rouphael
ResearchOpen Access03 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Molecular characterization of colorectal cancer related peritoneal metastatic disease

Colorectal cancer can lead to the development of peritoneal metastases, which are associated with worse disease outcome. Here, the authors characterize peritoneal metastases from 52 patients using RNA-seq and mutational sequencing and show a distinct molecular subtype.

Kristiaan J. Lenos
Sander Bach
Louis Vermeulen
ResearchOpen Access04 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals

Richard Border
Andrew Smolen
Luke M. Evans
Research05 Feb 2019
European Journal of Human Genetics

Volume: 27, P: 963-969
Clocking in: chronobiology in rheumatoid arthritis

Circadian rhythms are well established as having an important role in human biology. In this Review, circadian biology is presented in reference to the regulation of rheumatoid arthritis and the potential for chronotherapeutic intervention.

Frank Buttgereit
Josef S. Smolen
Christian Cajochen
Reviews24 Mar 2015
Nature Reviews Rheumatology

Volume: 11, P: 349-356
Genetic association study of childhood aggression across raters, instruments, and age

Hill F. Ip
Camiel M. van der Laan
Dorret I. Boomsma
ResearchOpen Access30 Jul 2021
Translational Psychiatry

Volume: 11, P: 1-9
Olanzapine Reduces Craving for Alcohol: A DRD4 VNTR Polymorphism by Pharmacotherapy Interaction

Kent E Hutchison
Angela Wooden
Lyndee Paris
Research10 Jun 2003
Neuropsychopharmacology

Volume: 28, P: 1882-1888
Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile

Athena N. Nguyen
Alec L. Plotkin
Cissy Kityo
Research13 Jun 2023
Pediatric Research

Volume: 94, P: 1667-1674
The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI

Elizabeth K. Do
Brett C. Haberstick
Bernard F. Fuemmeler
Research22 Oct 2018
International Journal of Obesity

Volume: 43, P: 33-42

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