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Nature Structural & Molecular Biology (1)

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Structural basis for lipid transport at membrane contact sites by the IST2–OSH6 complex

IST2 serves as a tether between the endoplasmic reticulum and the plasma membrane in yeast. Here, Arndt et al. interrogate its interaction with OSH6, revealing that the two proteins remain associated during lipid shuttling.

Melanie Arndt
Angela Schweri
Raimund Dutzler
ResearchOpen Access27 Aug 2025
Nature Structural & Molecular Biology

P: 1-12

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Structural basis for lipid transport at membrane contact sites by the IST2–OSH6 complex

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