Large-scale approaches have linked protein phosphatase function to a multitude of nuclear processes, such as the DNA-damage response, cell-cycle progression and gene regulation. In addition, proteomics techniques have enabled the identification of new components of multiprotein phosphatase complexes, such as targeting and regulatory subunits.
- Greg B. G. Moorhead
- Laura Trinkle-Mulcahy
- Annegret Ulke-Lemée
