Nature Search

Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Publisher Correction: Tuned thalamic excitation is amplified by visual cortical circuits

Anthony D Lien
Massimo Scanziani
Amendments and Corrections16 Jul 2018
Nature Neuroscience

Volume: 21, P: 1292
ROR2 regulates self-renewal and maintenance of hair follicle stem cells

Wnt signaling functions in tissue homeostasis and tumorigenesis. Here the authors show that ROR2, a Wnt receptor, plays roles not only in transducing Wnt signaling, but also in regulation of DNA damage response critical for stem cell maintenance.

Anthony Veltri
Christopher M. R. Lang
Wen-Hui Lien
ResearchOpen Access01 Aug 2022
Nature Communications

Volume: 13, P: 1-17
Cortical direction selectivity emerges at convergence of thalamic synapses

Direction selectivity emerges de novo in layer 4 neurons of primary visual cortex through the convergence of synaptic inputs from thalamic neurons that respond with distinct time courses to visual stimuli in distinct locations.

Anthony D. Lien
Massimo Scanziani
Research23 May 2018
Nature

Volume: 558, P: 80-86
Observation of quantum entanglement with top quarks at the ATLAS detector

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s = 13 TeV and an integrated luminosity of 140 fb⁻¹.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access18 Sept 2024
Nature

Volume: 633, P: 542-547
A randomized, non-comparative phase 2 study of neoadjuvant immune-checkpoint blockade in retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma

Roland et al. report the results of a randomized, non-comparative phase 2 trial of neoadjuvant nivolumab or a combination of nivolumab and ipilimumab in patients with resectable retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma.

Christina L. Roland
Elise F. Nassif Haddad
Neeta Somaiah
Research13 Feb 2024
Nature Cancer

Volume: 5, P: 625-641
Tuned thalamic excitation is amplified by visual cortical circuits

Using optogenetics to silence the cortex, the authors show that thalamic inputs to layer 4 V1 neurons in anesthetized mice only contribute a third of the total excitation to these cells during presentation of visual stimuli. Moreover, they find that a small offset in the center of ON and OFF receptive subfields accounts for the orientation tuning of thalamic excitation to these cells.

Anthony D Lien
Massimo Scanziani
Research11 Aug 2013
Nature Neuroscience

Volume: 16, P: 1315-1323
Quantum sensing for gravity cartography

A study reports a quantum gravity gradient sensor with a design that eliminates the need for long measurement times, and demonstrates the detection of an underground tunnel in an urban environment.

Ben Stray
Andrew Lamb
Michael Holynski
ResearchOpen Access23 Feb 2022
Nature

Volume: 602, P: 590-594
Risk-stratified treatment for drug-susceptible pulmonary tuberculosis

Authors perform an analysis of the patient data and risk factors to evaluate unfavorable outcomes and adverse events in adults with pulmonary tuberculosis treated with a 4-month rifapentine based regimen. Low rifapentine exposure was the most clinically significant risk factor for treatment failure and tuberculosis relapse.

Vincent K. Chang
Marjorie Z. Imperial
Elizabeth Guy
ResearchOpen Access30 Oct 2024
Nature Communications

Volume: 15, P: 1-12
À la recherche d'un vaccin contre la leishmaniose

Les chercheurs espèrent que la vaccination fournira une protection indispensable contre cette maladie parasitaire négligée dans les zones de conflit.

Anthony King
News25 Aug 2023
Nature Africa
Immuno-genomic landscape of osteosarcoma

The efficacy of immune checkpoint inhibitors (ICI) in osteosarcoma has been limited. Here, the authors investigate the immunogenomic landscape of osteosarcoma, and integrated analyses highlight features related to a suppressed immune microenvironment.

Chia-Chin Wu
Hannah C. Beird
P. Andrew Futreal
ResearchOpen Access21 Feb 2020
Nature Communications

Volume: 11, P: 1-11
Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

Nonreceptor guanine-nucleotide exchange factors (GEFs) are emerging as important regulators of heterotrimeric G proteins. Here, the authors present structural and mechanistic insights into how a class of nonreceptor GEFs containing the Ga-Binding and Activating motif interact and modulate G proteins.

Alain Ibáñez de Opakua
Kshitij Parag-Sharma
Mikel Garcia-Marcos
ResearchOpen Access18 May 2017
Nature Communications

Volume: 8, P: 1-16
Author Correction: Risk-stratified treatment for drug-susceptible pulmonary tuberculosis

Vincent K. Chang
Marjorie Z. Imperial
Elizabeth Guy
Amendments and CorrectionsOpen Access13 May 2025
Nature Communications

Volume: 16, P: 1
Distinct recurrent versus afferent dynamics in cortical visual processing

By optogenetically silencing thalamus, the authors show that visual cortex does not sustain a response without thalamus for more than a few tens of milliseconds. This rapid cortical activity decay predicts the temporal dynamics of sensory activity transmission between thalamus and cortex in awake animals, whereas under anesthesia, the fidelity of thalamo-cortical connection is dominated by the effect of synaptic depression.

Kimberly Reinhold
Anthony D Lien
Massimo Scanziani
Research26 Oct 2015
Nature Neuroscience

Volume: 18, P: 1789-1797
Treatment patterns, efficacy and toxicity of regorafenib in gastrointestinal stromal tumour patients

Gustavo Schvartsman
Michael J. Wagner
Neeta Somaiah
ResearchOpen Access25 Aug 2017
Scientific Reports

Volume: 7, P: 1-7
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
TOLLing away in Brazil

Toll 2006, Recent Advances in Pattern Recognition, held in Salvador, Brazil, 4–7 March 2006, was both comprehensive and cutting edge, covering topics ranging from molecular recognition and signaling to new therapies in the clinic.

Jane A Mitchell
Katherine A Fitzgerald
Neil Cartwright
News & Views01 Jul 2006
Nature Immunology

Volume: 7, P: 675-679
Topographic effect on the phenology of Ficus pedunculosa var. mearnsii (Mearns fig) in its northern boundary distribution, Taiwan

Chu-Chia Kuo
Anthony Bain
Hsy-Yu Tzeng
ResearchOpen Access07 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas

Anthony N Karnezis
Lien N Hoang
Cheng-Han Lee
Research08 Jan 2016
Modern Pathology

Volume: 29, P: 302-314
Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas

Mackenzie Coatham
Xiaodong Li
Cheng-Han Lee
Research26 Aug 2016
Modern Pathology

Volume: 29, P: 1586-1593
AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach
Denzil Bernard
Abraham Heifets
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-16
Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder

John W. Scott
Elizabeth Park
Bruce E. Kemp
ResearchOpen Access23 Sept 2015
Scientific Reports

Volume: 5, P: 1-10
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Khalid El Bairi
Harry R. Haynes
Paul J. Van Diest
ReviewsOpen Access01 Dec 2021
npj Breast Cancer

Volume: 7, P: 1-17
Author Correction: AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach
Denzil Bernard
Ellie Giles
Amendments and CorrectionsOpen Access16 Sept 2024
Scientific Reports

Volume: 14, P: 1-2

Search

Diminishing benefits of urban living for children and adolescents’ growth and development

Publisher Correction: Tuned thalamic excitation is amplified by visual cortical circuits

ROR2 regulates self-renewal and maintenance of hair follicle stem cells

Cortical direction selectivity emerges at convergence of thalamic synapses

Observation of quantum entanglement with top quarks at the ATLAS detector

A randomized, non-comparative phase 2 study of neoadjuvant immune-checkpoint blockade in retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma

Tuned thalamic excitation is amplified by visual cortical circuits

Quantum sensing for gravity cartography

Risk-stratified treatment for drug-susceptible pulmonary tuberculosis

À la recherche d'un vaccin contre la leishmaniose

Immuno-genomic landscape of osteosarcoma

Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif

Author Correction: Risk-stratified treatment for drug-susceptible pulmonary tuberculosis

Distinct recurrent versus afferent dynamics in cortical visual processing

Treatment patterns, efficacy and toxicity of regorafenib in gastrointestinal stromal tumour patients

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

TOLLing away in Brazil

Topographic effect on the phenology of Ficus pedunculosa var. mearnsii (Mearns fig) in its northern boundary distribution, Taiwan

Loss of switch/sucrose non-fermenting complex protein expression is associated with dedifferentiation in endometrial carcinomas

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas

AI is a viable alternative to high throughput screening: a 318-target study

Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Author Correction: AI is a viable alternative to high throughput screening: a 318-target study

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