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Showing 1–4 of 4 results
Advanced filters: Author: Anton M. Schüle Clear advanced filters

  • Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces tumour-specific immunity and identified potential therapeutic targets.

    • Brian M. Andersen
    • Camilo Faust Akl
    • Francisco J. Quintana
    Research
    Nature
    Volume: 644, P: 1097-1106

  • A population of TRAIL-positive astrocytes in glioblastoma contributes to an immunosuppressive tumour microenvironment and this mechanism can be targeted with an engineered oncolytic virus to improve outcomes.

    • Camilo Faust Akl
    • Brian M. Andersen
    • Francisco J. Quintana
    Research
    Nature
    Volume: 643, P: 219-229

  • Inflammatory monocytes in the brain meninges promote stress-induced fear behaviour, and the pathways involved can be modulated using psychedelic compounds.

    • Elizabeth N. Chung
    • Jinsu Lee
    • Michael A. Wheeler
    Research
    Nature
    Volume: 641, P: 1276-1286

  • How sensory maps are formed in the brain is only partially understood. Here the authors describe spontaneous calcium waves that propagate across different sensory nuclei in the embryonic thalamus; disrupting the wave pattern triggers thalamic gene expression changes and eventually alters the size of cortical areas.

    • Verónica Moreno-Juan
    • Anton Filipchuk
    • Guillermina López-Bendito
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14