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Showing 1–6 of 6 results

Advanced filters: Author: Anwen Liu Clear advanced filters

First-line sacituzumab tirumotecan with tagitanlimab in advanced non-small-cell lung cancer: a phase 2 trial

In the multicenter phase 2 OptiTROP-Lung01 trial in patients with treatment-naive advanced non-small-cell lung cancers, the antibody–drug conjugate sacituzumab tirumotecan with anti-PD-L1 tagitanlimab was safe and showed encouraging clinical efficacy.

Shaodong Hong
Qiming Wang
Wenfeng Fang
Research19 Aug 2025
Nature Medicine

P: 1-8
D3S-001 in advanced solid tumors with KRAS^G12C mutations: a phase 1 trial

As presented at the 2025 AACR Annual Meeting, in an ongoing first-in-human phase 1 trial of a next-generation KRAS-G12C inhibitor in patients with solid tumors, encouraging safety and response results were observed, including in patients with non-small-cell lung cancer.

Byoung Chul Cho
Shun Lu
Tony Mok
Research29 Apr 2025
Nature Medicine

Volume: 31, P: 2768-2777
First-in-human, phase 1 dose-escalation and dose-expansion study of a RET inhibitor SY-5007 in patients with advanced RET-altered solid tumors

Wei Li
Yongsheng Wang
Caicun Zhou
ResearchOpen Access04 Nov 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-11
Finite-temperature screw dislocation core structures and dynamics in α-titanium

Anwen Liu
Tongqi Wen
David J. Srolovitz
ResearchOpen Access21 Dec 2023
npj Computational Materials

Volume: 9, P: 1-13
Intake of high sucrose during pregnancy altered large-conductance Ca²⁺-activated K⁺ channels and vessel tone in offspring’s mesenteric arteries

Shigang Li
Qi Fang
Zhice Xu
Research27 Sept 2012
Hypertension Research

Volume: 36, P: 158-165
The long non-coding RNA uc.4 influences cell differentiation through the TGF-beta signaling pathway

Zijie Cheng
Qijun Zhang
Lingmei Qian
ResearchOpen Access16 Feb 2018
Experimental & Molecular Medicine

Volume: 50, P: e447