Foetal haematopoiesis takes place in the liver before the bone marrow is seeded. Here the authors used imaging analysis and mouse genetics to look at nascent bone marrow formation and show that yolk-sac-derived myeloid cells promote haematopoiesis by promoting specification of a VCAM1+ sinusoidal colonisation niche.
- Benjamin Weinhaus
- Shelli Homan
- Daniel Lucas
