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Showing 1–5 of 5 results
Advanced filters: Author: Avradip Chatterjee Clear advanced filters

  • CUT and HOX are conserved DNA binding elements prevalent in human transcription factors. Here, the authors use an integrative approach to study the mechanism of CUT-HOX cross-talk towards DNA binding by the prostate cancer target ONECUT2.

    • Avradip Chatterjee
    • Brad Gallent
    • Ramachandran Murali
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • Cutibacterium acnes phylotypes can be catalogued based on their association with acneic or healthy skin. Here, Hajam et al show that the functional divergence of a hyaluronidase enzyme expressed by the phylotypes is a major determinant of acne severity.

    • Irshad A. Hajam
    • Madhusudhanarao Katiki
    • George Y. Liu
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Ionizing radiation and chemotherapy deplete haematopoietic stem cells and damage the vascular niche. Here the authors show that irradiation induces SEMA3A secretion from bone marrow endothelial cells (ECs), inducing EC apoptosis via NRP1 and that NRP1 inhibition promotes vascular regeneration and R spondin 2 dependent hematopoietic regeneration.

    • Christina M. Termini
    • Amara Pang
    • John P. Chute
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-17