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Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans

The authors demonstrate the effectiveness of T cells in controlling acute viral infections, without neutralizing antibodies, by conducting an Orthoflavivirus vaccination and challenge study in humans.

Shirin Kalimuddin
Christine Y. L. Tham
Eng Eong Ooi
ResearchOpen Access10 Jan 2025
Nature Microbiology

Volume: 10, P: 374-387
Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine

Eugenia Z. Ong
Jia Xin Yee
Kuan Rong Chan
ResearchOpen Access28 Nov 2022
npj Vaccines

Volume: 7, P: 1-9
A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine

Jenny G. Low
Ruklanthi de Alwis
Eng Eong Ooi
ResearchOpen Access13 Dec 2022
npj Vaccines

Volume: 7, P: 1-9
Molecular determinants of plaque size as an indicator of dengue virus attenuation

Kenneth Choon Meng Goh
Choon Kit Tang
Eng Eong Ooi
ResearchOpen Access17 May 2016
Scientific Reports

Volume: 6, P: 1-11