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Showing 1–5 of 5 results
Advanced filters: Author: Azfar G Zaman Clear advanced filters

  • In a randomized trial of patients with a previous myocardial infarction and with residual inflammation, a monoclonal antibody targeting the LOX-1 receptor, thought to contribute to atherosclerotic plaque progression and inflammation, reduced soluble LOX-1 and interleukin-6 levels but did not lead to a substantial reduction in coronary plaque volume.

    • Michelle L. O’Donoghue
    • David A. Morrow
    • Marc S. Sabatine
    Research
    Nature Medicine
    Volume: 31, P: 3553-3559

  • The current treatment for patients receiving coronary stents is dual antiplatelet therapy. Approximately 5% of these patients, however, require long-term anticoagulation because of an underlying chronic medical therapy and, theoretically, should receive triple therapy, which increases bleeding risk. Here, Helft et al. critically appraise the available literature concerning antithrombotic therapy and make recommendations for antiplatelet therapy following revascularization in the small subset of patients already receiving anticoagulation.

    • Gérard Helft
    • Martine Gilard
    • Azfar G Zaman
    Reviews
    Nature Clinical Practice Cardiovascular Medicine
    Volume: 3, P: 673-680

  • Thyroid hormones have an important role in maintaining cardiovascular homeostasis, and subtle changes in thyroid hormone concentrations adversely influence the cardiovascular system. In this Review, Jabbar et al. discuss the role of thyroid hormones in the pathogenesis and management of cardiovascular diseases such as heart failure and acute myocardial infarction, and outline the utility of therapy with thyroid hormones for the management of these conditions.

    • Avais Jabbar
    • Alessandro Pingitore
    • Salman Razvi
    Reviews
    Nature Reviews Cardiology
    Volume: 14, P: 39-55