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Bright light reduces feeding and weight gain in mice by activating a specific retina-to-brain pathway that signals through the visual thalamus to inhibit appetite-regulating neurons in the hypothalamus.

Controlling electron spin states with light is vital for quantum technologies but requires electronic excitations with net spin. Now a molecular diradical with two trityl radical groups coupled via a meta-linked fluorene bridge has been developed that features luminescent singlet and triplet excitons. The spins in the ground state can be written and read using photons, giving rise to broad magnetic and microwave modulation of the photoluminescence.

It has been show that monolayer transition metal dichalcogenides exhibit tightly bound excitons with a valley pseudospin that can be optically addressed by polarization selection rules. Here, the authors show the valley pseudospin is strongly coupled to the exciton centre-of-mass motion through electron-hole exchange.

In this work, the authors demonstrate nonlinearity-engineered dissipative quadratic solitons (DQS) for the first time. Moreover, they achieve an in-situ sign reversal of the effective nonlinearity, enabling a transition from bright DQS to platicon generation without requiring any dispersion engineering.

Yellow fluorescent proteins (YFPs) photobleach rapidly, restricting microscopy experiments. Here, the authors report mGold2s and mGold2t, YFPs that extend imaging durations up to 25 times longer than standard probes without sacrificing brightness.

Indium tin oxide, the predominant material used as transparent electrodes in organic LEDs, is expensive and brittle. Ning Li and colleagues form transparent electrodes using single-layer graphene to construct organic LEDs with unprecedented performance that are suitable for both displays and lighting.

Atomically thin monolayers with high photoluminescence quantum yield are promising for optoelectronic and lighting applications. Here, the authors fabricate a transient-mode electroluminescent device to bypass the requirement of ohmic contacts for electrons and holes, and observe millimetre-scale light emission from a transparent 2D display.

Here the authors map the dynamics of human NK cell residency and recirculation, showing that CD56^bright NK cells transiently occupy tissues and recirculate via lymphatics, whereas CD56^dim NK cells remain vascular except during inflammation.

Most NIR radiation absorbers used in multi jet fusion 3D printing have an intrinsic dark color which prevents printing parts with variable colors. Here, the authors design an activating fusing agent containing a strong NIR absorbing dye that turns colorless after harvesting irradiation energy during the 3D printing process and provide a bright colored part when working with other color agents.

Proper exposure settings are crucial for modern machine vision cameras. This work develops neuromorphic exposure control using peripheral-vision inspired processing to solve the problem, enhancing performance in applications like autonomous driving and medical imaging.

Repeating fast radio burst, FRB 20200120E, has been localized to a globular cluster M81. Here, the authors show detection of a burst from FRB 20200120E that is 42 times stronger than the previously detected bursts.

New fully integrated semiconductor laser architectures are shown to be able to generate bright and background-free picosecond solitons at GHz repetition rates in the mid-infrared range.

Controlling the intrinsic doping of lead-free perovskites enables near-infrared LEDs emitting at 948 nm with a peak radiance of 226 W sr^–1 m^–2 and a half-lifetime of 39.5 h.

A long-period radio transient with coincident radio and X-ray emission and observational properties unlike any known Galactic object has been observed by the Australian Square Kilometre Array Pathfinder.

Self-DNA has been implicated in the activation of cGAS/STING/IFN-I responses in autoimmunity and inflammatory diseases. Here the authors show that macrophage uses a process termed ‘nucleocytosis’ to extract nuclear DNA from lysosome-impaired, dying target cells, thereby activating downstream cGAS-STING signaling and IFN-I production.

A Kerr-nonlinear resonator with normal dispersion supports bright and dark pulse states. With photonic crystal ring resonators, this work demonstrates a continuum across these nonlinear states and explores the underlying mechanism.

Observations of six transiting planets around the bright nearby star HD 110067 show that they follow a chain of resonant orbits, with three of the planets inferring the presence of large hydrogen-dominated atmospheres.

Fano-resonant nanostructures have received interest in the sensing community due to the high local fields and narrow resonant linewidths. Here, the authors characterise subwavelength perturbations in a Fano-resonant dielectric metasurface using both a conventional spectral method and a Fourier scatterometry approach, demonstrating that perturbations induce pronounced directional scattering in Fourier space.

The use of luminescence, rather than fluorescence, for imaging is advantageous in situations where laser illumination should be avoided. Here the authors make five colour variants of bright luminescent proteins based on FRET between NLuc and fluorescent proteins, and show their utility as Ca²⁺indicators.

Pulsar timing measurements show a mass ratio of about 0.8 for the double neutron-star system PSR J1913+1102, and population synthesis models indicate that such asymmetric systems represent 2–30% of merging binaries.

Viral ribonucleoprotein–viral protein networks form pre-replication centres that nucleate viral factories and drive respiratory syncytial virus replication.

A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and organic signatures that warrant consideration as potential biosignatures.

Atoms can be used as highly sensitive magnetic-field sensors. By exploiting the effects of electric fields on the optical transitions of excited Rydberg states, it is now demonstrated that it is also possible to probe very weak microwave electric fields with atoms.

Measurements of an intense radio burst from a Galactic magnetar provide evidence that magnetars are the probable source of some fast radio bursts.

Multidentate molecular additives are widely used to passivate perovskite, yet the role of chelate effect is still unclear. Here, the authors investigate a wide range of additives with different coordination number and functional moieties to establish correlation between coordination affinity and perovskite crystallisation dynamics.

The γ-ray burst GRB 200415A is probably a giant flare emitted from a magnetar in the nearby starburst galaxy NGC 253.

By studying fossil corals on Ishigaki Island in Japan, Debaecker et al. find evidence of repeating megathrust earthquakes over the last 5,000 years, revealing long-term earthquake supercycles and highlighting significant future earthquake and tsunami hazards.

Mucosal administration of a multivalent, adjuvanted vaccine against Clostridioides difficile promoted bacterial clearance and protected against morbidity, mortality, tissue damage and recurrence in mice.

The dwarf planet (1) Ceres, the largest object in the main asteroid belt, is found to have localized bright areas on its surface; particularly interesting is a bright pit on the floor of the crater Occator that exhibits what is likely to be water ice sublimation, producing crater-bound haze clouds with a diurnal rhythm.

In vivo imaging is facilitated by a bright, cyan-excitable orange fluorescent protein that is the basis of an improved bioluminescent protein.

A new ultraluminous X-ray source has been discovered in M 31, whose variability and associated bright, compact radio emission identify it as a stellar-mass black hole accreting close to the Eddington limit.

The electronic behaviour of complex oxides such as LaNiO₃ depends on many intrinsic and extrinsic factors, making it challenging to identify microscopic mechanisms. Here the authors demonstrate the influence of oxygen vacancies on the thickness-dependent metal-insulator transition of LaNiO₃ films.

Betratron oscillations of electrons driven through a plasma by a high-intensity laser generate coherent X-rays. A new study demonstrates the intensity of these X-rays can be as bright as that generated by conventional third-generation synchrotrons, in a device a fraction of the size and cost.

Organic molecular crystals with controllable bending angles are crucial interconnectors in integrated optoelectronic chips but current methods of tailoring bent geometric features in molecular crystals without fracturing remain limited. Here the authors proposing a molecular cocrystal strategy that introduces directional non-covalent interactions into molecular systems to weaken the original interactions triggering the spontaneous deformation.

The transcription factor ATF4 and its effector lipocalin 2 (LCN2) have a key role in immune evasion and tumour progression, and targeting the ATF4–LCN2 axis might provide a way to treat several types of solid tumour by increasing anti-cancer immunity.

Drug-controlled DROP-CARs enable reversible extracellular control of CAR T cell function via human-derived protein switches that modulate cell–cell interactions and support dual-antigen targeting as well as logic-gated signaling.

Native crystallographic defects are often introduced during synthesis of battery materials, but has been overlooked. Here, using in situ synchrotron X-ray probes and electron microscopy, the authors have revealed their adverse effect during battery operation.

In this study, the authors present optimization and efficacy testing of apolipoprotein-based lipid nanoparticles for delivering various nucleic acid therapeutics in vivo to immune cells and their progenitors in the bone marrow.

Deep optical observations of GRB 060614 show no emerging supernova with absolute magnitude brighter than M_V = − 13.7. Any supernova associated with GRB 060614 was therefore at least 100 times fainter, at optical wavelengths, than the other supernovae associated with GRBs.

Upconverting nanoparticles smaller than 10 nm are brighter when excited under single-particle conditions than when they are part of an ensemble.

Natural killer (NK) cells are important innate immune cells with diverse functions. Here the authors use single-cell RNA-sequencing of purified human bone marrow and peripheral blood NK cells to define five populations of NK cells with distinct transcriptomic profile to further our understanding of NK development and heterogeneity.