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Showing 1–50 of 61 results

Advanced filters: Author: B Perumal Clear advanced filters

Correlative imaging integrates electrophysiology with three-dimensional murine heart reconstruction to reveal electrical coupling between cell types

Giardini et al. present an imaging method that combines quantitative measurements of cardiac electrophysiology with high-resolution three-dimensional structural reconstructions, enabling the detection of arrhythmogenic electrical coupling between cardiomyocytes and non-myocytes in murine hearts.

Francesco Giardini
Camilla Olianti
Leonardo Sacconi
ResearchOpen Access06 Oct 2025
Nature Cardiovascular Research

P: 1-21
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Mechanical performance and predictive tribological modeling of Al7075 composites reinforced with rice hull activated carbon

Swapna Banoth
Suresh Babu Valasingam
Perumal Asaithambi
ResearchOpen Access10 Oct 2025
Scientific Reports

Volume: 15, P: 1-19
Mummification in a Bitch: A case report

Perumal P
Venkateswaralu B
P.C. Mishra
ResearchOpen Access02 Apr 2012
Nature Precedings

P: 1
Seasonal biological social and cognitive mechanisms of mental health among Chinese adolescents

Ran Chai
Jiaxiang Guo
Xinding Yao
ResearchOpen Access26 Sept 2025
Scientific Reports

Volume: 15, P: 1-10
Differential impacts of regenerative agriculture practices on soil organic carbon: a meta-analysis of studies from India

Mukund Patil
Cuba Perumal
Ramesh Singh
ResearchOpen Access29 Sept 2025
Scientific Reports

Volume: 15, P: 1-13
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

Damaris Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access12 Oct 2021
Nature Medicine

Volume: 27, P: 1761-1782
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
In-vitro assessment of anti-breast cancer potential of pumpkin seed oil nanoemulsion with mechanistic insights into cytotoxicity and apoptosis

Rupali Ghosh
Noor Fatima
Saima Wajid
ResearchOpen Access30 Jul 2025
Scientific Reports

Volume: 15, P: 1-20
Sensitive detection of dengue serotype-4 on lignin-derived graphene nanofibre and manganese oxide composite by DNA-sensing

Sivainesh Devi Remesh
Saravanan Karuppanan
Raju Suresh Kumar
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000–2018

Bhattacharjee and Schaeffer et al. map exclusive breastfeeding (EBF) in 94 low- and middle-income countries (LMICs), finding increased EBF practice and reduced subnational variation across the majority of LMICs from 2000 to 2018. However, only six LMICs will meet WHO’s target of ≥70% EBF by 2030 nationally, and only three will achieve this in all districts.

Natalia V. Bhattacharjee
Lauren E. Schaeffer
Simon I. Hay
ResearchOpen Access03 Jun 2021
Nature Human Behaviour

Volume: 5, P: 1027-1045
The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes

Brassica oleracea is plant species comprising economically important vegetable crops. Here, the authors report the draft genome sequence of B. oleracea and, through a comparative analysis with the closely related B. rapa, reveal insights into Brassicaevolution and divergence of interspecific genomes and intraspecific subgenomes.

Shengyi Liu
Yumei Liu
Andrew H Paterson
ResearchOpen Access23 May 2014
Nature Communications

Volume: 5, P: 1-11
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Evidence that the Acute Behavioral and Electrophysiological Effects of Bupropion (Wellbutrin®) Are Mediated by a Noradrenergic Mechanism

Barrett R. Cooper
Ching M. Wang
Robert M. Ferris
Research01 Oct 1994
Neuropsychopharmacology

Volume: 11, P: 133-141
Bioinformatics-driven discovery of skin microbiota bacteriocins as potential antibiotics and probiotics

Anum Munir
Alan Janbey
Marriam Bakhtiar
Research24 Jul 2025
The Journal of Antibiotics

Volume: 78, P: 606-620
Metaparameter optimized hybrid deep learning model for next generation cybersecurity in software defined networking environment

C. Labesh Kumar
Suresh Betam
Bhawani Sankar Panigrahi
ResearchOpen Access23 Apr 2025
Scientific Reports

Volume: 15, P: 1-22
Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy

Combined methylmalonic acidemia (MMA) and hyperhomocysteinemias are inborn errors of vitamin B12 metabolism, and mutations in the transcriptional regulators HCFC1 and RONIN (THAP11) underlie some forms of these disorders. Here the authors generated mouse models of a human syndrome due to mutations in RONIN (THAP11) and HCFC1, and show that this syndrome is both an inborn error of vitamin B12 metabolism and displays some features of ribosomopathy.

Tiffany Chern
Annita Achilleos
Ross A. Poché
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-21
ABCE1 facilitates tumour progression via aerobic glycolysis and inhibits cell death in human colorectal cancer cells through the p53 signalling pathway

Sathan Raj Natarajan
Rajapandiyan Krishnamoorthy
Selvaraj Jayaraman
ResearchOpen Access09 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
Impact of simulated acid rain on chemical properties of Nyalau series soil and its leachate

Mohamad Hilmi Ibrahim
Susilawati Kasim
Md. Tariqul Islam Shajib
ResearchOpen Access12 Feb 2024
Scientific Reports

Volume: 14, P: 1-11
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

This study uses gene expression predictors for the dorsolateral prefrontal cortex and other brain regions to perform a transcriptomic imputation analysis of schizophrenia, identifying 413 genic associations across 13 brain regions and 36 significantly enriched pathways.

Laura M. Huckins
Amanda Dobbyn
Eli A. Stahl
Research25 Mar 2019
Nature Genetics

Volume: 51, P: 659-674
Green synthesis of zinc oxide nanoparticles using aqueous extract of shilajit and their anticancer activity against HeLa cells

Parthasarathi Perumal
Nazeer Ahamed Sathakkathulla
Suresh Rathinasamy
ResearchOpen Access25 Jan 2024
Scientific Reports

Volume: 14, P: 1-11
Functional annotation of rare structural variation in the human brain

Structural variants (SVs) contribute to the genetic architecture of many brain-related disorders. Here, the authors integrate SV calls from genome sequencing (n = 755) with RNA-seq data (n = 629) from post-mortem dorsal lateral prefrontal cortex to annotate the gene regulatory effects of SVs in the human brain and their potential to contribute to disease.

Lide Han
Xuefang Zhao
Douglas M. Ruderfer
ResearchOpen Access12 Jun 2020
Nature Communications

Volume: 11, P: 1-13
Genetic and Pharmacological Modulation of the Steroid Sulfatase Axis Improves Response Control; Comparison with Drugs Used in ADHD

William Davies
Trevor Humby
Lawrence S Wilkinson
Research20 May 2014
Neuropsychopharmacology

Volume: 39, P: 2622-2632
EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis

Enhancer of zeste homolog 2 (EZH2) has been associated with poor prognosis in triple negative breast cancer (TNBC). Here, the authors suggest a potential role for trimethylation function of EZH2 in driving peritoneal metastasis in TNBC.

Ayushi Verma
Akhilesh Singh
Dipak Datta
ResearchOpen Access29 Nov 2022
Nature Communications

Volume: 13, P: 1-22
Risk factors for the development of triple-negative breast cancer versus non-triple-negative breast cancer: a case–control study

Shona Nag
Rajesh Dikshit
Sudeep Gupta
ResearchOpen Access20 Aug 2023
Scientific Reports

Volume: 13, P: 1-7
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

Interleukin 9 secretion contributes to allergic inflammation. Kaplan and colleagues identify the transcription factor PU.1 as being necessary for T_H9 differentiation and as a contributing factor in allergic airway inflammation.

Hua-Chen Chang
Sarita Sehra
Mark H Kaplan
Research02 May 2010
Nature Immunology

Volume: 11, P: 527-534
Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia

Breen et al. map RNA editing profiles in cortical samples from individuals with schizophrenia and controls, and find links between altered RNA editing in glutamatergic and postsynaptic density genes and schizophrenia genetic risk architecture.

Michael S. Breen
Amanda Dobbyn
Elizabeth Zharovsky
Research27 Aug 2019
Nature Neuroscience

Volume: 22, P: 1402-1412
Statistical assessment of reliability of anthropometric measurements in the multi-site South African National Dietary Intake Survey 2022

Sanja Nel
Jeroen de Man
Friedeburg Anna Maria Wenhold
ResearchOpen Access14 May 2024
European Journal of Clinical Nutrition

Volume: 78, P: 1005-1013
‘Spotted Nanoflowers’: Gold-seeded Zinc Oxide Nanohybrid for Selective Bio-capture

Veeradasan Perumal
U. Hashim
P. Poopalan
ResearchOpen Access16 Jul 2015
Scientific Reports

Volume: 5, P: 1-12
Drug Insight: the use of melatonergic agonists for the treatment of insomnia—focus on ramelteon

Melatonin has been used successfully to treat insomnia, but has not received regulatory approval by the FDA because it can be sold freely as a food supplement. This has prompted a search by pharmaceutical companies for patentable melatonin receptor ligands, and the melatonin receptor agonist ramelteon has received particular attention. This Review describes the pharmacology and metabolism of ramelteon, assesses evidence from animal models and clinical studies that supports its efficacy in treating insomnia, and discusses its possible mechanism of action.

Seithikurippu R Pandi-Perumal
Venkataramanujan Srinivasan
Daniel P Cardinali
Reviews01 Apr 2007
Nature Clinical Practice Neurology

Volume: 3, P: 221-228
Outcomes and prognostic factors in patients with Burkitt lymphoma/leukemia in adolescents and adults: an experience from hematology cancer consortium

Akhil Rajendra
Manju Sengar
Aby Abraham
ResearchOpen Access15 Mar 2025
Blood Cancer Journal

Volume: 15, P: 1-12
Multidrug-resistant tuberculosis

Multidrug-resistant tuberculosis (MDR-TB) is caused by Mycobacterium tuberculosis that is resistant to several first-line drugs. MDR-TB is an increasing public health challenge. In this Primer, Dheda et al. summarize the epidemiology and mechanisms, and discuss diagnosis, management and quality of life of patients with MDR-TB.

Keertan Dheda
Fuad Mirzayev
Christoph Lange
Reviews24 Mar 2024
Nature Reviews Disease Primers

Volume: 10, P: 1-27
Cryptic binding sites become accessible through surface reconstruction of the type I collagen fibril

Jie Zhu
Cody L. Hoop
Jean Baum
ResearchOpen Access09 Nov 2018
Scientific Reports

Volume: 8, P: 1-12
Laser-scribed graphene nanofiber decorated with oil palm lignin capped silver nanoparticles: a green biosensor

Melvin Jia Yong Tai
Veeradasan Perumal
Wei-Wen Liu
ResearchOpen Access09 Mar 2021
Scientific Reports

Volume: 11, P: 1-9
A novel piperazine derivative that targets hepatitis B surface antigen effectively inhibits tenofovir resistant hepatitis B virus

S. Kiruthika
Ruchika Bhat
B. Jayaram
ResearchOpen Access03 Jun 2021
Scientific Reports

Volume: 11, P: 1-13
1,1'-Carbonyldiimidazole-copper nanoflower enhanced collapsible laser scribed graphene engraved microgap capacitive aptasensor for the detection of milk allergen

Indra Gandi Subramani
Veeradasan Perumal
Lim Li Sze
ResearchOpen Access21 Oct 2021
Scientific Reports

Volume: 11, P: 1-12
C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress

Adult neurons from Caenorhabditis elegans can extrude large membrane-surrounded vesicles, known as exophers, containing protein aggregates and dysfunctional organelles that threaten neuronal homeostasis.

Ilija Melentijevic
Marton L. Toth
Monica Driscoll
Research08 Feb 2017
Nature

Volume: 542, P: 367-371
Current practice of trabeculectomy in a cohort of experienced glaucoma surgeons in Australia and New Zealand

Graham A. Lee
Lance Liu
Sophia Zagora
ResearchOpen Access03 May 2022
Eye

Volume: 37, P: 1139-1144
LymphTF-DB: a database of transcription factors involved in lymphocyte development

P J Childress
R L Fletcher
N B Perumal
Research15 Mar 2007
Genes & Immunity

Volume: 8, P: 360-365
Clustering-based spatial analysis (CluSA) framework through graph neural network for chronic kidney disease prediction using histopathology images

Joonsang Lee
Elisa Warner
Arvind Rao
ResearchOpen Access05 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis

Rakesh Bhatia
Jawed Akhtar Siddiqui
Sushil Kumar
Research09 Jan 2023
Oncogene

Volume: 42, P: 759-770
Publisher Correction: Computer-aided interpretation of chest radiography reveals the spectrum of tuberculosis in rural South Africa

Jana Fehr
Stefan Konigorski
Zizile Sikhosana
Amendments and CorrectionsOpen Access16 Jul 2021
npj Digital Medicine

Volume: 4, P: 1
Correlating Photoluminescence and Structural Properties of Uncapped and GaAs-Capped Epitaxial InGaAs Quantum Dots

Arka B. Dey
Milan K. Sanyal
Vinayak Dravid
ResearchOpen Access14 May 2018
Scientific Reports

Volume: 8, P: 1-10
Unsupervised machine learning for identifying important visual features through bag-of-words using histopathology data from chronic kidney disease

Joonsang Lee
Elisa Warner
Arvind Rao
ResearchOpen Access22 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Laura M. Huckins
Amanda Dobbyn
Eli A. Stahl
Amendments and Corrections13 May 2019
Nature Genetics

Volume: 51, P: 1068
The safety and efficacy of BCG encapsulated alginate particle (BEAP) against M.tb H37Rv infection in Macaca mulatta : A pilot study

Ashwani Kesarwani
Parul Sahu
Pramod Upadhyay
ResearchOpen Access04 Feb 2021
Scientific Reports

Volume: 11, P: 1-10
Computer-aided interpretation of chest radiography reveals the spectrum of tuberculosis in rural South Africa

Jana Fehr
Stefan Konigorski
Zizile Sikhosana
ResearchOpen Access02 Jul 2021
npj Digital Medicine

Volume: 4, P: 1-10
MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis

E Maquoi
D Assent
A Noël
Research27 Jun 2011
Oncogene

Volume: 31, P: 480-493
Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM Challenge

Solveig K. Sieberts
Jennifer Schaff
Larsson Omberg
ResearchOpen Access19 Mar 2021
npj Digital Medicine

Volume: 4, P: 1-12
Evaluation of FLT-PET-CT as an imaging biomarker of proliferation in primary breast cancer

D K Woolf
M Beresford
A Makris
ResearchOpen Access15 May 2014
British Journal of Cancer

Volume: 110, P: 2847-2854

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