Nature Search

Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer

KRAS^G12D mutations frequently co-occur with mutated TP53 tumour suppressor in patients with pancreatic ductal adenocarcinoma (PDAC). Here the authors report the design of dual targeted therapeutic extracellular vesicles containing high copy numbers of TP53 mRNA and siKRAS^G12D, showing anti-tumor activity in PDAC preclinical models.

Chi-Ling Chiang
Yifan Ma
L. James Lee
ResearchOpen Access23 Oct 2023
Nature Communications

Volume: 14, P: 1-18
Infra-Red Absorption Bands of the Peptide Group

C. G. CANNON
B. C. STACE
R. JEFFRIES
Research03 Nov 1962
Nature

Volume: 196, P: 436-438
A taxonomic, genetic and ecological data resource for the vascular plants of Britain and Ireland

Marie C. Henniges
Robyn F. Powell
Ilia J. Leitch
ResearchOpen Access10 Jan 2022
Scientific Data

Volume: 9, P: 1-8
Double Helix at Atomic Resolution

JOHN M. ROSENBERG
NADRIAN C. SEEMAN
ALEXANDER RICH
Research18 May 1973
Nature

Volume: 243, P: 150-154
Binding of Hæmatin by Human Serum Albumin

H. N. LITTLE
J. B. NEILANDS
Research10 Dec 1960
Nature

Volume: 188, P: 913-915
Adaptive divergence and speciation among sexual and pseudoviviparous populations of Festuca

T Chiurugwi
M A Beaumont
N H Battey
Research20 Oct 2010
Heredity

Volume: 106, P: 854-861
Revealing the artist's touch

A. W. Snyder
H. B. Barlow
News & Views01 Jan 1988
Nature

Volume: 331, P: 117-118
NK2R control of energy expenditure and feeding to treat metabolic diseases

In mouse and nonhuman primate models, treatment with selective, long-acting neurokinin 2 receptor agonists aids weight loss by suppressing appetite and increasing energy expenditure, as well as by increasing insulin sensitivity.

Frederike Sass
Tao Ma
Zachary Gerhart-Hines
ResearchOpen Access13 Nov 2024
Nature

Volume: 635, P: 987-1000
Anatomical Information

B. M. G. JONES
Books & Arts14 May 1971
Nature

Volume: 231, P: 132
Pancreatobiliary diversion enhances experimental pancreatic carcinogenesis

ID Stewart
B Flaks
RCN Williamson
Research01 Jan 1991
British Journal of Cancer

Volume: 63, P: 63-66
Order in mammals

Malcolm C. McKenna
Books & Arts13 Dec 1984
Nature

Volume: 312, P: 675
Cancer metastasis is selective or random depending on the parent tumour population

J. E. Talmadge
I. J. Fidler
Research17 Jun 1982
Nature

Volume: 297, P: 593-594
Chemical Phenotypes of Pteridine Colour Forms in Pieris Butterflies

WARD B. WATT
S. R. BOWDEN
Research01 Apr 1966
Nature

Volume: 210, P: 304-306
The role of clonal selection and somatic mutation in autoimmunity

Mark J. Shlomchik
Ann Marshak-Rothstein
Martin G. Weigert
Research27 Aug 1987
Nature

Volume: 328, P: 805-811
Superabsorption of light via quantum engineering

A quantum system that super-radiates must also exhibit enhanced absorption, but the former always dominates in natural systems. However, by invoking environmental quantum control techniques, Higgins et al.demonstrate that a system can exhibit quantum-enhanced light absorption.

K. D. B. Higgins
S. C. Benjamin
E. M. Gauger
ResearchOpen Access22 Aug 2014
Nature Communications

Volume: 5, P: 1-7
EFFECTS OF LONG-TERM TRH ADMINISTRATION IN PATIENTS WITH IDIOPATHIC HYPOTALAÎ HYPOTHYROIDISM (IHH)

G F Rondanini
G de Panizza
G Chiumello
Research01 Jan 1988
Pediatric Research

Volume: 23, P: 134
Efficient non-Markovian quantum dynamics using time-evolving matrix product operators

In general the computational requirements for simulating quantum systems scale exponentially but in some cases it is possible to formulate more efficient schemes. Here the authors present an efficient approach to calculate non-Markovian quantum dynamics using matrix product operator methods.

A. Strathearn
P. Kirton
B. W. Lovett
ResearchOpen Access20 Aug 2018
Nature Communications

Volume: 9, P: 1-9
High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control

Factors underlying the effects of gastric bypass surgery on glucose homeostasis are incompletely understood. Here the authors developed and applied high-throughput mediation analysis to identify proteome/metabolome mediators of improved glucose homeostasis after to gastric bypass surgery, and report that improved glycemia was mediated by the growth hormone receptor.

Jonathan M. Dreyfuss
Yixing Yuchi
Mary Elizabeth Patti
ResearchOpen Access29 Nov 2021
Nature Communications

Volume: 12, P: 1-13
Inhibitory effect of a cholecystokinin antagonist on pancreatic carcinogenesis after pancreatobiliary diversion

P Watanapa
B Flaks
RCN Williamson
Research01 Apr 1993
British Journal of Cancer

Volume: 67, P: 663-667
A unified explanation of the Kadowaki–Woods ratio in strongly correlated metals

The Kadowaki–Woods ratio attempts to relate the temperature dependence of a metal to its heat capacity. However, as it takes different values for different classes of metals it is not universal. By including effects related to carrier density and spatial dimensionality, a much more universal ratio, which describes the properties of many different systems, has been achieved.

A. C. Jacko
J. O. Fjærestad
B. J. Powell
Research19 Apr 2009
Nature Physics

Volume: 5, P: 422-425
Isoenzymes as an aid to clarify the taxonomy of French elms

N Machon
M Lefranc
J-P Henry
Research01 Jan 1995
Heredity

Volume: 74, P: 39-47
The in vivo malignant transformation of mouse fibroblasts in the presence of human tumour xenografts

S Sparrow
M Jones
B Stace
Research01 Jun 1986
British Journal of Cancer

Volume: 53, P: 793-797

Search

Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer

Infra-Red Absorption Bands of the Peptide Group

A taxonomic, genetic and ecological data resource for the vascular plants of Britain and Ireland

Double Helix at Atomic Resolution

Binding of Hæmatin by Human Serum Albumin

Adaptive divergence and speciation among sexual and pseudoviviparous populations of Festuca

Revealing the artist's touch

NK2R control of energy expenditure and feeding to treat metabolic diseases

Anatomical Information

Pancreatobiliary diversion enhances experimental pancreatic carcinogenesis

Order in mammals

Cancer metastasis is selective or random depending on the parent tumour population

Chemical Phenotypes of Pteridine Colour Forms in Pieris Butterflies

The role of clonal selection and somatic mutation in autoimmunity

Superabsorption of light via quantum engineering

EFFECTS OF LONG-TERM TRH ADMINISTRATION IN PATIENTS WITH IDIOPATHIC HYPOTALAÎ HYPOTHYROIDISM (IHH)

Efficient non-Markovian quantum dynamics using time-evolving matrix product operators

High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control

Inhibitory effect of a cholecystokinin antagonist on pancreatic carcinogenesis after pancreatobiliary diversion

A unified explanation of the Kadowaki–Woods ratio in strongly correlated metals

Isoenzymes as an aid to clarify the taxonomy of French elms

The in vivo malignant transformation of mouse fibroblasts in the presence of human tumour xenografts

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