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Showing 1–50 of 1219 results

Advanced filters: Author: B. W. MATTHEWS Clear advanced filters

Natural Occurrence of Thymine and Three Methylated Adenine Bases in Several Ribonucleic Acids

J. W. LITTLEFIELD
D. B. DUNN
Research25 Jan 1958
Nature

Volume: 181, P: 254-255
Synthetic chaperone based on Hsp90-Tau interaction inhibits Tau aggregation and rescues physiological Tau-Microtubule interaction

Tau aggregation, a hallmark of Alzheimer’s disease, disrupts neuron structure. Aging weakens chaperone defenses like Hsp90. This study designs β-Hsp90, a small peptide mimicking Hsp90, to prevent Tau aggregation, offering promise for new amyloid disease drugs.

Davide Di Lorenzo
Nicolo Bisi
Sandrine Ongeri
ResearchOpen Access01 Oct 2025
Nature Communications

Volume: 16, P: 1-18
Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b

Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) is important for invasion of reticulocytes and PvRBP2b antibodies correlate with protection. Here, Chan et al. isolate and characterize anti-PvRBP2b human monoclonal antibodies and describe mechanisms by which these antibodies inhibit invasion.

Li-Jin Chan
Anugraha Gandhirajan
Wai-Hong Tham
ResearchOpen Access09 Mar 2021
Nature Communications

Volume: 12, P: 1-14
Chlorophyll arrangement in a bacteriochlorophyll protein from Chlorobium limicola

R. E. Fenna
B. W. Matthews
Research01 Dec 1975
Nature

Volume: 258, P: 573-577
Identification of two related pentapeptides from the brain with potent opiate agonist activity

J. Hughes
T. W. Smith
H. R. Morris
Research01 Dec 1975
Nature

Volume: 258, P: 577-579
The three-dimensional structure of trp repressor

Richard W. Schevitz
Zdzislaw Otwinowski
Paul B. Sigler
Research01 Oct 1985
Nature

Volume: 317, P: 782-786
Goose lysozyme structure: an evolutionary link between hen and bacteriophage lysozymes?

M. G. Grütter
L. H. Weaver
B. W. Matthews
Research30 Jun 1983
Nature

Volume: 303, P: 828-831
Pancake detonation of stars by black holes in galactic nuclei

B. Carter
J. P. Luminet
Research18 Mar 1982
Nature

Volume: 296, P: 211-214
Structure of the cro repressor from bacteriophage λ and its interaction with DNA

W. F. Anderson
D. H. Ohlendorf
B. W. Matthews
Research30 Apr 1981
Nature

Volume: 290, P: 754-758
Absolute Energy Distribution in the Optical Spectrum of 3C 273

J. B. OKE
Research16 Mar 1963
Nature

Volume: 197, P: 1040-1041
The molecular basis of DNA–protein recognition inferred from the structure of cro repressor

D. H. Ohlendorf
W. F. Anderson
B. W. Matthews
Research19 Aug 1982
Nature

Volume: 298, P: 718-723
Stimulation of Turnip Yellow Mosaic Virus Protein Production by 2-Thiouracil

R. I. B. FRANCKI
R. E. F. MATTHEWS
Research09 Sept 1961
Nature

Volume: 191, P: 1078-1080
Opening of the Atlantic Ocean

B. M. FUNNELL
A. GILBERT SMITH
Research28 Sept 1968
Nature

Volume: 219, P: 1328-1333
Measuring the semantic priming effect across many languages

In this Stage 2 Registered Report, Buchanan et al. show evidence confirming the phenomenon of semantic priming across speakers of 19 diverse languages.

Erin M. Buchanan
Kelly Cuccolo
Savannah C. Lewis
Research24 Sept 2025
Nature Human Behaviour

P: 1-20
Enhanced protein thermostability from designed mutations that interact with α-helix dipoles

H. Nicholson
W. J. Becktel
B. W. Matthews
Research15 Dec 1988
Nature

Volume: 336, P: 651-656
Human Calcitonin

R. NEHER
B. RINIKER
I. MacINTYRE
Research07 Dec 1968
Nature

Volume: 220, P: 984-986
Molecular basis of thermostability in the lysozyme from bacteriophage T4

MARKUS G. GRÜTTER
RICHARD B. HAWKES
BRIAN W. MATTHEWS
Research01 Feb 1979
Nature

Volume: 277, P: 667-669
Palmer Ridge: a Section through the Upper Part of the Ocean Crust?

J. R. CANN
B. M. FUNNELL
Research18 Feb 1967
Nature

Volume: 213, P: 661-664
The inner radio jet of 3C273

J. A. Zensus
L. B. Bååth
G. D. Nicolson
Research01 Aug 1988
Nature

Volume: 334, P: 410-412
Comparison of machine learning models for mucopolysaccharidosis early diagnosis using UAE medical records

Aamna AlShehhi
Hiba Alblooshi
Fatma Al-Jasmi
ResearchOpen Access06 Aug 2025
Scientific Reports

Volume: 15, P: 1-21
Major sea level fall during the Pliocene M2 glaciation

This study refines benthic foraminiferal Mg/Ca paleothermometry to reduce uncertainties to ±0.2-0.3 °C, which was then applied in Atlantic and Pacific sediment cores to reconstruct Mid-Pliocene M2 glaciation sea-level changes.

Zifei Yang
Caroline H. Lear
Amy Thomas-Sparkes
ResearchOpen Access16 Aug 2025
Nature Communications

Volume: 16, P: 1-12
Structure of the catalytic domain of human fibroblast collagenase complexed with an inhibitor

N. Borkakoti
F.K. Winkler
E.J. Murray
Research01 Feb 1994
Nature Structural Biology

Volume: 1, P: 106-110
Compact radio source 1413 + 135 is a far-IR extragalactic object

C. A. Beichman
G. Neugebauer
P. M. Harvey
Research29 Oct 1981
Nature

Volume: 293, P: 711-713
Redox state of the deep upper mantle recorded by nickel-rich diamond inclusions

Reduced nickel-rich metal and oxidized nickel carbonate inclusions within diamonds provide evidence of metasomatic redox reactions and support the role of carbonatitic melts in oxidizing small volumes of the deep upper mantle and transition zone.

Yael Kempe
Sergei Remennik
Yaakov Weiss
Research22 Sept 2025
Nature Geoscience

P: 1-8
A large model for non-invasive and personalized management of breast cancer from multiparametric MRI

Artificial intelligence-based studies for breast cancer magnetic resonance imaging (MRI) predominantly rely on single sequences and have limited validation. Here, the authors develop a mixture-of-modality-experts model (MOME) that integrates multiparametric breast cancer MRI information within a unified structure, which shows reliable performance in a large cohort.

Luyang Luo
Mingxiang Wu
Hao Chen
ResearchOpen Access17 Apr 2025
Nature Communications

Volume: 16, P: 1-14
A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity

Melissa M. Fitzgerald
Rabi A. Musah
David B. Goodin
Research01 Jul 1996
Nature Structural Biology

Volume: 3, P: 626-631
Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

D. M. BLOW
J. J. BIRKTOFT
B. S. HARTLEY
Research25 Jan 1969
Nature

Volume: 221, P: 337-340
Three-dimensional Structure of Tosyl-α-chymotrypsin

B. W. MATTHEWS
P. B. SIGLER
D. M. BLOW
Research13 May 1967
Nature

Volume: 214, P: 652-656
Common precursor of lysozymes of hen egg-white and bacteriophage T4

B. W. Matthews
M. G. Grütter
S. J. Remington
Research26 Mar 1981
Nature

Volume: 290, P: 334-335
Cell state-dependent allelic effects and contextual Mendelian randomization analysis for human brain phenotypes

Analysis of single nuclei RNA-sequencing data across eight major brain cell types identifies putative causal associations between cell-type-specific expression and brain phenotypes.

Alexander Haglund
Verena Zuber
Michael R. Johnson
ResearchOpen Access10 Jan 2025
Nature Genetics

Volume: 57, P: 358-368
The Cyclotron Unit: Medical Research Council

D. D. VONBERG
J. F. FOWLER
Research01 Jun 1963
Nature

Volume: 198, P: 827-832
A new DNA-binding motif in the Skn-1 binding domain–DNA complex

Peter B. Rupert
Gary W. Daughdrill
Brian W. Matthews
Research01 Jun 1998
Nature Structural Biology

Volume: 5, P: 484-491
Chemistry of the Oxidative Metabolism of Certain Aromatic Compounds by Micro-Organisms

W. CHARLES EVANS
B. S. W. SMITH
J. A. ELVIDGE
Research03 Nov 1951
Nature

Volume: 168, P: 772-775
AI-driven fusion of multimodal data for Alzheimer’s disease biomarker assessment

A flexible AI framework integrates multimodal neurology work-up data to estimate amyloid and tau burden, supporting scalable biomarker stratification for Alzheimer’s disease research and trial screening.

Varuna H. Jasodanand
Sahana S. Kowshik
Vijaya B. Kolachalama
ResearchOpen Access11 Aug 2025
Nature Communications

Volume: 16, P: 1-19
A mutant T4 lysozyme displays five different crystal conformations

H. R. Faber
B. W. Matthews
Research15 Nov 1990
Nature

Volume: 348, P: 263-266
Pluto's structure and composition suggest origin in the solar, not a planetary, nebula

William B. McKinnon
Steve Mueller
Research15 Sept 1988
Nature

Volume: 335, P: 240-243
Chemical Protection against Alpha-Particle Irradiation

TIKVAH ALPER
D. K. BEWLEY
J. F. FOWLER
Research30 Jun 1962
Nature

Volume: 194, P: 1245-1247
Crystallographic Studies of a Human Immunoglobulin

W. D. TERRY
B. W. MATTHEWS
D. R. DAVIES
Research19 Oct 1968
Nature

Volume: 220, P: 239-241
DrFARM: identification of pleiotropic genetic variants in genome-wide association studies

Standard approaches for identifying pleiotropic genetic variants may lead to spurious results. Here the authors present a new statistical method and show that it uncovers five genes linked to metabolites in METSIM participants, which were previously undetected by existing methods.

Lap Sum Chan
Gen Li
Peter X. K. Song
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
IR observations of the double quasar 0957 + 561 A, B and the intervening galaxy

B. T. Soifer
G. Neugebauer
R. Capps
Research08 May 1980
Nature

Volume: 285, P: 91-93
Ocean Surveys: The Systematic Approach

G. PETER
H. B. STEWART jun.
Research05 Jun 1965
Nature

Volume: 206, P: 1017-1018
Additional Identifications of Radio Sources with Star-Like Objects

C. HAZARD
M. B. MACKEY
W. NICHOLSON
Research18 Apr 1964
Nature

Volume: 202, P: 227-228
DRB-induced premature termination of late adenovirus transcription

Nigel W. Fraser
Pravinkumar B. Sehgal
James E. Darnell
Research13 Apr 1978
Nature

Volume: 272, P: 590-593
Demonstration of Super-X divertor exhaust control for transient heat load management in compact fusion reactors

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

B. Kool
K. Verhaegh
V. Zamkovska
ResearchOpen Access05 Sept 2025
Nature Energy

Volume: 10, P: 1116-1131
Three-dimensional Structure of Thermolysin

B. W. MATTHEWS
J. N. JANSONIUS
D. DUPOURQUE
Research12 Jul 1972
Nature New Biology

Volume: 238, P: 37-41
Late Miocene palaeo-oceanography of the Atlantic: oxygen isotope data on planktonic and benthic Foraminifera

R. K. Matthews
W. B. Curry
R. Z. Poore
Research07 Feb 1980
Nature

Volume: 283, P: 555-557
Structure of Thermolysin

B. W. MATTHEWS
P. M. COLMAN
H. NEURATH
Research12 Jul 1972
Nature New Biology

Volume: 238, P: 41-43
Accurately predicting enzyme functions through geometric graph learning on ESMFold-predicted structures

The Enzyme Commission (EC) number is a commonly used method for defining enzyme function. Here, authors propose GraphEC, a geometric graph learning-based EC number predictor to identify unannotated enzyme functions, predict their active sites, and determine their optimal pH.

Yidong Song
Qianmu Yuan
Yuedong Yang
ResearchOpen Access18 Sept 2024
Nature Communications

Volume: 15, P: 1-11
Magnetism and Opaque Mineralogy of Basalts from the Mid-Atlantic Ridge at 45° N

E. IRVING
J. K. PARK
B. LONCAREVIC
Research05 Dec 1970
Nature

Volume: 228, P: 974-976
A low-temperature companion to a white dwarf star

E. E. Becklin
B. Zuckerman
Research15 Dec 1988
Nature

Volume: 336, P: 656-658

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