Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–13 of 13 results
Advanced filters: Author: Bradley C. Lega Clear advanced filters

  • Memory loss is a known result of cholinergic dysfunction, yet the neural basis for this effect remains unknown. Here, the authors demonstrate that the way cholinergic blockade disrupts memory is by impairing the amplitude and timing of theta oscillations.

    • Tamara Gedankien
    • Ryan Joseph Tan
    • Bradley Lega
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Cryo-electron microscopy structures of native type A GABA receptors from human brain reveal diverse subunit compositions, protein binding partners and binding sites for antiepileptic drugs.

    • Jia Zhou
    • Colleen M. Noviello
    • Ryan E. Hibbs
    Research
    Nature
    Volume: 638, P: 562-568

  • How can the brain improve memory for an experience after it has occurred? Halpern et al. use intracranial EEG to show that, even while processing current experiences, people reactivate old ones and re-encode them, turning thoughts into memories.

    • David J. Halpern
    • Bradley C. Lega
    • Michael J. Kahana
    Research
    Nature Neuroscience
    Volume: 28, P: 883-890

  • Neuronal assemblies remain understudied in human data. Here, the authors show that gamma phase-locked neuronal firing sequences comprise assemblies in human single unit recordings, and their ability to incorporate new neurons over time facilitates memory.

    • Gray Umbach
    • Ryan Tan
    • Bradley Lega
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • People can search for memories based on their content or context, defined as when and where they were formed. Here, the authors use direct brain recordings to provide evidence in line with the idea that separable neural systems retrieve these two types of information and predict whether recall is organized by time or content.

    • James E. Kragel
    • Youssef Ezzyat
    • Michael J. Kahana
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • We show that the human hippocampus exhibits two distinct theta oscillations during spatial navigation with the faster oscillation in posterior regions showing movement modulation. This result suggests a distinct feature of the human hippocampus compared to rodents, which generally show a single 8 Hz rhythm.

    • Abhinav Goyal
    • Jonathan Miller
    • Joshua Jacobs
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • Memory lapses can occur due to ineffective encoding, but it is unclear if targeted brain stimulation can improve memory performance. Here, authors use a closed-loop system to decode and stimulate periods of ineffective encoding, showing that stimulation of lateral temporal cortex can enhance memory.

    • Youssef Ezzyat
    • Paul A. Wanda
    • Michael J. Kahana
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-8

  • Theta oscillations are implicated in memory formation. Here, the authors show that low-theta oscillations in the hippocampus are differentially modulated between each hemisphere, with oscillations in the left increasing when successfully learning object–location pairs and in the right during spatial navigation.

    • Jonathan Miller
    • Andrew J. Watrous
    • Joshua Jacobs
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12