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Showing 1–12 of 12 results

Advanced filters: Author: C Arruabarrena Clear advanced filters

Diagnostics of diabetic retinopathy based on fundus photos using machine learning methods with advanced feature engineering algorithms

Michał Gandor
Filip Pałka
Marek Sylwestrzak
ResearchOpen Access03 Oct 2025
Scientific Reports

Volume: 15, P: 1-16
The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

Torrano et al. use bioinformatics analyses to identify PGC1α as a transcriptional regulator of a metabolic program downstream of ERRα that opposes metastatic dissemination in prostate cancer.

Veronica Torrano
Lorea Valcarcel-Jimenez
Arkaitz Carracedo
Research23 May 2016
Nature Cell Biology

Volume: 18, P: 645-656
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis

During the formation of vascular sprouts, Notch activation inhibits proliferation of the stalk ECs via unknown mechanism. Here the authors show that PTEN represents a critical mediator of Notch anti-proliferative response in stalk cells via its phosphatase-dependent and -independent activity.

Helena Serra
Iñigo Chivite
Mariona Graupera
ResearchOpen Access31 Jul 2015
Nature Communications

Volume: 6, P: 1-13
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

mTOR complex 1 signalling regulates polyamine metabolism and thereby promotes tumorigenesis, through regulation of the stability of a key enzyme, AMD1.

Amaia Zabala-Letona
Amaia Arruabarrena-Aristorena
Arkaitz Carracedo
Research28 Jun 2017
Nature

Volume: 547, P: 109-113
Brolucizumab clinical and safety outcomes in a neovascular age-related macular degeneration national database: Fight Retinal Blindness Spain (FRB Spain)

Javier Zarranz-Ventura
Sonia Marías-Pérez
Lucia Miguel-Escuder
Research05 Jun 2025
Eye

Volume: 39, P: 2407-2414
Fight Retinal Blindness SPAIN. Report 3: clinical outcomes of vascular endothelial growth factor inhibitors in low vision eyes with neovascular age-related macular degeneration. A national database study

Martín Puzo
Pilar Calvo-Perez
Javier Zarranz-Ventura
Research21 Sept 2024
Eye

Volume: 38, P: 3450-3458
Initial response and 12-month outcomes after commencing dexamethasone or vascular endothelial growth factor inhibitors for retinal vein occlusion in the FRB registry

Gonzaga Garay-Aramburu
Adrian Hunt
Javier Zarranz-Ventura
ResearchOpen Access13 Mar 2024
Scientific Reports

Volume: 14, P: 1-11
PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer

Amaia Zabala-Letona
Amaia Arruabarrena-Aristorena
Arkaitz Carracedo
ResearchOpen Access23 Feb 2022
Oncogenesis

Volume: 11, P: 1-9
Ocular residual astigmatism’s effect on high myopic astigmatism LASIK surgery

M A Teus
C Arruabarrena
D G Mikropoulos
Research27 Jun 2014
Eye

Volume: 28, P: 1014-1019
Cancer metabolism: fatty acid oxidation in the limelight

The vast majority of the research into cancer metabolism has been limited to a handful of metabolic pathways, with other pathways being sidelined. This Progress article brings to light the potential contribution of fatty acid oxidation to cancer cell function.

Arkaitz Carracedo
Lewis C. Cantley
Pier Paolo Pandolfi
Reviews28 Feb 2013
Nature Reviews Cancer

Volume: 13, P: 227-232
Longer treatment intervals are associated with reduced treatment persistence in neovascular age related macular degeneration

Kelvin Y. C. Teo
Vuong Nguyen
Mark C. Gillies
Research09 Feb 2022
Eye

Volume: 37, P: 467-473
Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells

I Hermanova
A Arruabarrena-Aristorena
J Starkova
Research04 Aug 2015
Leukemia

Volume: 30, P: 209-218