Nature Search

Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial

While fluid restriction is typically recommended for patients with chronic heart failure, this randomized clinical trial showed no difference in health status, as assessed by patient-reported outcomes, between patients recommended to a liberal versus a restrictive fluid regimen over the course of 3 months in an outpatient setting.

Job J. Herrmann
Hans-Peter Brunner-La Rocca
Roland R. J. van Kimmenade
Research30 Mar 2025
Nature Medicine

Volume: 31, P: 2062-2068
Evidence for Asymmetry of Jupiter's Van Allen Belt

J. A. ROBERTS
M. M. KOMESAROFF
Research22 Aug 1964
Nature

Volume: 203, P: 827-830
Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance atherosclerotic plaque formation through delivery of miR-155.

Ingrid Gomez
Ben Ward
Victoria Ridger
ResearchOpen Access10 Jan 2020
Nature Communications

Volume: 11, P: 1-18
Defective polymorphonuclear leukocyte function in a human periodontal disease

L. J. CIANCIOLA
R. J. GENCO
C. J. VAN OSS
Research01 Feb 1977
Nature

Volume: 265, P: 445-447
A smart framework to design membranes for organic micropollutants removal

It is crucial, yet challenging, to develop effective polymeric membranes for removing organic micropollutants from water. Here the authors present a data-mechanism-fused machine learning approach to assist the development of such membranes.

Dan Lu
Zihang Zhao
Lin Zhang
Research25 Aug 2025
Nature Sustainability

P: 1-13
Revealing the spatio-phenotypic patterning of cells in healthy and tumor tissues with mLSR-3D and STAPL-3D

An imaging software for large-scale microscopy data shows how cells are organized in tissues.

Ravian L. van Ineveld
Michiel Kleinnijenhuis
Anne C. Rios
Research03 Jun 2021
Nature Biotechnology

Volume: 39, P: 1239-1245
Increased Permeability to Albumin induced with Protamine in Modified Gelatine Membranes

BØRGE LARSEN
Research05 Aug 1967
Nature

Volume: 215, P: 641-642
A-nor-steranes, a novel class of sedimentary hydrocarbons

Ger van Graas
F. de Lange
P. A. Schenck
Research04 Mar 1982
Nature

Volume: 296, P: 59-61
Surface and cell membrane activities of leukocyte chemotactic factors

P. C. WILKINSON
Research06 Sept 1974
Nature

Volume: 251, P: 58-60
Reiteration frequency of the gene for tissue-specific histone H5 in the chicken genome

A. C. Scott
J. R. E. Wells
Research26 Feb 1976
Nature

Volume: 259, P: 635-638
Chiral selection in poly(C)-directed synthesis of oligo(G)

G. F. Joyce
G. M. Visser
J. van Westrenen
Research16 Aug 1984
Nature

Volume: 310, P: 602-604
Offshore wind energy: assessing trace element inputs and the risks for co-location of aquaculture

G. J. Watson
G. Banfield
A. Hodkin
ResearchOpen Access19 Jan 2025
npj Ocean Sustainability

Volume: 4, P: 1-10
Oxidative stress status in patients with diabetes mellitus: relationship to diet

N Dierckx
G Horvath
B Manuel-y-Keenoy
Research24 Jul 2003
European Journal of Clinical Nutrition

Volume: 57, P: 999-1008
Extreme river flood exposes latent erosion risk

Analysis of the 2021 Meuse River flood reveals potential erosion risks due to uneven river widening and subsoil variability, highlighting challenges for river engineering and flood mitigation in a changing climate.

H. J. Barneveld
R. M. Frings
A. J. F. Hoitink
ResearchOpen Access10 Jul 2025
Nature

Volume: 644, P: 391-397
Mitotic errors in somatic cells cause trisomy 21 in about 4.5% of cases and are not associated with advanced maternal age

Stylianos E. Antonarakis
Dimitrios Avramopoulos
Albert A. Schinzel
Research01 Feb 1993
Nature Genetics

Volume: 3, P: 146-150
Anticomplementary Action of Aspirin

C. J. VAN OSS
J. C. FRIEDMANN
M. FONTAINE
Research14 Jan 1961
Nature

Volume: 189, P: 147
The hepatitis delta (δ) virus possesses a circular RNA

A. Kos
R. Dijkema
H. Schellekens
Research09 Oct 1986
Nature

Volume: 323, P: 558-560
Symbiosis of methylotrophic bacteria and deep-sea mussels

Colleen M. Cavanaugh
Piet R. Levering
Mary E. Lidstrom
Research22 Jan 1987
Nature

Volume: 325, P: 346-348
Expression of active human factor VIII from recombinant DNA clones

William I. Wood
Daniel J. Capon
Richard M. Lawn
Research22 Nov 1984
Nature

Volume: 312, P: 330-337
Cosmic dust collection by the capture cell technique on the Space Shuttle

J. A. M. McDonnell
W. C. Carey
D. G. Dixon
Research17 May 1984
Nature

Volume: 309, P: 237-240
Conformational Analysis of N⁶-Methyladenylyl-Uridine

C. ALTONA
J. H. VAN BOOM
G. VAN BINST
Research22 Feb 1974
Nature

Volume: 247, P: 558-561
Influence of Anabolic Steroids versus Effect of Glucose on Muscular Degeneration in Pigs

P. C. HART
D. KROESKE
H. E. V. D. VEEN
Research18 May 1963
Nature

Volume: 198, P: 716
Structure-based design and protein engineering of intersubunit disulfide bonds in gonadotropins

Judith C. Heikoop
Paul van den Boogaart
Peter D.J. Grootenhuis
Research01 Jul 1997
Nature Biotechnology

Volume: 15, P: 658-662
The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor

C. Calleja
J.M. Pascussi
M.J. Vilarem
Research01 Jan 1998
Nature Medicine

Volume: 4, P: 92-96
Hepatitis B polypeptide vaccine preparation in micelle form

Jacinta Skelly
C. R. Howard
A. J. Zuckerman
Research01 Mar 1981
Nature

Volume: 290, P: 51-54
Neuraminidase in Avian Influenza A Virus antigenically related to that of Human A0 and A1 Subtypes

G. C. SCHILD
H. G. PEREIRA
C. H. SCHETTLER
Research28 Jun 1969
Nature

Volume: 222, P: 1299-1301
Modulation of Protein Fouling and Interfacial Properties at Carbon Surfaces via Immobilization of Glycans Using Aryldiazonium Chemistry

Federico Zen
M. Daniela Angione
Paula E. Colavita
ResearchOpen Access25 Apr 2016
Scientific Reports

Volume: 6, P: 1-10
Adsorption on Carbon of Rare Earth Organic Complexes

R. C. VICKERY
Research02 Nov 1946
Nature

Volume: 158, P: 623-624
Hierarchical mechanism of amino acid sensing by the T-box riboswitch

Riboswitches on 5′ ends of mRNAs are important for bacterial gene regulation. Here the authors probe the mechanism of a tRNA aminoacylation sensing T-box riboswitch using single-molecule fluorescence microscopy to characterize dynamic solution conformations and heterogeneous tRNA binding kinetics.

Krishna C. Suddala
Javier Cabello-Villegas
Nils G. Walter
ResearchOpen Access14 May 2018
Nature Communications

Volume: 9, P: 1-14
Genetic Control of Lipid Metabolism in Tribolium

ROBERT F. COSTANTINO
A. E. BELL
JOHN C. ROGLER
Research09 Apr 1966
Nature

Volume: 210, P: 221-222
Some Bands of the Carbon Molecule

R. C. JOHNSON
Research18 Jan 1930
Nature

Volume: 125, P: 89-90
A mechanism for heparin-induced potentiation of antithrombin III

C.A.A. van Boeckel
P.D.J. Grootenhuis
A. Visser
Correspondence01 Jul 1994
Nature Structural Biology

Volume: 1, P: 423-425
Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans

Here, Brotherton and colleagues sequence 39 mitochondrial genomes from ancient human remains. They track population changes across Central Europe and find that the foundations of the European mitochondrial DNA pool were formed during the Neolithic rather than the post-glacial period.

Paul Brotherton
Wolfgang Haak
Janet S. Ziegle
Research23 Apr 2013
Nature Communications

Volume: 4, P: 1-11
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence

Chemotherapy-induced peripheral neuropathy (CIPN) represents a major reason for discontinuation of treatment. Here, the authors show that LEI-515, a peripherally restricted monoacylglycerol lipase inhibitor, suppresses CIPN without inducing central nervous system side effects or physical dependence.

Ming Jiang
Mirjam C. W. Huizenga
Mario van der Stelt
ResearchOpen Access05 Dec 2023
Nature Communications

Volume: 14, P: 1-19
Computer prehistory

C. J. VAN OSS
Correspondence20 Nov 1975
Nature

Volume: 258, P: 192
Chemical and structural heterogeneity of olive leaves and their trichomes

By combining different microscopy techniques, olive leaf surfaces are shown to be chemically heterogeneous due to the occurrence of trichomes which have mixed hydrophilic-hydrophobic areas at the nanoscale level.

Victoria Fernández
Lisa Almonte
Jaime Colchero
ResearchOpen Access22 Mar 2024
Communications Biology

Volume: 7, P: 1-12
Targeting N-myristoylation for therapy of B-cell lymphomas

N-myristoyltransferases (NMTs) target many signaling proteins to membranes. Here the authors show an NMT inhibitor named PCLX-001 selectively kills lymphoma cells by shutting down their main survival signaling pathway and offers an additional treatment strategy for lymphoma patients.

Erwan Beauchamp
Megan C. Yap
Luc G. Berthiaume
ResearchOpen Access22 Oct 2020
Nature Communications

Volume: 11, P: 1-16
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

An inhibitor of NAPE-PLD involved in lipid biosynthesis lowers levels of the endocannabinoid anandamide and other N-acylethanolamines in cells and mouse brain and activates the hypothalamus–pituitary–adrenal axis and impaired fear extinction.

Elliot D. Mock
Mohammed Mustafa
Mario van der Stelt
Research11 May 2020
Nature Chemical Biology

Volume: 16, P: 667-675
An extremely powerful long-lived superluminal ejection from the black hole MAXI J1820+070

Radio observations of black hole MAXI J1820+070’s 2018 outburst captured an isolated radio flare that the authors connect with the launch of bipolar relativistic ejecta. Following the oncoming ejecta for more than half a year reveals that black hole jet energetics have been systematically underestimated.

J. S. Bright
R. P. Fender
R. A. M. J. Wijers
Research02 Mar 2020
Nature Astronomy

Volume: 4, P: 697-703
Safety and efficacy of a non-steroidal anti-androgen, based on results of a post marketing surveillance of nilutamide

EMC Schasfoort
C van de Beek
DWW Newling
Research29 Jun 2001
Prostate Cancer and Prostatic Diseases

Volume: 4, P: 112-117
Optical and surface energy probe of Hamaker constant in copper oxide thin films for NEMS and MEMS stiction control applications

Abraham Ogwu
T. H. Darma
ResearchOpen Access19 Feb 2021
Scientific Reports

Volume: 11, P: 1-11
Family integrated care reduces stress in transferred parents of preterm infants, but not across all families: a stepped-wedge cluster-randomized trial

M. T. Alferink
H. Hoeben
F. Visser
Research20 May 2025
Journal of Perinatology

Volume: 45, P: 797-805
Identification of an allosteric binding site for RORγt inhibition

Upon the binding of small ligands, nuclear receptors regulate the transcription of genes that are associated with a number of disease mechanisms. Here, the authors report on a novel allosteric ligand binding site on the nuclear receptor RORγt.

Marcel Scheepstra
Seppe Leysen
Luc Brunsveld
ResearchOpen Access07 Dec 2015
Nature Communications

Volume: 6, P: 1-10
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

There is increasing evidence that protein-coding genes can emerge de novo from noncoding genomic regions. Vakirlis et al. propose that sequences encoding transmembrane polypeptides can emerge de novo in thymine-rich genomic regions and provide organisms with fitness benefits.

Nikolaos Vakirlis
Omer Acar
Anne-Ruxandra Carvunis
ResearchOpen Access07 Feb 2020
Nature Communications

Volume: 11, P: 1-18
Space Bioprocessing

Paul Todd
Research01 Sept 1985
Bio/Technology

Volume: 3, P: 786-790
Genomic monitoring to understand the emergence and spread of Usutu virus in the Netherlands, 2016–2018

B. Bas Oude Munnink
E. Münger
M. Koopmans
ResearchOpen Access18 Feb 2020
Scientific Reports

Volume: 10, P: 1-10
Global probabilistic projections of extreme sea levels show intensification of coastal flood hazard

Extreme sea levels are a flood risk along the world’s coastlines. Here the authors carry out probabilistic projections of extreme sea levels and show that for the present century coastal flood hazards will increase significantly along most of the global coastlines.

Michalis I. Vousdoukas
Lorenzo Mentaschi
Luc Feyen
ResearchOpen Access18 Jun 2018
Nature Communications

Volume: 9, P: 1-12
Long-term sea level rise modeling of a basin-tidal inlet system reveals sediment sinks

Barrier islands and backbarrier saltmarshes are particularly threatened by sea level rise. Here, the authors show how reduction in intertidal areas create negative feedback, shifting transport of coarse sediment through the inlet from net export to net import.

Kevin C. Hanegan
Duncan M. FitzGerald
Zoe J. Hughes
ResearchOpen Access06 Nov 2023
Nature Communications

Volume: 14, P: 1-13
Evaluation of the efficacy of cystinosin supplementation through CTNS mRNA delivery in experimental models for cystinosis

Tjessa Bondue
Sante Princiero Berlingerio
Elena Levtchenko
ResearchOpen Access28 Nov 2023
Scientific Reports

Volume: 13, P: 1-14
Machine learning-based somatic variant calling in cell-free DNA of metastatic breast cancer patients using large NGS panels

Elisabeth M. Jongbloed
Maurice P. H. M. Jansen
Stavros Makrodimitris
ResearchOpen Access27 Jun 2023
Scientific Reports

Volume: 13, P: 1-11

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