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Showing 1–19 of 19 results
Advanced filters: Author: Carole A. Ridge Clear advanced filters

  • Multibeam mapping of the northwestern Indian Ocean seafloor provides clear evidence of dextral strike-slip motion along the Owen fracture zone and helps constrain the nature of deformation as well as the rate of slip along this little-studied plate boundary.

    • Marc Fournier
    • Nicolas Chamot-Rooke
    • Claude Lepvrier
    Research
    Nature Geoscience
    Volume: 1, P: 54-58

  • Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

    • B. Kool
    • K. Verhaegh
    • V. Zamkovska
    ResearchOpen Access
    Nature Energy
    Volume: 10, P: 1116-1131

  • [NiFe] hydrogenases are enzymes containing nickel and iron centres that catalyse hydrogen evolution with performances that rival those of platinum catalysts. Now, a NiFe model complex has been reported that mimics the structure and the Ni-centred hydrogen evolution activity found at the active site of [NiFe] hydrogenases.

    • Deborah Brazzolotto
    • Marcello Gennari
    • Carole Duboc
    Research
    Nature Chemistry
    Volume: 8, P: 1054-1060

  • Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

    • Céline Bellenguez
    • Fahri Küçükali
    • Jean-Charles Lambert
    ResearchOpen Access
    Nature Genetics
    Volume: 54, P: 412-436

  • The ancestry of the European bison (wisent) remains a mystery. Here, Cooper and colleagues examine ancient DNA from fossil remains of extinct bison, and reveal the wisent originated through the hybridization of the extinct Steppe bison and ancestors of modern cattle.

    • Julien Soubrier
    • Graham Gower
    • Alan Cooper
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-7

  • Opaque tissues provide a challenge for live imaging of Xenopus laevis development; a problem solved by in vivo time-lapse X-ray microtomography that is shown to provide a high-resolution three-dimensional view of structural changes and dynamics of gastrulation, and that is applied to identify and analyse new aspects of gastrulation in frog embryos.

    • Julian Moosmann
    • Alexey Ershov
    • Ralf Hofmann
    Research
    Nature
    Volume: 497, P: 374-377

  • Chromodomain Helicase DNA-binding (CHD) proteins have been implicated in neurodevelopmental processes. Here, the authors identify missense variants in CHD3 that disturb its chromatin remodeling activities and cause a neurodevelopmental disorder with macrocephaly and speech and language impairment.

    • Lot Snijders Blok
    • Justine Rousseau
    • Philippe M. Campeau
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12

  • Two executives—one from a leading generics manufacturer, the other from a leading brand manufacturer—argue the pros and cons of implementing an abbreviated US regulatory framework for the approval of biogeneric products.

    • Carole S Ben-Maimon
    • Rob Garnick
    Comments & Opinion
    Nature Biotechnology
    Volume: 24, P: 268

  • Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

    • Heather J. Cordell
    • Younghun Han
    • Katherine A. Siminovitch
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-11

  • Power exhaust is one of the biggest challenges stopping fusion energy. This article shows experimental evidence for strategically shaping the power exhaust region as a solution to this challenge, utilising physics understanding to strike a balance between engineering complexity and power exhaust benefits, consistent with reduced models and simulations.

    • Kevin Verhaegh
    • James Harrison
    • V. Zamkovska
    ResearchOpen Access
    Communications Physics
    Volume: 8, P: 1-15

  • Recent trends within computational and data sciences show an increasing recognition and adoption of computational workflows as tools for productivity and reproducibility that also democratize access to platforms and processing know-how. As digital objects to be shared, discovered, and reused, computational workflows benefit from the FAIR principles, which stand for Findable, Accessible, Interoperable, and Reusable. The Workflows Community Initiative’s FAIR Workflows Working Group (WCI-FW), a global and open community of researchers and developers working with computational workflows across disciplines and domains, has systematically addressed the application of both FAIR data and software principles to computational workflows. We present recommendations with commentary that reflects our discussions and justifies our choices and adaptations. These are offered to workflow users and authors, workflow management system developers, and providers of workflow services as guidelines for adoption and fodder for discussion. The FAIR recommendations for workflows that we propose in this paper will maximize their value as research assets and facilitate their adoption by the wider community.

    • Sean R. Wilkinson
    • Meznah Aloqalaa
    • Carole Goble
    Comments & OpinionOpen Access
    Scientific Data
    Volume: 12, P: 1-9