Nature Search

The impact of obstructive sleep apnea and heart rate on arterial stiffness: results from the Tokyo Sleep Heart Study

Junya Kani
Kazuki Shiina
Kazuhiro Satomi
ResearchOpen Access22 Aug 2025
Hypertension Research

Volume: 48, P: 2792-2800
RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function

RPL3L is a paralog of the ribosomal protein RPL3 and specifically expressed in heart and skeletal muscle. Here, the authors show that RPL3L-containing ribosomes regulate translation elongation dynamics especially for the transcripts related to cardiac muscle contraction.

Chisa Shiraishi
Akinobu Matsumoto
Keiichi I. Nakayama
ResearchOpen Access20 Apr 2023
Nature Communications

Volume: 14, P: 1-17
Digital hypertension – what we need for the high-quality management of hypertension in the new era

This article summarizes the latest information and discussions about digital hypertension from the Digital Hypertension symposium that took place during the 2024 Japan Society of Hypertension scientific meeting.

Kazuomi Kario
Kei Asayama
Satoshi Hoshide
Reviews30 Sept 2025
Hypertension Research

P: 1-17
Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

Shiro Ikegawa and colleagues report a genome-wide association study for adolescent idiopathic scoliosis (AIS). They identify one locus associated with AIS on chromosome 6q24.1 in Japanese individuals, which was also replicated in individuals of Han Chinese and European ancestry.

Ikuyo Kou
Yohei Takahashi
Shiro Ikegawa
Research12 May 2013
Nature Genetics

Volume: 45, P: 676-679
Hypertensive disorders of pregnancy and the risk of dementia: a systematic review and meta-analysis of cohort studies

Ahmed Arafa
Rena Kashima
Yoshihiro Kokubo
Research01 Dec 2023
Hypertension Research

Volume: 47, P: 859-866
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis

A number of testes-specific lncRNAs have been annotated but their roles remain largely unexplored. Here the authors identify two small peptides encoded by the lncRNA Gm9999, Kastor and Polluks, both of which are required for male fertility in mice.

Shintaro Mise
Akinobu Matsumoto
Keiichi I. Nakayama
ResearchOpen Access28 Feb 2022
Nature Communications

Volume: 13, P: 1-17
Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling

Sclerosing bone disorder (SBD) includes a broad spectrum of monogenic diseases characterised by increased bone density. Here, the authors describe a previously unknown SBD in four families caused by mutations in TMEM53 and demonstrate the role this protein plays in BMP signalling during bone formation.

Long Guo
Aritoshi Iida
Shiro Ikegawa
ResearchOpen Access06 Apr 2021
Nature Communications

Volume: 12, P: 1-13
A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer

Glucose metabolism is known to be dysregulated in cancer. Here, the authors show that glutamine nitrogen is also affected in cancer and demonstrate that glutaminase 1 and phosphoribosyl pyrophosphate amidotransferase are the key enzymes that control this metabolic switch.

Manabu Kodama
Kiyotaka Oshikawa
Keiichi I. Nakayama
ResearchOpen Access17 Mar 2020
Nature Communications

Volume: 11, P: 1-16
Systolic blood pressure lower than 130 mmHg in heart failure with preserved ejection fraction: a systematic review and meta-analysis of clinical outcomes

Chisa Matsumoto
Michiaki Nagai
Hisatomi Arima
ResearchOpen Access23 May 2025
Hypertension Research

Volume: 48, P: 2138-2151
Are the cardiovascular outcomes of participants with white-coat hypertension poor compared to those of participants with normotension? A systemic review and meta-analysis

Takeshi Fujiwara
Chisa Matsumoto
Satoshi Hoshide
Research10 Apr 2019
Hypertension Research

Volume: 42, P: 825-833
How to manage water and salt intake during the hot summer of 2025

Takuya Kishi
Katsuyuki Miura
Kazuomi Kario
Editorial27 Aug 2025
Hypertension Research

Volume: 48, P: 2789-2791
The Relationships of Cardiovascular Disease Risk Factors to Flow-Mediated Dilatation in Japanese Subjects Free of Cardiovascular Disease

Hirofumi Tomiyama
Chisa Matsumoto
Akira Yamashina
Research01 Nov 2008
Hypertension Research

Volume: 31, P: 2019-2025
Overweight Body Mass Index Classification Modifies Arterial Stiffening Associated with Weight Gain in Healthy Middle-Aged Japanese Men

Jiko Yamada
Hirofumi Tomiyama
Akira Yamashina
Research01 Jun 2008
Hypertension Research

Volume: 31, P: 1087-1092
2023 update and perspectives

Masaki Mogi
Atsushi Tanaka
Kazuomi Kario
Reviews15 Sept 2023
Hypertension Research

Volume: 47, P: 6-32
The association between the estimated glomerular filtration rate and cognitive impairment: the Suita Study

Ahmed Arafa
Haruna Kawachi
Yoshihiro Kokubo
Research23 Oct 2023
Hypertension Research

Volume: 47, P: 672-676
Nutrition and Hypertension Researches in 2023: focus on salt intake and blood pressure

Chisa Matsumoto
ReviewsOpen Access27 Jan 2025
Hypertension Research

Volume: 48, P: 1471-1476
Concomitant existence and interaction of cardiovascular abnormalities in obstructive sleep apnea subjects with normal clinic blood pressure

Hirofumi Tomiyama
Yoshifumi Takata
Akira Yamashina
Research23 Jan 2009
Hypertension Research

Volume: 32, P: 201-206
Central blood pressure: a powerful predictor of the development of hypertension

Hirofumi Tomiyama
Michael F O'rourke
Akira Yamashina
Research09 Aug 2012
Hypertension Research

Volume: 36, P: 19-24
Significance of the second peak of systolic blood pressure for identifying both high and low cardiovascular risk states

Chisa Matsumoto
Hirofumi Tomiyama
Akira Yamashina
Research05 Feb 2010
Hypertension Research

Volume: 33, P: 360-366
Association of blood pressure levels with the effects of alcohol intake on the vasculature in Japanese men

Chisa Matsumoto
Hirofumi Tomiyama
Akira Yamashina
Research16 Jan 2009
Hypertension Research

Volume: 32, P: 127-132
The necessity of investigations to clarify sex and racial disparities in pathophysiology of Long COVID

Chisa Matsumoto
Comments & Opinion31 Jan 2024
Hypertension Research

Volume: 47, P: 984-986
An evidence review project for food with function claims ~Challenges of the Japan society for vascular failure for the promotion of adequate evidences for food with function claims

Chisa Matsumoto
Hirofumi Tomiyama
Koichi Node
Comments & Opinion31 Oct 2023
Hypertension Research

Volume: 47, P: 533-536
Reply to: Microvascular hypertensive disease, long COVID, and end-organ pathology

Chisa Matsumoto
Correspondence13 Jul 2023
Hypertension Research

Volume: 46, P: 2249-2250
The impacts of secondhand smoke on future generations and the responsibility of society as a whole to protect the well-being of our future descendants

Chisa Matsumoto
Comments & Opinion08 Feb 2023
Hypertension Research

Volume: 46, P: 887-889
Effectiveness of a computerized clinical decision support system for prevention of glucocorticoid-induced osteoporosis

Toru Morikawa
Mio Sakuma
Takeshi Morimoto
ResearchOpen Access02 Sept 2022
Scientific Reports

Volume: 12, P: 1-10
Differences in longitudinal associations of cardiovascular risk factors with arterial stiffness and pressure wave reflection in middle-aged Japanese men

Masatsune Fujii
Hirofumi Tomiyama
Taishiro Chikamori
Research28 Jul 2020
Hypertension Research

Volume: 44, P: 98-106
Long COVID and hypertension-related disorders: a report from the Japanese Society of Hypertension Project Team on COVID-19

Chisa Matsumoto
Shigeru Shibata
Hiromi Rakugi
Reviews27 Dec 2022
Hypertension Research

Volume: 46, P: 601-619
Modulation of blood pressure-lowering effects of dark chocolate according to an insulin sensitivity-randomized crossover study

Chisa Matsumoto
Hirofumi Tomiyama
Akira Yamshina
Correspondence20 Jan 2020
Hypertension Research

Volume: 43, P: 575-578
Gender difference in the effects of cacao polyphenols on blood pressure and glucose/lipid metabolism in prediabetic subjects: a double-blinded, randomized, placebo-controlled crossover trial

Kazuki Shiina
Hirofumi Tomiyama
Akira Yamashina
Correspondence17 Jan 2019
Hypertension Research

Volume: 42, P: 1083-1085
COVID-19 pandemic and hypertension: an updated report from the Japanese Society of Hypertension project team on COVID-19

Shigeru Shibata
Kazuo Kobayashi
Hiromi Rakugi
Reviews23 Dec 2022
Hypertension Research

Volume: 46, P: 589-600

Search

The impact of obstructive sleep apnea and heart rate on arterial stiffness: results from the Tokyo Sleep Heart Study

RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function

Digital hypertension – what we need for the high-quality management of hypertension in the new era

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

Hypertensive disorders of pregnancy and the risk of dementia: a systematic review and meta-analysis of cohort studies

Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis

Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling

A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer

Systolic blood pressure lower than 130 mmHg in heart failure with preserved ejection fraction: a systematic review and meta-analysis of clinical outcomes

Are the cardiovascular outcomes of participants with white-coat hypertension poor compared to those of participants with normotension? A systemic review and meta-analysis

How to manage water and salt intake during the hot summer of 2025

The Relationships of Cardiovascular Disease Risk Factors to Flow-Mediated Dilatation in Japanese Subjects Free of Cardiovascular Disease

Overweight Body Mass Index Classification Modifies Arterial Stiffening Associated with Weight Gain in Healthy Middle-Aged Japanese Men

2023 update and perspectives

The association between the estimated glomerular filtration rate and cognitive impairment: the Suita Study

Nutrition and Hypertension Researches in 2023: focus on salt intake and blood pressure

Concomitant existence and interaction of cardiovascular abnormalities in obstructive sleep apnea subjects with normal clinic blood pressure

Central blood pressure: a powerful predictor of the development of hypertension

Significance of the second peak of systolic blood pressure for identifying both high and low cardiovascular risk states

Association of blood pressure levels with the effects of alcohol intake on the vasculature in Japanese men

The necessity of investigations to clarify sex and racial disparities in pathophysiology of Long COVID

An evidence review project for food with function claims ~Challenges of the Japan society for vascular failure for the promotion of adequate evidences for food with function claims

Reply to: Microvascular hypertensive disease, long COVID, and end-organ pathology

The impacts of secondhand smoke on future generations and the responsibility of society as a whole to protect the well-being of our future descendants

Effectiveness of a computerized clinical decision support system for prevention of glucocorticoid-induced osteoporosis

Differences in longitudinal associations of cardiovascular risk factors with arterial stiffness and pressure wave reflection in middle-aged Japanese men

Long COVID and hypertension-related disorders: a report from the Japanese Society of Hypertension Project Team on COVID-19

Modulation of blood pressure-lowering effects of dark chocolate according to an insulin sensitivity-randomized crossover study

Gender difference in the effects of cacao polyphenols on blood pressure and glucose/lipid metabolism in prediabetic subjects: a double-blinded, randomized, placebo-controlled crossover trial

COVID-19 pandemic and hypertension: an updated report from the Japanese Society of Hypertension project team on COVID-19

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