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Advanced filters: Author: Chongbing Liao Clear advanced filters

Human neutrophil α-defensin HNP1 interacts with bacterial OmpA to promote Acinetobacter baumannii biofilm formation

Acinetobacter baumannii is an opportunistic pathogen that causes nosocomial and community-acquired infections. Here, the authors determine that human neutrophil α-defensin HNP1 can promote A. baumannii biofilm formation.

Chongbing Liao
Qihui Liu
Wuyuan Lu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Shigella infection is facilitated by interaction of human enteric α-defensin 5 with colonic epithelial receptor P2Y11

HD5 induces filopodial extensions in epithelial cells that the pathogen Shigella exploits to facilitate invasion and infection.

Dan Xu
Mengyao Guo
Kai Ye
Research03 Feb 2025
Nature Microbiology

Volume: 10, P: 509-526

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Human neutrophil α-defensin HNP1 interacts with bacterial OmpA to promote Acinetobacter baumannii biofilm formation

Shigella infection is facilitated by interaction of human enteric α-defensin 5 with colonic epithelial receptor P2Y11

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