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Showing 1–7 of 7 results
Advanced filters: Author: Christoph Reiners Clear advanced filters

  • Life expectancy of most patients with differentiated thyroid cancer is normal, so adverse treatment effects should be minimized. Lower activities of radioiodine for ablation of thyroid remnants are non-inferior to higher activities and quality of life can be maintained by preparation of radioiodine remnant ablation using recombinant human thyrotropin.

    • Christoph Reiners
    • Markus Luster
    News & Views
    Nature Reviews Clinical Oncology
    Volume: 9, P: 432-434

  • The treatment of differentiated thyroid carcinoma (DTC) is currently based on initial staging systems that predict mortality. Recurrence, however, is a much larger problem than mortality in DTC. Tuttle et al. have tested the new American Thyroid Association recurrence risk staging system and found that truly accurate staging requires continuous prognostic re-evaluation according to treatment results.

    • Frederik A. Verburg
    • Christoph Reiners
    News & Views
    Nature Reviews Endocrinology
    Volume: 7, P: 127-128

  • Studies published in 2013 have addressed the question of whether the rising incidence of differentiated thyroid cancer is actually the result of overdiagnosis. Advances have also been made in the treatment of differentiated thyroid cancer, including improvements in radioiodine therapy.

    • Christoph Reiners
    News & Views
    Nature Reviews Endocrinology
    Volume: 10, P: 69-70

  • Many questions remain about the efficacy of radioiodine treatment for thyroid remnant ablation and therapy of advanced differentiated thyroid cancer. This Review intends to answer some of these questions taking into account novel insights into the treatment and (re)staging of patients with metastatic disease.

    • Christoph Reiners
    • Heribert Hänscheid
    • Frederik A. Verburg
    Reviews
    Nature Reviews Endocrinology
    Volume: 7, P: 589-595

  • Thyroid ultrasonography is an important element of clinical thyroid diagnostics. Unfortunately, the results of this technique can vary based on the skill and experience of the operator. A new study suggests that assessment of ultrasound images using artificial intelligence has similar sensitivity and improved specificity compared with the judgement of experienced radiologists.

    • Frederik Verburg
    • Christoph Reiners
    News & Views
    Nature Reviews Endocrinology
    Volume: 15, P: 319-321

  • Class I lantibiotic dehydratases play a key role in the biosynthesis of ribosomally synthesized peptide antibiotics. We present structural insights into MadB in two states, revealing the conformational changes that underlie its catalytic mechanism during maddinglicin maturation.

    • C. Vivien Knospe
    • Julio Ortiz
    • Lutz Schmitt
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-12