Various equations have been developed for estimating glomerular filtration rate (GFR), but the issues surrounding GFR estimation are heavily debated. Although many guidelines now recommend the newer MDRD and CKD-EPI equations over the Cockcroft–Gault equation, these equations do fail to provide accurate estimates of GFR in some situations. This article discusses the development of the different equations and describes clinical situations in which the applicability of the equations is questioned.
- Pierre Delanaye
- Christophe Mariat
