Accumulating evidence indicates that NUT carcinoma, a highly aggressive malignancy driven by NUTM1 fusions, is a rare form of squamous cell carcinoma (SCC) of the lung or head and neck, calling into question its current classification as an entirely distinct disease entity. In this Perspective, the authors propose the reclassification of NUT carcinoma as an SCC, the supporting rationale, and the immediate implications for clinical practice and research
- Jia Luo
- Justin A. Bishop
- Christopher A. French