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Showing 51–100 of 108 results

Advanced filters: Author: Christopher D Pond Clear advanced filters

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies

The glycan patch that covers the HIV-1 envelope protein gp120 can be targeted by broadly neutralizing antibodies. Here, Pritchard et al.show that structural changes in the glycans do not significantly hamper antibody recognition, supporting the glycan patch as a stable target for vaccine design.

Laura K. Pritchard
Daniel I.R. Spencer
Max Crispin
Research24 Jun 2015
Nature Communications

Volume: 6, P: 1-11
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2

Individuals over eighty years of age are less likely to mount a good immune response against SARS-CoV-2 (measured by neutralization titres) after the first dose of the BNT162b2 mRNA vaccine, but achieve good neutralization after the second dose.

Dami A. Collier
Isabella A. T. M. Ferreira
Ravindra K. Gupta
ResearchOpen Access30 Jun 2021
Nature

Volume: 596, P: 417-422
Optical coherence tomography evaluation of pulmonary arterial vasculopathy in Systemic Sclerosis

Johannes P. Schwaiger
Christopher D. Loder
John G. Coghlan
ResearchOpen Access24 Feb 2017
Scientific Reports

Volume: 7, P: 1-8
Common genetic variation drives molecular heterogeneity in human iPSCs

Genetic and phenotypic analysis reveals expression quantitative trait loci in human induced pluripotent stem cell lines associated with cancer and disease.

Helena Kilpinen
Angela Goncalves
Daniel J. Gaffney
Research10 May 2017
Nature

Volume: 546, P: 370-375
Enzyme variability in natural populations of Daphnia carinata king

Paul D N Hebert
Christopher Moran
Research01 Dec 1980
Heredity

Volume: 45, P: 313-321
RGD peptides induce apoptosis by direct caspase-3 activation

Christopher D. Buckley
Darrell Pilling
Mike Salmon
Research11 Feb 1999
Nature

Volume: 397, P: 534-539
Magnesium isotope evidence that accretional vapour loss shapes planetary compositions

The measurement of magnesium isotope ratios at improved accuracy suggests that planetary compositions result from fractionation between liquid and vapour, followed by vapour escape during accretionary growth.

Remco C. Hin
Christopher D. Coath
Tim Elliott
Research28 Sept 2017
Nature

Volume: 549, P: 511-515
Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa

Genomic characterization of the SARS-CoV-2 Omicron lineages BA.4 and BA.5, responsible for the fifth COVID-19 pandemic wave in South Africa, shows continued viral diversification and provides insights into the potential mechanisms underlying the ability of the new lineages to outcompete their predecessors.

Houriiyah Tegally
Monika Moir
Tulio de Oliveira
ResearchOpen Access27 Jun 2022
Nature Medicine

Volume: 28, P: 1785-1790
A thermostable, closed SARS-CoV-2 spike protein trimer

The SARS-CoV-2 spike glycoprotein is flexible, and its receptor-binding domain (RBD) fluctuates between open and closed conformations. Disulfide bonds are engineered into the spike ectodomain to lock the RBD in the closed state, leading to a construct with high thermostability.

Xiaoli Xiong
Kun Qu
John A. G. Briggs
Research31 Jul 2020
Nature Structural & Molecular Biology

Volume: 27, P: 934-941
Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes

Cardelino leverages variant information from single-cell RNA-seq data for inferring clonal tree configuration and mapping cells to their clone of origin.

Davis J. McCarthy
Raghd Rostom
Sarah A. Teichmann
Research16 Mar 2020
Nature Methods

Volume: 17, P: 414-421
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp
Dami A. Collier
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E23
Tailings storage facilities, failures and disaster risk

Mine tailings are voluminous and often toxic wastes, whose management is a global safety and sustainability challenge. This Review summarizes the major tailings storage facility disasters and impacts, emphasizing the urgent need for risk reduction approaches for management and policy.

Karen A. Hudson-Edwards
Deanna Kemp
Christopher J. Thomas
Reviews06 Aug 2024
Nature Reviews Earth & Environment

Volume: 5, P: 612-630
Publisher Correction: Shared heritability and functional enrichment across six solid cancers

Xia Jiang
Hilary K. Finucane
Sara Lindström
Amendments and CorrectionsOpen Access23 Sept 2019
Nature Communications

Volume: 10, P: 1-8
Prevalence and architecture of de novo mutations in developmental disorders

Whole-exome analysis of individuals with developmental disorders shows that de novo mutations can equally cause loss or altered protein function, but that most mutations causing altered protein function have not yet been described.

Jeremy F. McRae
Stephen Clayton
Matthew E. Hurles
Research25 Jan 2017
Nature

Volume: 542, P: 433-438
Controls on eDNA movement in streams: Transport, Retention, and Resuspension

Arial J. Shogren
Jennifer L. Tank
Diogo Bolster
ResearchOpen Access11 Jul 2017
Scientific Reports

Volume: 7, P: 1-11
CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Chromodomain Helicase DNA-binding (CHD) proteins have been implicated in neurodevelopmental processes. Here, the authors identify missense variants in CHD3 that disturb its chromatin remodeling activities and cause a neurodevelopmental disorder with macrocephaly and speech and language impairment.

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
ResearchOpen Access05 Nov 2018
Nature Communications

Volume: 9, P: 1-12
Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Dami A. Collier
Anna De Marco
Ravindra K. Gupta
Amendments and Corrections21 Jul 2022
Nature

Volume: 608, P: E24
Herbimycin A accelerates the induction of apoptosis following etoposide treatment or γ-irradiation of bcr/abl-positive leukaemia cells

Fiona A Riordan
Christopher A Bravery
R Gitendra Wickremasinghe
Research01 Apr 1998
Oncogene

Volume: 16, P: 1533-1542
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England

Harald S. Vöhringer
Theo Sanderson
Moritz Gerstung
Amendments and CorrectionsOpen Access07 Jun 2022
Nature

Volume: 606, P: E18
A comparison of coastal habitat restoration projects in China and the United States

Shanze Li
Tian Xie
Mingming Hu
ResearchOpen Access07 Oct 2019
Scientific Reports

Volume: 9, P: 1-10
Recent Arctic tundra fire initiates widespread thermokarst development

Benjamin M. Jones
Guido Grosse
Christopher F. Larsen
ResearchOpen Access29 Oct 2015
Scientific Reports

Volume: 5, P: 1-13
Reproductive characteristics of American bullfrogs (Lithobates catesbeianus) in their invasive range of the Pacific Northwest, USA

Jenny Urbina
Evan M. Bredeweg
Tiffany S. Garcia
ResearchOpen Access01 Oct 2020
Scientific Reports

Volume: 10, P: 1-8
Leads in Arctic pack ice enable early phytoplankton blooms below snow-covered sea ice

Philipp Assmy
Mar Fernández-Méndez
Mats A. Granskog
ResearchOpen Access19 Jan 2017
Scientific Reports

Volume: 7, P: 1-9
SARS-CoV-2 viral titer measurements in Ontario, Canada wastewaters throughout the COVID-19 pandemic

Patrick M. D’Aoust
Nada Hegazy
Robert Delatolla
ResearchOpen Access21 Jun 2024
Scientific Data

Volume: 11, P: 1-13
The viability and desirability of replacing palm oil

Increasing concerns about the impacts of palm oil cultivation have led to a growing focus on how to replace palm oil in commercial applications. This Perspective analyses replacement options—from a technical, environmental and economic angle—and how to make current cultivation practices more sustainable.

Sophie Parsons
Sofia Raikova
Christopher J. Chuck
Reviews09 Mar 2020
Nature Sustainability

Volume: 3, P: 412-418
Vertical accretion trends project doughnut-like fragmentation of saltmarshes

Barrier-island associated saltmarshes are accreting at differential rates across marsh platforms, such that fragmentation is likely as marsh edges keep pace with sea-level rise as interiors drown, according to analyses of sediment cores sampled in the eastern USA.

Christopher J. Hein
Jennifer E. Connell
Kendall King
ResearchOpen Access09 Feb 2024
Communications Earth & Environment

Volume: 5, P: 1-12
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Brian J. Willett
Joe Grove
Emma C. Thomson
Amendments and CorrectionsOpen Access16 Sept 2022
Nature Microbiology

Volume: 7, P: 1709
Broadband radiometric measurements from GPS satellites reveal summertime Arctic Ocean Albedo decreases more rapidly than sea ice recedes

Philip L. Dreike
Amy K. Kaczmarowski
Mark Ivey
ResearchOpen Access23 Aug 2023
Scientific Reports

Volume: 13, P: 1-12
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Dehydration-Rehydration Vesicles: A Simple Method for High Yield Drug Entrapment in Liposomes

Christopher Kirby
Gregory Gregoriadis
Research01 Nov 1984
Bio/Technology

Volume: 2, P: 979-984
Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology

Cope, Elsborg et al. analyzed transcriptomic data from mice and astronauts flown to space and identified molecular signatures of DNA damage and repair, mitochondrial dysregulation, and skin barrier disruption. These changes may underpin dermatological issues in astronauts.

Henry Cope
Jonas Elsborg
Afshin Beheshti
ResearchOpen Access11 Jun 2024
Communications Medicine

Volume: 4, P: 1-18
Structural and compositional characteristics of Fukushima release particulate material from Units 1 and 3 elucidates release mechanisms, accident chronology and future decommissioning strategy

Peter G. Martin
Christopher P. Jones
Thomas B. Scott
ResearchOpen Access16 Dec 2020
Scientific Reports

Volume: 10, P: 1-17
Localized iron accumulation precedes nucleation and growth of magnetite crystals in magnetotactic bacteria

Jacques Werckmann
Jefferson Cypriano
Marcos Farina
ResearchOpen Access15 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
Racial disparities in prostate cancer in the UK and the USA: similarities, differences and steps forwards

Examination of racial disparities in prostate cancer in the USA and UK highlights systemic, socio-economic and sociocultural factors that might contribute to these differences. Understanding behavioural medicine might inform and improve the way in which the health-care system can engage with patients in minorities who are affected by this disease.

Edward Christopher Dee
Rebecca Todd
Paul L. Nguyen
Reviews18 Oct 2024
Nature Reviews Urology

Volume: 22, P: 223-234
Four distinct Northeast US heat wave circulation patterns and associated mechanisms, trends, and electric usage

Laurie Agel
Mathew Barlow
Judah Cohen
ResearchOpen Access27 May 2021
npj Climate and Atmospheric Science

Volume: 4, P: 1-11
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

James H. R. Farmery
Mike L. Smith
Andy G. Lynch
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-17
Emotional face processing across neurodevelopmental disorders: a dynamic faces study in children with autism spectrum disorder, attention deficit hyperactivity disorder and obsessive-compulsive disorder

Marlee M. Vandewouw
EunJung Choi
Margot J. Taylor
ResearchOpen Access02 Nov 2020
Translational Psychiatry

Volume: 10, P: 1-12
Next generation sequencing data of a defined microbial mock community

Esther Singer
Bill Andreopoulos
Tanja Woyke
ResearchOpen Access27 Sept 2016
Scientific Data

Volume: 3, P: 1-8
Water supply and sanitation services in small towns in rural–urban transition zones: The case of Bushenyi-Ishaka Municipality, Uganda

Sara J. Marks
Guillaume Clair-Caliot
Giuliana Ferrero
ResearchOpen Access27 Apr 2020
npj Clean Water

Volume: 3, P: 1-9
Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp

Zhenjian Lin
Michael Koch
Eric W Schmidt
Research13 Nov 2013
The Journal of Antibiotics

Volume: 67, P: 121-126
The impact of catch-up bivalent human papillomavirus vaccination on cervical screening outcomes: an observational study from the English HPV primary screening pilot

Matejka Rebolj
Francesca Pesola
Henry Kitchener
ResearchOpen Access26 Mar 2022
British Journal of Cancer

Volume: 127, P: 278-287
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study

Kerstin Kläser
Erika Molteni
Emma L. Duncan
ResearchOpen Access28 Jun 2022
Scientific Reports

Volume: 12, P: 1-17
Researchers as Educators: New Legislation Compels a Stronger Role

Christopher Edwards
Editorial01 Jul 1983
Bio/Technology

Volume: 1, P: 387
Water quality measurements in Buzzards Bay by the Buzzards Bay Coalition Baywatchers Program from 1992 to 2018

Rachel W. Jakuba
Tony Williams
Mark Rasmussen
ResearchOpen Access05 Mar 2021
Scientific Data

Volume: 8, P: 1-11
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
Amendments and CorrectionsOpen Access15 Feb 2019
Nature Communications

Volume: 10, P: 1-4
Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

Lot Snijders Blok
Justine Rousseau
Philippe M. Campeau
Amendments and CorrectionsOpen Access02 May 2019
Nature Communications

Volume: 10, P: 1-4
Phosphate-regulated expression of the SARS-CoV-2 receptor-binding domain in the diatom Phaeodactylum tricornutum for pandemic diagnostics

Samuel S. Slattery
Daniel J. Giguere
David R. Edgell
ResearchOpen Access29 Apr 2022
Scientific Reports

Volume: 12, P: 1-15
Mouse models of immune dysfunction: their neuroanatomical differences reflect their anxiety-behavioural phenotype

Darren J. Fernandes
Shoshana Spring
Jason P. Lerch
ResearchOpen Access14 Apr 2022
Molecular Psychiatry

Volume: 27, P: 3047-3055
All-Optical Rotational Ultrasound Imaging

Richard J. Colchester
Callum Little
Adrien E. Desjardins
ResearchOpen Access03 Apr 2019
Scientific Reports

Volume: 9, P: 1-8
Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder

Christie L. Burton
Mathieu Lemire
Paul D. Arnold
ResearchOpen Access02 Feb 2021
Translational Psychiatry

Volume: 11, P: 1-10

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