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Showing 1–3 of 3 results
Advanced filters: Author: Curtis M. Schauder Clear advanced filters

  • Saheki and colleagues show that extended synaptotagmins (E-Syts), ER proteins that function as tethers to the plasma membrane, can transfer lipids between bilayers in a Ca2+- and SMP-domain-dependent manner, thus regulating plasma membrane lipid homeostasis.

    • Yasunori Saheki
    • Xin Bian
    • Pietro De Camilli
    Research
    Nature Cell Biology
    Volume: 18, P: 504-515

  • Several proteins localized at membrane contact sites contain an SMP domain, which has been proposed to act as a lipid-binding module; here, the crystal structure of a fragment of the extended synaptotagmin 2 protein, including its SMP, is presented, and indicates that this protein may have a direct role in lipid transport.

    • Curtis M. Schauder
    • Xudong Wu
    • Karin M. Reinisch
    Research
    Nature
    Volume: 510, P: 552-555