Casali, Tognolina et al. use two-photon laser microscopy to spatially map long-term synaptic plasticity in rat cerebellar granular cells following stimulation of mossy fibers. Their data allow them to apply realistic modeling to test hypotheses about the synaptic spiking dynamics and reveal the importance of synaptic inhibition to defining these microcircuits.
- Stefano Casali
- Marialuisa Tognolina
- Egidio D’Angelo