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Showing 1–50 of 120 results

Advanced filters: Author: D Ehninger Clear advanced filters

Pharmacokinetics of mitoxantrone in cancer patients treated by high-dose chemotherapy and autologous bone marrow transplantation

B Richard
MC Launay-Iliadis
Y Carcassonne
Research01 Mar 1992
British Journal of Cancer

Volume: 65, P: 399-404
Change in Entropy During Bacterial Metabolism

W. W. FORREST
D. J. WALKER
Research04 Jan 1964
Nature

Volume: 201, P: 49-52
Reduction-potential of Glutathione

J. ROST
S. RAPOPORT
Research11 Jan 1964
Nature

Volume: 201, P: 185
Networking in Autism: Leveraging Genetic, Biomarker and Model System Findings in the Search for New Treatments

Jeremy Veenstra-VanderWeele
Randy D Blakely
Reviews21 Sept 2011
Neuropsychopharmacology

Volume: 37, P: 196-212
Mutations causing syndromic autism define an axis of synaptic pathophysiology

The mutations that underlie the diseases tuberous sclerosis complex and fragile X syndrome produce abnormalities in synaptic plasticity and function that can be corrected by treatments that modulate metabotropic glutamate receptor 5 in opposite directions.

Benjamin D. Auerbach
Emily K. Osterweil
Mark F. Bear
Research23 Nov 2011
Nature

Volume: 480, P: 63-68
Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC η with MDR1, MRP and LRP gene expression

J Beck
B Bohnet
V Gekeler
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 87-91
The influence of 1-β- D-arabinofuranosylcytosine on the metabolism of phosphatidylcholine in human leukemic HL 60 and Raji cells

D Berkovic
EAM Fleer
W Hiddemann
Research01 Dec 1997
Leukemia

Volume: 11, P: 2079-2086
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

Proteasomal degradation of EZH2 in AML patients in response to therapy triggers the expression of stem cell markers and has been identified as an epigenetic pathway leading to acquired drug resistance. Treatments aimed to restore EZH2 expression in relapsed AML patients have shown clinical efficacy and constitute a viable approach to re-sensitize tumors to chemotherapy.

Stefanie Göllner
Thomas Oellerich
Carsten Müller-Tidow
Research12 Dec 2016
Nature Medicine

Volume: 23, P: 69-78
Actin-nucleation promoting factor N-WASP influences alpha-synuclein condensates and pathology

Joshua Jackson
Christian Hoffmann
Daniele Bano
ResearchOpen Access30 Apr 2024
Cell Death & Disease

Volume: 15, P: 1-17
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5

Hassan Mziaut
Mirko Trajkovski
Michele Solimena
Research16 Apr 2006
Nature Cell Biology

Volume: 8, P: 435-445
Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome

Noonan syndrome (NS) is an autosomal dominant genetic disease that is co-morbid with cognitive deficits in a subset of patients. Using mouse models of NS, a study now shows that the synaptic plasticity and memory deficits in mouse models of NS are due primarily to the dysfunction in the MEK-Erk kinase pathways, and pharmacological intervention that alters MEK-Ras function can alleviate physiological and behavioral deficits in the mouse models of NS.

Yong-Seok Lee
Dan Ehninger
Alcino J Silva
Research10 Nov 2014
Nature Neuroscience

Volume: 17, P: 1736-1743
Longitudinal fluctuations in cytomegalovirus load in bone marrow transplant patients: relationship between peak virus load, donor/recipient serostatus, acute GVHD and CMV disease

D Gor
C Sabin
VC Emery
Research24 Mar 1998
Bone Marrow Transplantation

Volume: 21, P: 597-605
Hematopoietic stem cell transplantation with unrelated cord blood or haploidentical donor grafts in adult patients with secondary acute myeloid leukemia, a comparative study from Eurocord and the ALWP EBMT

Annalisa Ruggeri
Myriam Labopin
Arnon Nagler
Research31 May 2019
Bone Marrow Transplantation

Volume: 54, P: 1987-1994
Influence of HLA on human partnership and sexual satisfaction

J. Kromer
T. Hummel
I. Croy
ResearchOpen Access31 Aug 2016
Scientific Reports

Volume: 6, P: 1-6
Umbilical cord blood versus unrelated donor transplantation in adults with primary refractory or relapsed acute myeloid leukemia: a report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the EBMT

Frédéric Baron
Myriam Labopin
Arnon Nagler
ResearchOpen Access12 Apr 2019
Blood Cancer Journal

Volume: 9, P: 1-7
BCAT1 restricts αKG levels in AML stem cells leading to IDH^mut-like DNA hypermethylation

The mechanistic basis for the role of the metabolic enzyme BCAA transaminase 1 (BCAT1) in acute myeloid leukaemias.

Simon Raffel
Mattia Falcone
Andreas Trumpp
Research08 Nov 2017
Nature

Volume: 551, P: 384-388
High-dose mitoxantrone with peripheral blood progenitor cell rescue: toxicity, pharmacokinetics and implications for dosage and schedule

A Ballestrero
F Ferrando
F Patrone
Research01 Sept 1997
British Journal of Cancer

Volume: 76, P: 797-804
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDH^mut-like DNA hypermethylation

Simon Raffel
Mattia Falcone
Andreas Trumpp
Amendments and Corrections01 Aug 2018
Nature

Volume: 560, P: E28
Awakening dormant haematopoietic stem cells

Haematopoietic stem cells (HSCs) can reside as dormant cells in endosteal niches in the bone marrow, where they are resistant to certain types of chemotherapy. In this article, the authors suggest that by first awakening dormant HSCs to become actively self-renewing cells, this resistance to chemotherapy could be overcome.

Andreas Trumpp
Marieke Essers
Anne Wilson
Reviews01 Mar 2010
Nature Reviews Immunology

Volume: 10, P: 201-209
Session I: Nonmyeloablative stem cell transplantation and adoptive immunotherapy (1)

D Huhn
R Storb
News22 Jun 1999
Bone Marrow Transplantation

Volume: 23, P: S3
Second allogeneic bone marrow transplantation in acute leukemia: a multicenter study from the Gruppo Italiano Trapianto Di Midollo Osseo (GITMO)

A Bosi
S Bacci
A Amici
Research01 Mar 1997
Leukemia

Volume: 11, P: 420-424
Extracorporeal photopheresis (ECP) in the treatment of chronic graft-versus-host disease (GVHD)

FJ Child
R Ratnavel
R Russell-Jones
Research07 May 1999
Bone Marrow Transplantation

Volume: 23, P: 881-887
Comparison of cytomegalovirus antigenemia and shell vial culture in allogeneic marrow transplantation recipients receiving ganciclovir prophylaxis

VA Nicholson
E Whimbey
JM Goodrich
Research01 Jan 1997
Bone Marrow Transplantation

Volume: 19, P: 37-41
Erratum: JAK2-V617F activating mutation in acute myeloid leukemia: prognostic impact and association with other molecular markers

C Vicente
I Vázquez
M D Odero
Amendments and Corrections21 Nov 2007
Leukemia

Volume: 21, P: 2576
Use of intravenous immune globulin in addition to antiviral therapy in the treatment of CMV gastrointestinal disease in allogeneic bone marrow transplant patients: a report from the European Group for Blood and Marrow Transplantation (EBMT)

P Ljungman
C Cordonnier
D Veil
Research12 Mar 1998
Bone Marrow Transplantation

Volume: 21, P: 473-476
Hematopoietic cell transplantation in patients with intermediate and high-risk AML: results from the randomized Study Alliance Leukemia (SAL) AML 2003 trial

J Schetelig
M Schaich
G Ehninger
Research01 Dec 2014
Leukemia

Volume: 29, P: 1060-1068
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice

D P Ryan
K S Henzel
D Ehninger
ResearchOpen Access04 Apr 2017
Molecular Psychiatry

Volume: 23, P: 1345-1355
Value of cytomegalovirus detection by PCR in bronchoalveolar lavage routinely performed in asymptomatic bone marrow recipients

A Fajac
F Stéphan
JL Pico
Research01 Oct 1997
Bone Marrow Transplantation

Volume: 20, P: 581-585
Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia

R M Stone
T Fischer
F Giles
Research27 Apr 2012
Leukemia

Volume: 26, P: 2061-2068
Prevention of relapse in pediatric patients with acute leukemias and MDS after allogeneic SCT by early immunotherapy initiated on the basis of increasing mixed chimerism: a single center experience of 12 children

P Bader
T Klingebiel
JF Beck
Research02 Dec 1999
Leukemia

Volume: 13, P: 2079-2086
Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial

Christoph Röllig
Hubert Serve
Gerhard Ehninger
ResearchOpen Access18 Feb 2021
Leukemia

Volume: 35, P: 2517-2525
Induction of MDR1 gene expression by anthracycline analogues in a human drug resistant leukaemia cell line

X F Hu
A Slater
J Zalcberg
ResearchOpen Access29 Jan 1999
British Journal of Cancer

Volume: 79, P: 831-837
Quantitative lymphocyte subset reconstitution after allogeneic hematopoietic transplantation from matched related donors with CD34⁺ selected PBPC grafts, unselected PBPC grafts or BM grafts

D Behringer
H Bertz
J Finke
Research23 Jul 1999
Bone Marrow Transplantation

Volume: 24, P: 295-302
Reduced-intensity conditioning with busulfan and fludarabine with or without antithymocyte globulin in HLA-identical sibling transplantation – a retrospective analysis

J Schetelig
M Bornhäuser
W Siegert
Research29 Dec 2003
Bone Marrow Transplantation

Volume: 33, P: 483-490
HLA-identical sibling allogeneic peripheral blood stem cell transplantation with reduced intensity conditioning compared to autologous peripheral blood stem cell transplantation for elderly patients with de novo acute myeloid leukemia

A-L Herr
M Labopin
V Rocha
Research23 Nov 2006
Leukemia

Volume: 21, P: 129-135
Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia

Jan-Niklas Eckardt
Sebastian Stasik
Christian Thiede
ResearchOpen Access13 Oct 2023
Leukemia

Volume: 37, P: 2395-2403
A toolbox for the longitudinal assessment of healthspan in aging mice

A series of techniques (echocardiography, novel object recognition, grip strength, rotarod, glucose and insulin tolerance tests, body composition, and energy expenditure) are used to assess the health of mice.

I. Bellantuono
R. de Cabo
D. W. Lamming
Protocols08 Jan 2020
Nature Protocols

Volume: 15, P: 540-574
MN1–Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells

D V Wenge
E Felipe-Fumero
J-H Mikesch
ResearchOpen Access21 Dec 2015
Oncogenesis

Volume: 4, P: e179
Prognostic impact of CEBPA mutational subgroups in adult AML

Julia-Annabell Georgi
Sebastian Stasik
Christian Thiede
ResearchOpen Access16 Jan 2024
Leukemia

Volume: 38, P: 281-290
Acute myeloid leukaemia

Acute myeloid leukaemia is characterized by clonal proliferation of haematopoietic stem cells or progenitor cells, leading to fewer differentiated red blood cells, platelets and white blood cells. The disease presents with a rapid onset and may be fatal in weeks or months if left untreated.

Asim Khwaja
Magnus Bjorkholm
David C. Linch
Reviews10 Mar 2016
Nature Reviews Disease Primers

Volume: 2, P: 1-22
German consensus on immunogenetic donor search for transplantation of allogeneic bone marrow and peripheral blood stem cells

HD Ottinger
E Albert
H Grosse-Wilde
Research01 Jul 1997
Bone Marrow Transplantation

Volume: 20, P: 101-105
Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

Laura Cicconi
Uwe Platzbecker
Francesco Lo-Coco
Research14 Oct 2019
Leukemia

Volume: 34, P: 914-918
Comparable survival using a CMV-matched or a mismatched donor for CMV+ patients undergoing T-replete haplo-HSCT with PT-Cy for acute leukemia: a study of behalf of the infectious diseases and acute leukemia working parties of the EBMT

Simone Cesaro
Roberto Crocchiolo
Jan Styczynski
Research12 Jan 2018
Bone Marrow Transplantation

Volume: 53, P: 422-430
Reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia: disease status by marrow blasts is the strongest prognostic factor

H G Sayer
M Kröger
M Bornhäuser
Research10 Jun 2003
Bone Marrow Transplantation

Volume: 31, P: 1089-1095
Neonatal Varicella

Andreas Sauerbrei
Peter Wutzler
Reviews02 Jan 2002
Journal of Perinatology

Volume: 21, P: 545-549
Unmanipulated haploidentical versus HLA-matched sibling allogeneic hematopoietic stem cell transplantation in relapsed/refractory acute myeloid leukemia: a retrospective study on behalf of the ALWP of the EBMT

Giorgia Battipaglia
Ariane Boumendil
Arnon Nagler
Research04 Feb 2019
Bone Marrow Transplantation

Volume: 54, P: 1499-1510
¹³¹I-metaiodobenzylguanidine (¹³¹I-MIBG) therapy for residual neuroblastoma: a mono-institutional experience with 43 patients

A Garaventa
O Bellagamba
B De Bernardi
ResearchOpen Access26 Nov 1999
British Journal of Cancer

Volume: 81, P: 1378-1384
R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice

Laura J Stoppel
Tatiana M Kazdoba
Mark F Bear
ResearchOpen Access06 Oct 2017
Neuropsychopharmacology

Volume: 43, P: 513-524
Net reclassification improvement with serial biomarkers and bed-sided spirometry to early predict the need of organ support during the early post-transplantation in-hospital stay in allogeneic HCT recipients

S. D. Braun
M. Kuhn
M. Bornhäuser
Research21 Jun 2018
Bone Marrow Transplantation

Volume: 54, P: 265-274
Mobilization of peripheral blood stem cells for autologous transplant in non-Hodgkin's lymphoma and multiple myeloma patients by plerixafor and G-CSF and detection of tumor cell mobilization by PCR in multiple myeloma patients

S Fruehauf
G Ehninger
G Calandra
Research13 Jul 2009
Bone Marrow Transplantation

Volume: 45, P: 269-275

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