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Showing 401–450 of 490 results

Advanced filters: Author: D Grail Clear advanced filters

Genetic analysis identifies putative tumor suppressor sites at 2q35–q36.1 and 2q36.3–q37.1 involved in cervical cancer progression

Gopeshwar Narayan
Hugo Arias Pulido
Vundavalli VVS Murty
Research29 May 2003
Oncogene

Volume: 22, P: 3489-3499
The FHIT gene is alternatively spliced in normal kidney and renal cell carcinoma

Xudong Luan
Guangping Shi
Linda A Cannizzaro
Research03 Jul 1997
Oncogene

Volume: 15, P: 79-86
A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorder

D Goossens
S Van Gestel
J Del-Favero
Research30 Jan 2003
Molecular Psychiatry

Volume: 8, P: 83-89
Strategies for the successful implementation of plasma-based NSCLC genotyping in clinical practice

Genotyping is recommended for all patients with metastatic non-squamous non-small-cell lung cancers (NSCLC), both to enable patients to receive targeted therapies and to avoid therapies they are unlikely to benefit from. However, obtaining tumour biopsy material for genotyping is often challenging and is unfeasible in some patients, indicating the need to incorporate liquid biopsy approaches. In this Perspective, the authors provide guidance on how analysis of ctDNA from liquid biopsy samples in patients with metastatic NSCLC prior to first-line therapy has the potential to extend the benefits of genotyping to virtually all patients.

Charu Aggarwal
Christian D. Rolfo
David R. Gandara
Reviews11 Sept 2020
Nature Reviews Clinical Oncology

Volume: 18, P: 56-62
Machine learning-based prediction of microsatellite instability and high tumor mutation burden from contrast-enhanced computed tomography in endometrial cancers

Harini Veeraraghavan
Claire F. Friedman
Yulia Lakhman
ResearchOpen Access20 Oct 2020
Scientific Reports

Volume: 10, P: 1-10
Mosaic chromosomal alterations (mCAs) in individuals with monoclonal B-cell lymphocytosis (MBL)

Aswin Sekar
Rosalie Griffin
Susan L. Slager
ResearchOpen Access06 Nov 2024
Blood Cancer Journal

Volume: 14, P: 1-8
Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer

Julie E. Lang
Andres Forero-Torres
Laura J. Esserman
ResearchOpen Access01 Dec 2022
npj Breast Cancer

Volume: 8, P: 1-10
Cell-free DNA analysis in current cancer clinical trials: a review

M. Cisneros-Villanueva
L. Hidalgo-Pérez
A. Hidalgo-Miranda
ReviewsOpen Access13 Jan 2022
British Journal of Cancer

Volume: 126, P: 391-400
MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia

Brooke M Emerling
Jeannette Bonifas
Kevin M Shannon
Research09 Jul 2002
Oncogene

Volume: 21, P: 4849-4854
Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers

Angelo Agathanggelou
Ashraf Dallol
Farida Latif
Research11 Mar 2003
Oncogene

Volume: 22, P: 1580-1588
Potential use of the alkaline comet assay as a predictor of bladder tumour response to radiation

S R McKeown
T Robson
V J McKelvey-Martin
ResearchOpen Access12 Dec 2003
British Journal of Cancer

Volume: 89, P: 2264-2270
UBD, a downstream element of FOXP3, allows the identification of LGALS3, a new marker of human regulatory T cells

Frank Ocklenburg
Darius Moharregh-Khiabani
Michael Probst-Kepper
Research15 May 2006
Laboratory Investigation

Volume: 86, P: 724-737
CoRRE Trait Data: A dataset of 17 categorical and continuous traits for 4079 grassland species worldwide

Kimberly J. Komatsu
Meghan L. Avolio
Kevin Wilcox
ResearchOpen Access18 Jul 2024
Scientific Data

Volume: 11, P: 1-13
Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma

Patients with early stage hepatocellular carcinoma typically undergo resection, liver transplantation or local ablation; however, 30–50% will have disease recurrence at 3 years. The authors of this Review describe the tumour immune microenvironment and mechanism of action of immunotherapies, and discuss the available evidence from phase II/III trials of neoadjuvant and adjuvant treatment approaches in this setting.

Josep M. Llovet
Roser Pinyol
Richard S. Finn
Reviews29 Feb 2024
Nature Reviews Clinical Oncology

Volume: 21, P: 294-311
Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

Hepatocellular carcinoma (HCC) is among the most common causes of cancer-related death globally, and despite improvements in prevention and treatment strategies, continued increases in HCC incidence and mortality are predicted. Cirrhosis remains the major risk factor for HCC, although the underlying aetiology is shifting from virus-related to non-viral liver diseases. In this Review, the authors discuss the changing trends in HCC epidemiology and their implications for screening, prevention and therapy, including opportunities to further improve the management of patients with, or at high risk of, HCC.

Amit G. Singal
Fasiha Kanwal
Josep M. Llovet
Reviews26 Oct 2023
Nature Reviews Clinical Oncology

Volume: 20, P: 864-884
Controlling NF-κB activation in T cells by costimulatory receptors

M L Schmitz
D Krappmann
Reviews13 Jan 2006
Cell Death & Differentiation

Volume: 13, P: 834-842
Identifying blood biomarkers for mood disorders using convergent functional genomics

H Le-Niculescu
S M Kurian
A B Niculescu
Research26 Feb 2008
Molecular Psychiatry

Volume: 14, P: 156-174
Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

In this Review, Llovet and colleagues discuss advances in our knowledge of the pathogenesis and clinical management of nonalcoholic steatohepatitis-related hepatocellular carcinoma. They also discuss future prospects and unmet needs.

Josep M. Llovet
Catherine E. Willoughby
Scott L. Friedman
Reviews17 Mar 2023
Nature Reviews Gastroenterology & Hepatology

Volume: 20, P: 487-503
A global database for metacommunity ecology, integrating species, traits, environment and space

Alienor Jeliazkov
Darko Mijatovic
Jonathan M. Chase
ResearchOpen Access08 Jan 2020
Scientific Data

Volume: 7, P: 1-15
Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer

Lillian M. Smyth
Gerald Batist
Sarat Chandarlapaty
ResearchOpen Access16 Apr 2021
npj Breast Cancer

Volume: 7, P: 1-7
The biological consequences of excess GM-CSF levels in transgenic mice also lacking high-affinity receptors for GM-CSF

D Metcalf
S Mifsud
W Alexander
Research30 Apr 1998
Leukemia

Volume: 12, P: 353-362
Safety analyses from the phase 3 ASCENT trial of sacituzumab govitecan in metastatic triple-negative breast cancer

Hope S. Rugo
Sara M. Tolaney
Kevin Kalinsky
ResearchOpen Access29 Aug 2022
npj Breast Cancer

Volume: 8, P: 1-10
Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique

Emily J. Gallagher
Heather Moore
Michael S. Broder
ResearchOpen Access31 Jan 2024
npj Breast Cancer

Volume: 10, P: 1-11
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Zuzana Kos
Elvire Roblin
Zsuzsanna Bago-Horvath
ResearchOpen Access12 May 2020
npj Breast Cancer

Volume: 6, P: 1-16
Cardiac outcomes of subjects on adjuvant trastuzumab emtansine vs paclitaxel in combination with trastuzumab for stage I HER2-positive breast cancer (ATEMPT) study (TBCRC033): a randomized controlled trial

Romualdo Barroso-Sousa
Paolo Tarantino
Sara M. Tolaney
ResearchOpen Access16 Feb 2022
npj Breast Cancer

Volume: 8, P: 1-7
Lymphoid abnormalities in CD40 ligand transgenic mice suggest the need for tight regulation in gene therapy approaches to hyper immunoglobulin M (IgM) syndrome

Maria Grazia Sacco
Marco Ungari
Paolo Vezzoni
Research01 Oct 2000
Cancer Gene Therapy

Volume: 7, P: 1299-1306
Some factors which affect the visual outcome of corneal transplantation

D J Coster
Research01 May 1991
Eye

Volume: 5, P: 265-278
Scalable and robust SARS-CoV-2 testing in an academic center

Jim Aitken
Karen Ambrose
Rachel Zillwood
Correspondence18 Jun 2020
Nature Biotechnology

Volume: 38, P: 927-931
Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management

Mafalda Antunes-Ferreira
Silvia D’Ambrosi
Thomas Wurdinger
ResearchOpen Access08 Jun 2023
Scientific Reports

Volume: 13, P: 1-12
Superluminal X-waves in a polariton quantum fluid

Antonio Gianfrate
Lorenzo Dominici
Daniele Sanvitto
ResearchOpen Access16 Aug 2017
Light: Science & Applications

Volume: 7, P: 17119
Hepatocellular carcinoma

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, is one of the leading causes of cancer-related death in the world. This Primer summarizes the current knowledge on the epidemiology, pathogenetic mechanisms and diagnosis of HCC and provides an update on key advancements in the management of this disease.

Josep M. Llovet
Robin Kate Kelley
Richard S. Finn
Reviews21 Jan 2021
Nature Reviews Disease Primers

Volume: 7, P: 1-28
Transcriptional regulation by MYC: an emerging new model

Simon T. Jakobsen
Rasmus Siersbæk
Reviews28 Oct 2024
Oncogene

Volume: 44, P: 1-7
Correction: Modelled mortality benefits of multi-cancer early detection screening in England

Peter Sasieni
Rebecca Smittenaar
Charles Swanton
Amendments and CorrectionsOpen Access18 Nov 2024
British Journal of Cancer

Volume: 131, P: 1942-1944
A Phase 1B open-label study of gedatolisib (PF-05212384) in combination with other anti-tumour agents for patients with advanced solid tumours and triple-negative breast cancer

Giuseppe Curigliano
Geoffrey I. Shapiro
Zev A. Wainberg
Research05 Nov 2022
British Journal of Cancer

Volume: 128, P: 30-41
Depletion of naive T cells using clinical grade magnetic CD45RA beads: a new approach for GVHD prophylaxis

D Teschner
E Distler
W Herr
Research12 Aug 2013
Bone Marrow Transplantation

Volume: 49, P: 138-144
DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC

Harry A Drabkin
James D West
Fred Sablitzky
Research27 Apr 1999
Oncogene

Volume: 18, P: 2589-2597
Biotech leaders call for free press

Ron Cohen
Steven Holtzman
Sanford Sandy Zweifach
Correspondence01 Oct 2018
Nature Biotechnology

Volume: 36, P: 920-922
Imagining the future of optical microscopy: everything, everywhere, all at once

A high-level perspective on the future of live imaging is presented, with a vision to image anything in a biological sample, anywhere and at any time. A particular focus is given to current challenges and strategies to overcome them.

Harikrushnan Balasubramanian
Chad M. Hobson
Jesse S. Aaron
ReviewsOpen Access28 Oct 2023
Communications Biology

Volume: 6, P: 1-12
Sacituzumab govitecan as second-line treatment for metastatic triple-negative breast cancer—phase 3 ASCENT study subanalysis

Lisa A. Carey
Delphine Loirat
Javier Cortés
ResearchOpen Access09 Jun 2022
npj Breast Cancer

Volume: 8, P: 1-7
Efficacy and safety of rucaparib treatment in patients with BRCA-mutated, relapsed ovarian cancer: final results from Study 10

Rebecca S. Kristeleit
Yvette Drew
Ronnie Shapira-Frommer
Research08 Dec 2022
British Journal of Cancer

Volume: 128, P: 255-265
Toxicity Index, patient-reported outcomes, and persistence of breast cancer chemotherapy-associated side effects in NRG Oncology/NSABP B-30

N. Lynn Henry
Sungjin Kim
Patricia A. Ganz
ResearchOpen Access19 Nov 2022
npj Breast Cancer

Volume: 8, P: 1-7
A case-control study to evaluate the impact of the breast screening programme on mortality in England

Roberta Maroni
Nathalie J. Massat
Stephen W. Duffy
ResearchOpen Access23 Nov 2020
British Journal of Cancer

Volume: 124, P: 736-743
Genetic contributions to self-reported tiredness

V Deary
S P Hagenaars
I J Deary
ResearchOpen Access14 Feb 2017
Molecular Psychiatry

Volume: 23, P: 609-620
Circulating tumor cell number and endocrine therapy index in ER positive metastatic breast cancer patients

Costanza Paoletti
Meredith M. Regan
Daniel F. Hayes
ResearchOpen Access11 Jun 2021
npj Breast Cancer

Volume: 7, P: 1-9
Years of life lost due to cancer in the United Kingdom from 1988 to 2017

Amar S. Ahmad
Judith Offman
Peter D. Sasieni
ResearchOpen Access19 Sept 2023
British Journal of Cancer

Volume: 129, P: 1558-1568
Primary care providers’ responses to unsolicited Lynch syndrome secondary findings of varying clinical significance

Lauren N. Galbraith
Charlene L. Preys
Kurt D. Christensen
Research10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1977-1983
Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab

Emanuela Ferraro
Jasmeet Singh
Chau T. Dang
ResearchOpen Access22 Mar 2022
npj Breast Cancer

Volume: 8, P: 1-8
The clinical behavior and genomic features of the so-called adenoid cystic carcinomas of the solid variant with basaloid features

Christopher J. Schwartz
Edi Brogi
Hannah Y. Wen
Research01 Oct 2021
Modern Pathology

Volume: 35, P: 193-201
NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2^V617F-positive myeloproliferative neoplasm cells

Bruna Alves Fenerich
Jaqueline Cristina Fernandes
Fabiola Traina
ResearchOpen Access24 Jan 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-10
Psychological outcomes related to exome and genome sequencing result disclosure: a meta-analysis of seven Clinical Sequencing Exploratory Research (CSER) Consortium studies

Jill O. Robinson
Julia Wynn
Stacy W. Gray
Research13 Jun 2019
Genetics in Medicine

Volume: 21, P: 2781-2790

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