Nature Search

Further Observations on the Effects of Tumours on the Perchloric Acid Soluble Proteins of the Rat

D Burston
M E Apsey
N F Maclagan
Research01 Mar 1965
British Journal of Cancer

Volume: 19, P: 200-210
Quantitative self-assembly prediction yields targeted nanomedicines

Molecular simulations reveal the self-assembly of small molecules into nanoparticle drug carriers. Targeting of colon and liver cancer cells by the nanoparticles via kinase inhibitors is employed in anti-tumour therapy in vivo.

Yosi Shamay
Janki Shah
Daniel A. Heller
Research05 Feb 2018
Nature Materials

Volume: 17, P: 361-368
Data-driven electron-diffraction approach reveals local short-range ordering in CrCoNi with ordering effects

Non-random chemical mixings that are intrinsic to medium- and high-entropy alloys are difficult to detect and quantify. Here the authors perform a diffraction data-mining analysis, revealing nanoclusters of short-range orders in a CrCoNi alloy, and their impacts on chemical homogeneity and dislocations slip.

Haw-Wen Hsiao
Rui Feng
Jian-Min Zuo
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-9
Stroboscopic operando spectroscopy of the dynamics in heterogeneous catalysis by event-averaging

To follow in situ and in real time how catalyst surfaces respond to gas composition changes is a challenge. This study reports on an eventaveraging method, based on cyclic gas pulsing and software-based image recognition, that overcomes the challenge for large photoelectron spectroscopy datasets.

Jan Knudsen
Tamires Gallo
Joachim Schnadt
ResearchOpen Access21 Oct 2021
Nature Communications

Volume: 12, P: 1-8
A plan for mental illness

The Royal Society International Seminar Consortium describes what the next decade of mental-health drug development should look like.

Thomas R. Insel
Barbara J. Sahakian
John H. Williams
Comments & Opinion14 Mar 2012
Nature

Volume: 483, P: 269
Malignant Teratoma of the Thyroid. Case Report and a Review of the Literature

D P E Kingsley
A Elton
M H Bennett
Research01 Mar 1968
British Journal of Cancer

Volume: 22, P: 7-11
Vitamin B₅ supports MYC oncogenic metabolism and tumor progression in breast cancer

In this study, Kreuzaler et al. perform zonal analysis to study metabolic heterogeneity in breast cancer and identify the metabolic dependency on pantothenic acid (vitamin B5) in areas of the tumor that show high expression levels of the oncogene MYC. Dietary restriction of vitamin B5 reverses several MYC-driven metabolic changes and hampers tumor progression.

Peter Kreuzaler
Paolo Inglese
Mariia Yuneva
ResearchOpen Access09 Nov 2023
Nature Metabolism

Volume: 5, P: 1870-1886
Observation of persistent species temperature separation in inertial confinement fusion mixtures

The influence of contaminants is one of the factors hindering self-sustained thermonuclear burn in inertial confinement fusion. Here, the authors present evidence, through simulations and experiments, that contaminants do not fully reach thermal equilibrium, and thus their amount is usually underestimated.

Brian M. Haines
R. C. Shah
D. W. Schmidt
ResearchOpen Access28 Jan 2020
Nature Communications

Volume: 11, P: 1-9
Radiation Hazards

W. J. GIBBS
J. R. MORONEY
E. W. TITTERTON
Correspondence17 Oct 1970
Nature

Volume: 228, P: 297-298
The Kea: a New Zealand Problem

A. D.
Books & Arts16 Dec 1909
Nature

Volume: 82, P: 186-187
Human and mouse essentiality screens as a resource for disease gene discovery

Discovery of causal variants for monogenic disorders has been facilitated by whole exome and genome sequencing, but does not provide a diagnosis for all patients. Here, the authors propose a Full Spectrum of Intolerance to Loss-of-Function (FUSIL) categorization that integrates gene essentiality information to aid disease gene discovery.

Pilar Cacheiro
Violeta Muñoz-Fuentes
Coleen Kane
ResearchOpen Access31 Jan 2020
Nature Communications

Volume: 11, P: 1-16
The sequence and analysis of duplication-rich human chromosome 16

Joel Martin
Cliff Han
Len A. Pennacchio
Research23 Dec 2004
Nature

Volume: 432, P: 988-994
The oldest North American pachycephalosaurid and the hidden diversity of small-bodied ornithischian dinosaurs

Fossils of small dinosaurs are less common than their large-bodied counterparts, but whether this relates to preservational biases remains unclear. Evans et al.describe a new pachycephalosaur and provide the first evidence that small-bodied dinosaur diversity is strongly underestimated.

David C. Evans
Ryan K. Schott
Michael J. Ryan
Research07 May 2013
Nature Communications

Volume: 4, P: 1-11
Magnetism and Life

D. C. SPANNER
Books & Arts01 Aug 1965
Nature

Volume: 207, P: 563-564
Bone morphogenetic protein 7 promotes resistance to immunotherapy

The mechanisms underlying resistance to immunotherapy are still poorly understood. Here, the authors show that BMP7, a molecule part of the TGF-beta superfamily, suppresses proinflammatory antitumor responses and may represent a target for overcoming resistance to PD1 inhibitors.

Maria Angelica Cortez
Fatemeh Masrorpour
James W. Welsh
ResearchOpen Access24 Sept 2020
Nature Communications

Volume: 11, P: 1-14
Seasonal Influence on Blood Pressure in Elderly Normotensive Subjects

Tomohito Hayashi
Kenji Ohshige
Osamu Tochikubo
Research01 Mar 2008
Hypertension Research

Volume: 31, P: 569-574
Simplifications and approximations in a single-gene circuit modeling

Alejandro Barton
Pablo Sesin
Luis Diambra
ResearchOpen Access31 May 2024
Scientific Reports

Volume: 14, P: 1-11
Genome-scale RNAi profiling of cell division in human tissue culture cells

Ralf Kittler
Laurence Pelletier
Frank Buchholz
Research11 Nov 2007
Nature Cell Biology

Volume: 9, P: 1401-1412
Effects of cimetidine and indomethacin on the growth of dimethylhydrazine-induced or transplanted intestinal cancers in the rat

A Caignard
M Martin
F Martin
Research01 Nov 1984
British Journal of Cancer

Volume: 50, P: 661-665
'Blue ostriches' captured

P. V. Tobias
T. A. Dowson
J. D. Lewis-Williams
Correspondence16 Jul 1992
Nature

Volume: 358, P: 185
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response

The heterogeneity of breast cancer has a major role in drug response and resistance. In this study, the authors use patient-derived tumour xenografts as a platform for drug testing and correlation with single-cell proteomic phenotypes characterized by mass cytometry.

Dimitra Georgopoulou
Maurizio Callari
Carlos Caldas
ResearchOpen Access31 Mar 2021
Nature Communications

Volume: 12, P: 1-18
History Of British Plants

C. D. PIGOTT
Books & Arts20 Jun 1970
Nature

Volume: 226, P: 1174-1175
Prefrontal neurons transmit signals to parietal neurons that reflect executive control of cognition

To examine the nature of information encoded by prefrontal output signals, the authors simultaneously recorded neuronal activity in monkey prefrontal and parietal cortices during a rule-based spatial categorization task. They found that signals reflecting rule-dependent categories were selectively transmitted from prefrontal to parietal neurons.

David A Crowe
Shikha J Goodwin
Matthew V Chafee
Research01 Sept 2013
Nature Neuroscience

Volume: 16, P: 1484-1491
Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15

Renier J. Brentjens
Jean-Baptiste Latouche
Michel Sadelain
Research10 Feb 2003
Nature Medicine

Volume: 9, P: 279-286
Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells

A J Stevenson
M S Giles
A Whitehouse
ResearchOpen Access04 Jul 2000
British Journal of Cancer

Volume: 83, P: 329-332
The feasibility of testing experimentally the dietary fat-breast cancer hypothesis

NF Boyd
M Cousins
D Tritchler
Editorial01 Dec 1990
British Journal of Cancer

Volume: 62, P: 878-881
Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

High-throughput in vitro analysis of TALE nuclease (TALEN) cleavage specificity gives insight into the mechanism of TALE binding and allows the design of TALENs with lower off-target activity.

John P Guilinger
Vikram Pattanayak
David R Liu
Research16 Feb 2014
Nature Methods

Volume: 11, P: 429-435
Chiral DNA sequences as commutable controls for clinical genomics

Any DNA sequence can be represented by a chiral partner sequence – an exact copy arranged in reverse nucleotide order. Here, the authors show that chiral DNA sequence pairs share important properties and show the utility of synthetic chiral sequences (sequins) as controls for clinical genomics.

Ira W. Deveson
Bindu Swapna Madala
Tim R. Mercer
ResearchOpen Access22 Mar 2019
Nature Communications

Volume: 10, P: 1-13
Science of Surfaces

D. D. ELEY
Books & Arts29 Dec 1972
Nature

Volume: 240, P: 573
Infrared in Space

D. K. AITKEN
Books & Arts16 Mar 1973
Nature

Volume: 242, P: 208-209
Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon

R Tikkanen
J Tiihonen
M Virkkunen
ResearchOpen Access17 Nov 2015
Translational Psychiatry

Volume: 5, P: e681
Stability of Interindividual Differences in Serotonin Function and Its Relationship to Severe Aggression and Competent Social Behavior in Rhesus Macaque Females

J. D. Higley
S. T. King, Jr.
M. Linnoila
Research01 Jan 1996
Neuropsychopharmacology

Volume: 14, P: 67-76
Photosynthetic Enzymes

D. A. WALKER
Books & Arts29 Dec 1972
Nature

Volume: 240, P: 573-574
Effects of Valproic Acid on β-adrenergic Receptors, G-proteins, and Adenylyl Cyclase in Rat C6 Glioma Cells

Guang Chen
Husseini K Manji
William Z Potter
Research01 Sept 1996
Neuropsychopharmacology

Volume: 15, P: 271-280
Association of Serotonin 5-HT_2A Receptor Binding and the T102C Polymorphism in Depressed and Healthy Caucasian Subjects

Vadim D Khait
Yung-yu Huang
J John Mann
Research13 Oct 2004
Neuropsychopharmacology

Volume: 30, P: 166-172
A Preliminary Neuroendocrine Study with Buspirone in Major Depression

Frederick G. Moeller
Joel L. Steinberg
Frederick Petty
Research01 Apr 1994
Neuropsychopharmacology

Volume: 10, P: 75-83
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Subtypes of cancer associated fibroblasts can both promote and suppress tumorigenesis. Here, the authors investigate how p53 status in pancreatic cancer cells affects their interaction with cancer associated fibroblasts, and report perlecan as a mediator of the pro-metastatic environment.

Claire Vennin
Pauline Mélénec
Paul Timpson
ResearchOpen Access12 Aug 2019
Nature Communications

Volume: 10, P: 1-22
Transformation of the intestinal epithelium by the MSI2 RNA-binding protein

In mammals there are two Musashi proteins, MSI1 and MSI2, orthologues of the Drosophila protein, with roles in asymmetric stem cell division and cell fate determination. Here the authors report new functions for MSI2 in colorectal cancer using in vitro loss of function and in vivoectopic overexpression.

Shan Wang
Ning Li
Christopher J. Lengner
Research16 Mar 2015
Nature Communications

Volume: 6, P: 1-15
Tumour-infiltrating lymphocytes bear the 75 kDa tumour necrosis factor receptor

L Trentin
R Zambello
G Semenzato
Research01 Feb 1995
British Journal of Cancer

Volume: 71, P: 240-245
Multivariate analysis of disorder in metal–organic frameworks

Structural disorder in materials is challenging to characterise. Here, the authors use multivariate analysis of atomic pair distribution functions to study structural collapse and melting of metal–organic frameworks, revealing powerful mechanistic and kinetic insight.

Adam F. Sapnik
Irene Bechis
Thomas D. Bennett
ResearchOpen Access21 Apr 2022
Nature Communications

Volume: 13, P: 1-13
Dietary patterns and cognitive function in elderly men in Finland, Italy and the Netherlands

PPCW Huijbregts
EJM Feskens
D Kromhout
Research03 Nov 1998
European Journal of Clinical Nutrition

Volume: 52, P: 826-831
Contrasting evolutionary genome dynamics between domesticated and wild yeasts

Jia-Xing Yue, Gianni Liti and colleagues use long-read sequencing to generate complete genome assemblies of 7 Saccharomyces cerevisiae and 5 Saccharomyces paradoxus strains. They use these data to define boundaries between chromosomal core and subtelomeric regions and to compare the evolutionary dynamics between these domesticated and wild yeast species.

Jia-Xing Yue
Jing Li
Gianni Liti
ResearchOpen Access17 Apr 2017
Nature Genetics

Volume: 49, P: 913-924
The distribution of iron and iron binding proteins in spleen with reference to Hodgkin's disease

K J Britten
D B Jones
D H Wright
Research01 Aug 1986
British Journal of Cancer

Volume: 54, P: 277-286
Is There a Relationship between Baseline and Treatment-Associated Changes in [³H]-IMI Platelet Binding and Clinical Response in Major Depression?

Gary D. Tollefson
John H. Heiligenstein
Charles B. Nemeroff
Research01 Jan 1996
Neuropsychopharmacology

Volume: 14, P: 47-53
Coastal vulnerability across the Pacific dominated by El Niño/Southern Oscillation

The dynamic components of coastal water level can add metres to water levels during extreme events. A data synthesis reveals that Pacific regional wave and water level fluctuations are closely related to the El Niño/Southern Oscillation.

Patrick L. Barnard
Andrew D. Short
Derek K. Heathfield
Research21 Sept 2015
Nature Geoscience

Volume: 8, P: 801-807
Seasonal Variation in Neuroendocrine and Mood Responses to IV L-Tryptophan in Depressed Patients and Healthy Subjects

Angela Cappiello
Robert T Malison
Lawrence H Price
Research01 Nov 1996
Neuropsychopharmacology

Volume: 15, P: 475-483
Studies of Catecholamine Metabolism in Schizophrenia/Psychosis-II

James W. Maas
Salvador A. Contreras
Susan E. Weintraub
Research01 Feb 1993
Neuropsychopharmacology

Volume: 8, P: 111-116
Mutations in PTF1A cause pancreatic and cerebellar agenesis

Gabrielle S Sellick
Karen T Barker
Richard S Houlston
Research14 Nov 2004
Nature Genetics

Volume: 36, P: 1301-1305
The genetics of floral development differentiating two species of Mimulus (Scrophulariaceae)

Charles B Fenster
Pamela K Diggle
Kermit Ritland
Research01 Mar 1995
Heredity

Volume: 74, P: 258-266
Serotonin 5-HT_2A Receptor Binding in Platelets from Healthy Subjects as Studied by [³H]-Lysergic Acid Diethylamide ([³H]-LSD): Intra- and Interindividual Variability

Olav Spigset
Tom Mjörndal
Research01 Apr 1997
Neuropsychopharmacology

Volume: 16, P: 285-293

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