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Showing 1–50 of 124 results

Advanced filters: Author: D Javitt Clear advanced filters

Reversal of Phencyclidine-Induced Hyperactivity by Glycine and the Glycine Uptake Inhibitor Glycyldodecylamide

Daniel C Javitt
Henry Sershen
Abel Lajtha
Research01 Sept 1997
Neuropsychopharmacology

Volume: 17, P: 202-204
Continuous Phencyclidine Treatment Induces Schizophrenia-Like Hyperreactivity of Striatal Dopamine Release

Andrea Balla
Rajeth Koneru
Daniel C Javitt
Research01 Aug 2001
Neuropsychopharmacology

Volume: 25, P: 157-164
7-Nitroindazole and Methylene Blue, Inhibitors of Neuronal Nitric Oxide Synthase and NO-Stimulated Guanylate Cyclase, Block MK-801-Elicited Behaviors in Mice

Stephen I Deutsch
Richard B Rosse
John Mastropaolo
Research01 Jul 1996
Neuropsychopharmacology

Volume: 15, P: 37-43
Glutamate receptors as therapeutic targets

D C Javitt
Research25 Oct 2004
Molecular Psychiatry

Volume: 9, P: 979
Relationship Between Glycine Transporter 1 Inhibition as Measured with Positron Emission Tomography and Changes in Cognitive Performances in Nonhuman Primates

S A Castner
N V Murthy
M Laruelle
Research03 Feb 2014
Neuropsychopharmacology

Volume: 39, P: 2742-2749
Behavioral and Neuroendocrine Effects of the Partial NMDA Agonist D-cycloserine in Healthy Subjects

BNM van Berckel
C Lipsch
RS Kahn
Research01 May 1997
Neuropsychopharmacology

Volume: 16, P: 317-324
Effects of Chronic Olanzapine and Haloperidol Differ on the Mouse N1 Auditory Evoked Potential

Christina R Maxwell
Yuling Liang
Steven J Siegel
Research21 Jan 2004
Neuropsychopharmacology

Volume: 29, P: 739-746
The Neuropsychopharmacology of Phencyclidine: From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia

J David Jentsch
Robert H Roth
Reviews01 Mar 1999
Neuropsychopharmacology

Volume: 20, P: 201-225
Non-Clozapine interventions in treatment-resistant schizophrenia: a systematic review and meta-analysis

Richard Carr
Alistair Cannon
Robert A. McCutcheon
ReviewsOpen Access03 Oct 2025
Molecular Psychiatry

P: 1-19
Glutamate Modulation of Dopamine Measured in Vivo with Positron Emission Tomography (PET) and ¹¹C-Raclopride in Normal Human Subjects

Gwenn S Smith
Ralf Schloesser
Robert Cancro
Research01 Jan 1998
Neuropsychopharmacology

Volume: 18, P: 18-25
Reduced Cortical Thickness is Associated with the Glutamatergic Regulatory Gene Risk Variant DAOA Arg30Lys in Schizophrenia

C Christoph Schultz
Igor Nenadic
Ralf G M Schlösser
Research20 Apr 2011
Neuropsychopharmacology

Volume: 36, P: 1747-1753
Quantitative Trait Loci Contributing to Phencyclidine-Induced and Amphetamine-Induced Locomotor Behavior in Inbred Mice

Robert C Alexander
Renee Wright
William Freed
Research01 Nov 1996
Neuropsychopharmacology

Volume: 15, P: 484-490
Glycine Reduces Novelty- and Methamphetamine-Induced Locomotor Activity in Neonatal Ventral Hippocampal Damaged Rats

Kozo Kato
Toshiaki Shishido
Shin-ich Niwa
Research01 Mar 2001
Neuropsychopharmacology

Volume: 24, P: 330-332
The Effects of a Sub-Anaesthetic Dose of Ketamine on Human Selective Attention

B Oranje
BNM van Berckel
MN Verbaten
Research01 Mar 2000
Neuropsychopharmacology

Volume: 22, P: 293-302
D-Cycloserine Increases Positive Symptoms in Chronic Schizophrenic Patients When Administered in Addition to Antipsychotics: A Double-Blind, Parallel, Placebo-Controlled Study

BNM van Berckel
CN Evenblij
RS Kahn
Research01 Aug 1999
Neuropsychopharmacology

Volume: 21, P: 203-210
Subchronic Phencyclidine Administration Increases Mesolimbic Dopaminergic System Responsivity and Augments Stress- and Psychostimulant-Induced Hyperlocomotion

J David Jentsch
Jane R Taylor
Robert H Roth
Research01 Aug 1998
Neuropsychopharmacology

Volume: 19, P: 105-113
Neurochemical, Electrophysiological and Pharmacological Profiles of the Selective Inhibitor of the Glycine Transporter-1 SSR504734, a Potential New Type of Antipsychotic

Ronan Depoortère
Gihad Dargazanli
Bernard Scatton
Research08 Jun 2005
Neuropsychopharmacology

Volume: 30, P: 1963-1985
NMDA Receptor Function and Human Cognition: The Effects of Ketamine in Healthy Volunteers

Anil K Malhotra
Debra A Pinals
Alan Breier
Research01 May 1996
Neuropsychopharmacology

Volume: 14, P: 301-307
Auditory dysfunction in schizophrenia: integrating clinical and basic features

Schizophrenia is characterized by various neurocognitive deficits, including impairments in auditory function. In this Review, Javitt and Sweet examine the behavioural, neurophysiological and structural evidence for auditory cortical dysfunction in this disorder and explore some of the possible underlying mechanisms.

Daniel C. Javitt
Robert A. Sweet
Reviews20 Aug 2015
Nature Reviews Neuroscience

Volume: 16, P: 535-550
Subanesthetic Doses of Ketamine Stimulate Psychosis in Schizophrenia

Adrienne C Lahti
Bettylou Koffel
Carol A Tamminga
Research01 Aug 1995
Neuropsychopharmacology

Volume: 13, P: 9-19
Cell-autonomous innate immunity by proteasome-derived defence peptides

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that could lead to biotechnology applications and therapeutic interventions.

Karin Goldberg
Arseniy Lobov
Yifat Merbl
ResearchOpen Access05 Mar 2025
Nature

Volume: 639, P: 1032-1041
The Competitive NMDA Antagonist CPP Blocks MK-801-Elicited Popping Behavior in Mice

Stephen I Deutsch
Richard B Rosse
John Mastropaolo
Research01 Oct 1996
Neuropsychopharmacology

Volume: 15, P: 329-331
Glycine Transporter Inhibitor Attenuates the Psychotomimetic Effects of Ketamine in Healthy Males: Preliminary Evidence

Deepak Cyril D'Souza
Nagendra Singh
Jacques Schipper
Research23 Nov 2011
Neuropsychopharmacology

Volume: 37, P: 1036-1046
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC

Merbl and colleagues demonstrate that high expression of the proteasome regulator PSME4 is associated with immune-cold lung tumors and reduced antitumor immune responses, by functioning to modulate the protein degradome and antigen diversity.

Aaron Javitt
Merav D. Shmueli
Yifat Merbl
Research22 May 2023
Nature Cancer

Volume: 4, P: 629-647
Differential and Region-Specific Activation of Mitogen-Activated Protein Kinases Following Chronic Administration of Phencyclidine in Rat Brain

Svetlana V Kyosseva
S Michael Owens
Craig N Karson
Research01 Mar 2001
Neuropsychopharmacology

Volume: 24, P: 267-277
Synapse-Associated Protein 90/Postsynaptic Density-95-Associated Protein (SAPAP) is Expressed Differentially in Phencyclidine-Treated Rats and is Increased in the Nucleus Accumbens of Patients with Schizophrenia

Yasuo Kajimoto
Osamu Shirakawa
Kiyoshi Maeda
Research28 Apr 2003
Neuropsychopharmacology

Volume: 28, P: 1831-1839
Repeated Phencyclidine Treatment Induces Negative Symptom-like Behavior in Forced Swimming Test in Mice: Imbalance of Prefrontal Serotonergic and Dopaminergic Functions

Yukihiro Noda
Hiroyuki Kamei
Toshitaka Nabeshima
Research01 Oct 2000
Neuropsychopharmacology

Volume: 23, P: 375-387
Abnormal Kainate Receptor Expression in Prefrontal Cortex in Schizophrenia

James H Meador-Woodruff
Kenneth L Davis
Vahram Haroutunian
Research09 Aug 2000
Neuropsychopharmacology

Volume: 24, P: 545-552
Letter

M Hingorani
D Mooney
A Singh
Correspondence01 May 1995
Eye

Volume: 9, P: 392-393
New Insights into the Biology of Schizophrenia through the Mechanism of Action of Clozapine

Nicoletta Brunello
Claudio Masotto
Giorgio Racagni
Reviews01 Nov 1995
Neuropsychopharmacology

Volume: 13, P: 177-213
Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors

A computational pipeline identifies tumor antigen post-translational modifications guiding immune responses.

Assaf Kacen
Aaron Javitt
Yifat Merbl
Research06 Oct 2022
Nature Biotechnology

Volume: 41, P: 239-251
Imaging glutamate in schizophrenia: review of findings and implications for drug discovery

E M P Poels
L S Kegeles
R R Girgis
Reviews29 Oct 2013
Molecular Psychiatry

Volume: 19, P: 20-29
Neuropharmacological Profile of a Novel Potential Atypical Antipsychotic Drug Y-931 (8-fluoro-12-(4-methylpiperazin-1-yl)- 6H-[1]benzothieno[2,3-b][1,5] benzodiazepine maleate)

Toshihiko Morimoto
Kenji Hashimoto
Keiji Yamagami
Research27 Aug 2001
Neuropsychopharmacology

Volume: 26, P: 456-467
Effects of the Nitric Oxide Synthase Inhibitor L-NAME on Recognition and Spatial Memory Deficits Produced by Different NMDA Receptor Antagonists in the Rat

Antonios Boultadakis
Nikolaos Pitsikas
Research21 Jul 2010
Neuropsychopharmacology

Volume: 35, P: 2357-2366
Dopamine is not Required for the Hyperlocomotor Response to NMDA Receptor Antagonists

Elena H Chartoff
Carrie L Heusner
Richard D Palmiter
Research26 Jan 2005
Neuropsychopharmacology

Volume: 30, P: 1324-1333
NMDA-Sensitive Glutamate Antagonism: A Human Model for Psychosis

Adrienne C Lahti
Henry H Holcomb
Carol A Tamminga
Research01 Dec 1999
Neuropsychopharmacology

Volume: 21, P: S158-S169
Feasibility, Safety, and Efficacy of the Combination of D-Serine and Computerized Cognitive Retraining in Schizophrenia: An International Collaborative Pilot Study

Deepak C D'Souza
Rajiv Radhakrishnan
Chittaranjan Andrade
Research24 Oct 2012
Neuropsychopharmacology

Volume: 38, P: 492-503
SSR180711, a Novel Selective α7 Nicotinic Receptor Partial Agonist: (II) Efficacy in Experimental Models Predictive of Activity Against Cognitive Symptoms of Schizophrenia

Philippe Pichat
Olivier E Bergis
Bernard Scatton
Research23 Aug 2006
Neuropsychopharmacology

Volume: 32, P: 17-34
Effects of Continuous D-Amphetamine and Phencyclidine Administration on Social Behaviour, Stereotyped Behaviour, and Locomotor Activity in Rats

Frank Sams-Dodd
Research01 Jul 1998
Neuropsychopharmacology

Volume: 19, P: 18-25
Letter

D K Newman
S Anwar
K Jordan
Correspondence01 Nov 2000
Eye

Volume: 14, P: 926-927
Retinopathy of prematurity in practice. I: screening for threshold disease

R Brennan
L Gnanaraj
D G Cottrell
Research14 Mar 2003
Eye

Volume: 17, P: 183-188
Serum Bile Acids in Newborns and Children

L Barbara
R Lazzari
E Roda
Research01 Nov 1980
Pediatric Research

Volume: 14, P: 1222-1225
Letter

C D Morsman
Correspondence01 May 1995
Eye

Volume: 9, P: 392
Topical anaesthesia for phacoemulsification surgery

I G M Duguid
C M P Claoué
A D McG Steele
Research01 Jul 1995
Eye

Volume: 9, P: 456-459
Biliary Bile Acid Composition of the Human Fetus in Early Gestation

C Colombo
G Zuliani
K D R Setchel
Research01 Feb 1987
Pediatric Research

Volume: 21, P: 197-200
Excimer laser sclerostomy: The in vitro development of a modified open mask delivery system

B D S Allan
P P Van Saarloos
I J Constable
Research01 Jan 1993
Eye

Volume: 7, P: 47-52
Phencyclidine Impairs Latent Learning in Mice: Interaction between Glutamatergic Systems and Sigma₁ Receptors

Akihiro Noda
Yukihiro Noda
Toshitaka Nabeshima
Research01 Apr 2001
Neuropsychopharmacology

Volume: 24, P: 451-460
Comparison between an ophthalmic optician and an ophthalmologist in screening for diabetic retinopathy

C J Hammond
J Shackleton
J Wade
Research01 Jan 1996
Eye

Volume: 10, P: 107-112
Therapeutic Implications of the Hyperglutamatergic Effects of NMDA Antagonists

John H Krystal
Aysenil Belger
Bita Moghaddam
Research01 Dec 1999
Neuropsychopharmacology

Volume: 21, P: S143-S157
Animal Models of Negative Symptoms: M100907 Antagonizes PCP-Induced Immobility in a Forced Swim Test in Mice

Roy Corbett
Lily Zhou
Cesare Mondadori
Research01 Dec 1999
Neuropsychopharmacology

Volume: 21, P: S211-S218

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