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Showing 1–50 of 150 results

Advanced filters: Author: D Mair Clear advanced filters

Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes

PROTACs induce degradation by bridging a target protein and E3 ubiquitin ligase. Here, authors show that protein interface frustration correlates with cooperativity, offering a structural metric to prioritize PROTAC candidates prior to synthesis.

Ning Ma
Supriyo Bhattacharya
Nagarajan Vaidehi
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-12
Fracture Criterion for Cast Iron

H. LL. D. PUGH
Research08 Jun 1968
Nature

Volume: 218, P: 985
A New Series of Isoprenoid Isoalkanes in Crude Oils and Cretaceous Bituminous Shales

K. E. H. GÖHRING
P. A. SCHENCK
E. D. ENGELHARDT
Research15 Jul 1967
Nature

Volume: 215, P: 503-505
Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

C. C. F. BLAKE
D. F. KOENIG
V. R. SARMA
Research22 May 1965
Nature

Volume: 206, P: 757-761
Tertiary Structure of Ribonuclease

G. KARTHA
J. BELLO
D. HARKER
Research01 Mar 1967
Nature

Volume: 213, P: 862-865
ADTnorm: robust integration of single-cell protein measurement across CITE-seq datasets

Here the authors present a computational method that expands the potential of multimodal single-cell analyses by delivering an accurate, fast, and user-friendly approach for normalizing and comparing surface protein expression across large and heterogeneous datasets.

Ye Zheng
Daniel P. Caron
Raphael Gottardo
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
The Role of Distortion in the Lysozyme-catalysed Hydrolysis of Glucosides

B. D. SYKES
D. DOLPHIN
Research08 Oct 1971
Nature

Volume: 233, P: 421-422
Three-dimensional Structure of Tosyl-elastase

D. M. SHOTTON
H. C. WATSON
Research28 Feb 1970
Nature

Volume: 225, P: 811-816
A Second Right-handed Helical Structure with the Parameters of the Pauling–Corey α-helix

GEORGE NÉMETHY
D. C. PHILLIPS
HAROLD A. SCHERAGA
Research22 Apr 1967
Nature

Volume: 214, P: 363-365
Exploiting long read sequencing to detect azole fungicide resistance mutations in Pyrenophora teres using unique molecular identifiers

Katherine G. Zulak
Lina Farfan-Caceres
Francisco J. Lopez-Ruiz
ResearchOpen Access15 Mar 2024
Scientific Reports

Volume: 14, P: 1-13
Three-dimensional Structure of Tosyl-α-chymotrypsin

B. W. MATTHEWS
P. B. SIGLER
D. M. BLOW
Research13 May 1967
Nature

Volume: 214, P: 652-656
Magnetic and Chemical Investigations of Iron in Tektites

A. N. THORPE
F. E. SENFTLE
F. CUTTITTA
Research02 Mar 1963
Nature

Volume: 197, P: 836-840
The Continuity of Existence

D. B. MAIR
Research05 Feb 1927
Nature

Volume: 119, P: 199
Prediction of chain turns in globular proteins on a hydrophobic basis

George D. Rose
Research13 Apr 1978
Nature

Volume: 272, P: 586-590
Crystallographic study of the interaction of urea with lysozyme

High-quality crystals suitable for an X-ray crystal-lographic study have been obtained for urea-denatured lysozyme

K. W. Snape
Robert Tjian
D. E. Koshland jun.
Research26 Jul 1974
Nature

Volume: 250, P: 295-298
Organic Geochemistry

G. D. HOBSON
Research01 Jan 1965
Nature

Volume: 205, P: 16-18
Spectroscopic Evidence of Chemical Interactions at the Gold Film–Silica Substrate Interface

C. R. GUERRA
T. W. HEALY
D. W. FUERSTENAU
Research01 Jul 1965
Nature

Volume: 207, P: 518-520
The Crystal as Diffraction Grating

D. B. MAIR
Research30 Jan 1926
Nature

Volume: 117, P: 157-158
Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex

Ubinuclein-1 (UBN1) is a subunit of the HIRA histone chaperone complex that deposits histone H3.3 into chromatin. Here the authors use structural and biochemical studies to show that a conserved domain in UBN1 mediates H3.3-specific binding by the HIRA complex.

M Daniel Ricketts
Brian Frederick
Ronen Marmorstein
ResearchOpen Access10 Jul 2015
Nature Communications

Volume: 6, P: 1-11
Measurement of Thermal Accommodation of Gases on Heated Solids

L. G. CARPENTER
D. E. HUMPHRIES
W. N. MAIR
Research13 Jul 1963
Nature

Volume: 199, P: 164-165
Cell-intrinsic metabolic phenotypes identified in patients with glioblastoma, using mass spectrometry imaging of ¹³C-labelled glucose metabolism

Tsyben et al. study the spatial distribution of labelled metabolites in glioblastoma samples from patients infused with ¹³C-glucose, using mass spectrometry imaging.

Anastasia Tsyben
Andreas Dannhorn
Kevin M. Brindle
ResearchOpen Access19 May 2025
Nature Metabolism

Volume: 7, P: 928-939
Stereochemistry of Copper in Bis(N-t-butylsalicylaldiminato)copper(II)

T. P. CHEESEMAN
D. HALL
T. N. WATERS
Research01 Jan 1965
Nature

Volume: 205, P: 494-495
2.3- and 2.5-Dihydrothiophenes

S. F. BIRCH
D. T. MCALLAN
Research03 Jun 1950
Nature

Volume: 165, P: 899
Trimerization of Nickel-(II) Acetylacetonate in Solution

D. P. GRADDON
E. C. WATTON
Research03 Jun 1961
Nature

Volume: 190, P: 906-907
Three-dimensional Fourier Synthesis of Tosyl-elastase at 3.5 Å Resolution

H. C. WATSON
D. M. SHOTTON
HILARY MUIRHEAD
Research28 Feb 1970
Nature

Volume: 225, P: 806-811
Persistence of Sudanophilic Lipid in Sections of Mummified Tissue

A. T. SANDISON
Research17 Jan 1959
Nature

Volume: 183, P: 196-197
X-ray structure of an anti-fungal chitosanase from streptomyces N174

Edward M. Marcotte
Arthur F. Monzingo
Jon D. Robertas
Research01 Feb 1996
Nature Structural Biology

Volume: 3, P: 155-162
“Let us talk”: incorporating the Coordinated Management of Meaning’s communication perspective as part of public diplomacy efforts between government, the private sector, and the foreign public

Blerim Limani
Emira Limani
ResearchOpen Access25 Aug 2022
Humanities and Social Sciences Communications

Volume: 9, P: 1-7
X-ray crystallography of the binding of the bacterial cell wall trisaccharide NAM-NAG-NAM to lysozyme

Judith A. Kelly
Anita R. Sielecki
David C. Phillips
Research20 Dec 1979
Nature

Volume: 282, P: 875-878
Two unlinked loci controlling the sex of blue tilapia (Oreochromis aureus)

B-Y Lee
G Hulata
T D Kocher
Research21 Apr 2004
Heredity

Volume: 92, P: 543-549
Maintenance of appropriate size scaling of the C. elegans pharynx by YAP-1

Imbalance in the growth rate of two organs can perturb their appropriate scaling. Here, Stojanovski et al., identify a mechanism involving the mechanotransducer YAP-1 which ensures proper proportions of the pharynx and the body length of C. elegans.

Klement Stojanovski
Ioana Gheorghe
Benjamin D. Towbin
ResearchOpen Access20 Nov 2023
Nature Communications

Volume: 14, P: 1-13
H₂S incorporation in coal precursors: origins of organic sulphur in coal

D. J. Casagrande
G. Idowu
D. Schlenz
Research06 Dec 1979
Nature

Volume: 282, P: 599-600
Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans

Precursor mRNA splicing homeostasis is a biomarker and predictor of life expectancy in Caenorhabditis elegans and defects in global pre-mRNA splicing associated with age are reduced by dietary restriction via splicing factor 1.

Caroline Heintz
Thomas K. Doktor
William B. Mair
Research05 Dec 2016
Nature

Volume: 541, P: 102-106
An investment strategy to address biodiversity loss from agricultural expansion

The 2016 peace agreement in Colombia led to agricultural expansion to the detriment of biodiversity. Using Colombia as a case study, this work shows how to maximize the biodiversity benefits from limited conservation funding while landowners maintain economic returns equivalent to those from agriculture.

Camila Guerrero-Pineda
Gwenllian D. Iacona
Leah R. Gerber
Research14 Apr 2022
Nature Sustainability

Volume: 5, P: 610-618
Author Correction: RANO criteria for response assessment of brain metastases based on amino acid PET imaging

Nathalie L. Albert
Norbert Galldiks
Matthias Preusser
Amendments and Corrections09 Jun 2025
Nature Medicine

Volume: 31, P: 2816
Key residues involved in calcium-binding motifs in EGF-like domains

P. A. Handford
M. Mayhew
G. G. Brownlee
Research09 May 1991
Nature

Volume: 351, P: 164-167
A metric for spatially explicit contributions to science-based species targets

The species threat abatement and restoration (STAR) metric quantifies the contributions that abating threats and restoring habitats offer towards reducing species’ extinction risk in specific places.

Louise Mair
Leon A. Bennun
Philip J. K. McGowan
Research08 Apr 2021
Nature Ecology & Evolution

Volume: 5, P: 836-844
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level

Medulloblastomas (MBs) are highly heterogeneous paediatric brain tumours that remain challenging to treat. Here, the authors integrate proteomics, epigenomics, transcriptomics and post-translational modification analyses to find molecular subgroups and potential therapeutic targets in MB tumours.

Shweta Godbole
Hannah Voß
Julia E. Neumann
ResearchOpen Access24 Jul 2024
Nature Communications

Volume: 15, P: 1-24
Intercellular adhesion molecule-1 is an endothelial cell adhesion receptor for Plasmodium falciparum

A. R. Berendt
D. L. Simmons
K. Marsh
Research07 Sept 1989
Nature

Volume: 341, P: 57-59
A magnetotelluric sounding across Vancouver Island detects the subducting Juan de Fuca plate

R. D. Kurtz
J. M. DeLaurier
J. C. Gupta
Research05 Jun 1986
Nature

Volume: 321, P: 596-599
Primary structure of dystrophin-related protein

J. M. Tinsley
D. J. Blake
K. E. Davies
Research10 Dec 1992
Nature

Volume: 360, P: 591-593
Antimicrobial resistant enteric bacteria are widely distributed amongst people, animals and the environment in Tanzania

Spread of antimicrobial-resistant (AR) bacteria is a global concern, but contributing factors remain unclear. Here, authors analyze distribution of AR bacteria in households from three ethnic groups in Tanzania and find that livelihood factors are more strongly associated with AR prevalence than antibiotic use.

Murugan Subbiah
Mark A. Caudell
Douglas R. Call
ResearchOpen Access13 Jan 2020
Nature Communications

Volume: 11, P: 1-12
Seaward extension of the East African Rift

D. Mougenot
M. Recq
C. Lepvrier
Research05 Jun 1986
Nature

Volume: 321, P: 599-603
Hippocampal abnormalities in amnesic patients revealed by high-resolution magnetic resonance imaging

G. A. Press
D. G. Amaral
L. R. Squire
Research07 Sept 1989
Nature

Volume: 341, P: 54-57
Chromosomal Abnormalities resulting from Ethidium Bromide Treatment

VICTOR D. VACQUIER
JEAN BRACHET
Research12 Apr 1969
Nature

Volume: 222, P: 193-195
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO₂

Carbon-labelled α-amino acids are valuable compounds in drug development and nuclear medicine, but are difficult and time consuming to prepare. Now, an aldehyde-catalysed method has been developed for the direct C1-labelling of α-amino acids using *CO₂ (* = 14, 13, 11), providing access to many proteinogenic and non-natural labelled α-amino acids.

Odey Bsharat
Michael G. J. Doyle
Rylan J. Lundgren
Research07 Nov 2022
Nature Chemistry

Volume: 14, P: 1367-1374
Crustal structure of the northern Alpha Ridge beneath the Arctic Ocean

D. A. Forsyth
I. Asudeh
H. R. Jackson
Research24 Jul 1986
Nature

Volume: 322, P: 349-352
Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids

Papsdorf et al. show that mono-unsaturated fatty acids extend lifespan of C. elegans through induction of peroxisomes and lipid droplets in fat tissues and of a lipid signature predictive of decreased lipid oxidation.

Katharina Papsdorf
Jason W. Miklas
Anne Brunet
ResearchOpen Access01 May 2023
Nature Cell Biology

Volume: 25, P: 672-684
Genomic epidemiology reveals multiple introductions of SARS-CoV-2 from mainland Europe into Scotland

Genomic epidemiology reveals multiple travel-related introductions of SARS-CoV-2 from mainland Europe into Scotland during the first wave of COVID-19.

Ana da Silva Filipe
James G. Shepherd
Emma C. Thomson
Research21 Dec 2020
Nature Microbiology

Volume: 6, P: 112-122
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13

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