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Showing 151–200 of 364 results

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Second malignancy in patients with Hodgkin's disease treated at the Royal Marsden Hospital

AJ Swerdlow
JA Barber
RZ Omar
Research01 Jan 1997
British Journal of Cancer

Volume: 75, P: 116-123
The Beaker phenomenon and the genomic transformation of northwest Europe

Genome-wide data from 400 individuals indicate that the initial spread of the Beaker archaeological complex between Iberia and central Europe was propelled by cultural diffusion, but that its spread into Britain involved a large-scale migration that permanently replaced about ninety per cent of the ancestry in the previously resident population.

Iñigo Olalde
Selina Brace
David Reich
Research21 Feb 2018
Nature

Volume: 555, P: 190-196
The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome

Young-Ki Paik
Seul-Ki Jeong
William S. Hancock
Correspondence07 Mar 2012
Nature Biotechnology

Volume: 30, P: 221-223
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen

C. K. Stover
X. Q. Pham
M. V. Olson
Research31 Aug 2000
Nature

Volume: 406, P: 959-964
Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity

Thomas Grewal
Rachael Evans
Carlos Enrich
Research06 Jun 2005
Oncogene

Volume: 24, P: 5809-5820
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Alexander S. Hatoum
Sarah M. C. Colbert
Arpana Agrawal
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 210-223
ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1

Lu and colleagues report that ASPP2 induces mesenchymal–epithelial transition and inhibits cancer cell invasion and metastasis by preventing the β-catenin-mediated upregulation of ZEB1.

Yihua Wang
Fangfang Bu
Xin Lu
Research26 Oct 2014
Nature Cell Biology

Volume: 16, P: 1092-1104
(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2

Rapid reversible inhibitors of the oxygenation activity of COX-2, including ibuprofen and naproxen, selectively inhibit the enzyme with endocannabinoid 2-AG substrates but not with arachidonic acid, and this substrate-selective inhibition may be important for the analgesic activity of the drugs.

Kelsey C Duggan
Daniel J Hermanson
Lawrence J Marnett
Research25 Sept 2011
Nature Chemical Biology

Volume: 7, P: 803-809
A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses

Lymphocytes integrate multiple input signals to regulate the extent of their proliferative response. Hodgkin and colleagues demonstrate that the proto-oncoprotein Myc is a cell-intrinsic division timer.

Susanne Heinzel
Tran Binh Giang
Philip D Hodgkin
Research07 Nov 2016
Nature Immunology

Volume: 18, P: 96-103
Changes in microbiome composition during ontogeny and dispersal of the coral boring sponge Thoosa mismalolli

Eric Bautista-Guerrero
José Luis Carballo
Adrián González-Castillo
ResearchOpen Access18 Jan 2025
Scientific Reports

Volume: 15, P: 1-18
Apparent competition drives community-wide parasitism rates and changes in host abundance across ecosystem boundaries

Species sharing a common enemy such as a parasitoid or predator can indirectly affect one another. Here, Frost et al. use quantitative food-web data from communities of caterpillar hosts to show experimentally that apparent competition is important in predicting food-web structure across habitats.

Carol M. Frost
Guadalupe Peralta
Jason M. Tylianakis
ResearchOpen Access31 Aug 2016
Nature Communications

Volume: 7, P: 1-12
Autoregulation of cerebral blood flow in patients with orthostatic hypotension after spinal cord injury

F Gonzalez
J Y Chang
R E Kelley
Research01 Jan 1991
Spinal Cord

Volume: 29, P: 1-7
Crystal structure of RhoA–GDP and its functional implications

RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 Å resolution crystal structure of the human RhoA–GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.

Yunyi Wei
Yan Zhang
Zygmunt S. Derewenda
Correspondence01 Sept 1997
Nature Structural Biology

Volume: 4, P: 699-703
The Annular Eclipse of April 8

A. C. D. CROMMELIN
News14 Apr 1921
Nature

Volume: 107, P: 211-212
A structural model of a Ras–Raf signalosome

A structural model of a K-Ras nanocluster that promotes the stability and accessibility of active K-Ras and creates composite interfaces that facilitate Raf binding provides a framework to unravel MAPK signaling.

Venkatesh P. Mysore
Zhi-Wei Zhou
David E. Shaw
Research08 Oct 2021
Nature Structural & Molecular Biology

Volume: 28, P: 847-857
Unexpected mortality from the use of E. coli L-asparaginase during remission induction therapy for childhood acute lymphoblastic leukemia: a report from the Taiwan Pediatric Oncology Group

D-C Liang
I-J Hung
K-S Lin
Research05 Feb 1999
Leukemia

Volume: 13, P: 155-160
DNA repeat length in chromatin from murine bone marrow and L1210 leukaemia cells

S W Dean
K D Tew
P S Schein
Research01 Sept 1985
British Journal of Cancer

Volume: 52, P: 377-382
Dr. E. Leonard Gill

D. M. S. WATSON
Comments & Opinion08 Sept 1956
Nature

Volume: 178, P: 520
Qualitative insights into a scholarship scheme designed to optimise test scores and expedite SDG-4 actualisation in Nigeria

Chris Ifediora
Karen Trimmer
Etomike Obianyo
ResearchOpen Access25 Oct 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-15
Plight of UK science

D. A. W. GRANT
Correspondence27 Aug 1987
Nature

Volume: 328, P: 754
Prof. S. W. Burnham

A. C. D. C.
Comments & Opinion14 Apr 1921
Nature

Volume: 107, P: 212-213
Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations

Genomic prediction of phenotype may be improved by using DNA mutations with functional, evolutionary, and pleiotropic consequences. Here the authors describe a method for genome-wide fine-mapping of QTLs and develop a genotyping array for improved prediction of genetic values for cattle traits.

Ruidong Xiang
Iona M. MacLeod
Michael E. Goddard
ResearchOpen Access08 Feb 2021
Nature Communications

Volume: 12, P: 1-13
The Biologic Perturbations of Persistent Embryonic Mumps Virus Infection

Joseph W St Geme Jr.
Catherine W C Davis
Miriam A Arce
Research01 Jun 1973
Pediatric Research

Volume: 7, P: 541-552
Inbreeding depression under a competitive regime in Mimulus guttatus: consequences for potential male and female function

David E Carr
Michele R Dudash
Research01 Nov 1995
Heredity

Volume: 75, P: 437-445
Hydrogel particles improve detection of SARS-CoV-2 RNA from multiple sample types

R. A. Barclay
I. Akhrymuk
B. Lepene
ResearchOpen Access30 Dec 2020
Scientific Reports

Volume: 10, P: 1-11
Delivery of therapeutic agents by nanoparticles made of grapefruit-derived lipids

Nanoparticles released from living cells can be used as drug delivery vehicles, but scaling up their production is challenging. Here, Wang and colleagues create nanoparticles from natural lipids contained in grapefruit juice that can encapsulate various types of therapeutics and deliver them to cells in vitro and in vivo.

Qilong Wang
Xiaoying Zhuang
Huang-Ge Zhang
Research21 May 2013
Nature Communications

Volume: 4, P: 1-13
Minimal residual disease after intensive induction therapy in childhood acute lymphoblastic leukemia predicts outcome

B Gruhn
S Hongeng
GR Kitchingman
Research29 May 1998
Leukemia

Volume: 12, P: 675-681
Investigating the origin and authenticity of Victoria Cross medals using X-ray fluorescence spectrometry

Andrew Marriott
James G. D. Prendergast
ResearchOpen Access19 Nov 2020
Scientific Reports

Volume: 10, P: 1-13
Genome-wide association study identifies novel breast cancer susceptibility loci

Previous work has identified several genes where mutations lead to breast cancer, but other genetic and environmental factors must still be accounted for. A large study of genetic association with breast cancer points to four novel genes and many more genetic markers that should be pursued for their link to cancer susceptibility.

Douglas F. Easton
Karen A. Pooley
Bruce A. J. Ponder
Research28 Jun 2007
Nature

Volume: 447, P: 1087-1093
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Around 10% of high-grade serous ovarian carcinomas (HGSOC) harbor BRCA1 promoter methylation, but it is uncertain how it predicts response to PARP inhibition. Here, the authors show that homozygous BRCA1 methylation predicts response to rucaparib while heterozygous methylation of BRCA1 predicts resistance in HGSOC.

Olga Kondrashova
Monique Topp
Clare L. Scott
ResearchOpen Access28 Sept 2018
Nature Communications

Volume: 9, P: 1-16
Observation of an exotic narrow doubly charmed tetraquark

The LHCb Collaboration reports the observation of an exotic, narrow, tetraquark state that contains two charm quarks, an up antiquark and a down antiquark.

R. Aaij
A. S. W. Abdelmotteleb
G. Zunica
ResearchOpen Access16 Jun 2022
Nature Physics

Volume: 18, P: 751-754
H₃ Receptor Antagonism Enhances NCAM PSA-Mediated Plasticity and Improves Memory Consolidation in Odor Discrimination and Delayed Match-to-Position Paradigms

Andrew G Foley
Alison Prendergast
Ciaran M Regan
Research05 Aug 2009
Neuropsychopharmacology

Volume: 34, P: 2585-2600
Bone marrow transplantation for therapy-induced acute myeloid leukemia in children with previous lymphoid malignancies

GA Hale
HE Heslop
RA Krance
Research30 Sept 1999
Bone Marrow Transplantation

Volume: 24, P: 735-739
Evaluation of a monoclonal antibody to ras peptide, RAP-5, claimed to bind preferentially to cells of infiltrating carcinomas

A Robinson
A R Williams
A H Wyllie
Research01 Dec 1986
British Journal of Cancer

Volume: 54, P: 877-883
Detecting adaptive evolution based on association with ecological gradients: Orientation matters!

E Frichot
S D Schoville
O François
Research18 Feb 2015
Heredity

Volume: 115, P: 22-28
An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule

Ersilia Nigro
Irene Colavita
Antonello Pessi
ResearchOpen Access21 Dec 2015
Scientific Reports

Volume: 5, P: 1-11
Accelerating the search for the missing proteins in the human proteome

The Human Proteome Project aims to catalogue the ∼20,000 proteins encoded by the human genome. In this review, Bakeret al. focus on the missing proteins, proteins that lack high stringency proteomic evidence, and launch MissingProteinPedia, a database aimed at accelerating the search for missing proteins.

Mark S. Baker
Seong Beom Ahn
Shoba Ranganathan
ReviewsOpen Access24 Jan 2017
Nature Communications

Volume: 8, P: 1-13
Discursive analysis of rejection voices against brand social responsibility initiatives in Indonesia

Bambang Sukma Wijaya
ResearchOpen Access17 Jan 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-11
On-demand manufacturing of clinical-quality biopharmaceuticals

A benchtop system for protein synthesis achieves purity and potency comparable to those of marketed drugs.

Laura E Crowell
Amos E Lu
J Christopher Love
Research01 Oct 2018
Nature Biotechnology

Volume: 36, P: 988-995
Genetic insights into smoking behaviours in 10,558 men of African ancestry from continental Africa and the UK

Noemi-Nicole Piga
Palwende Romuald Boua
Chiara Batini
ResearchOpen Access05 Nov 2022
Scientific Reports

Volume: 12, P: 1-11
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Christopher Amos and colleagues perform genome-wide association analysis for lung cancer using cohorts genotyped on the OncoArray and combing these with existing data. They identify 18 loci, 10 of which are new, finding heterogeneity across the different lung cancer subtypes, and explore candidate genes through eQTL analysis in lung tissue.

James D McKay
Rayjean J Hung
Christopher I Amos
Research12 Jun 2017
Nature Genetics

Volume: 49, P: 1126-1132
Post-traumatic syringomyelia

J D Vernon
J R Silver
A Ohry
Research01 Dec 1982
Spinal Cord

Volume: 20, P: 339-364
Evidence of sympathetic fibers in the male rat pelvic nerve by Gross anatomy, retrograde labeling and high resolution Autoradiographic study

F Giuliano
P Facchinetti
O Rampin
Research01 Dec 1997
International Journal of Impotence Research

Volume: 9, P: 179-185
Quantification of tumor cell invasion using confocal laser scan microscopy

Matthias P. Schönermark
Oliver Bock
Thomas Lenarz
Advertorial01 Oct 1997
Nature Medicine

Volume: 3, P: 1167-1171
The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells

Mark D Pegram
Richard S Finn
Dennis J Slamon
Research31 Jul 1997
Oncogene

Volume: 15, P: 537-547
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

Mathias Gorski
Peter J. van der Most
Christian Fuchsberger
ResearchOpen Access28 Apr 2017
Scientific Reports

Volume: 7, P: 1-11
Low slip rates and long-term preservation of geomorphic features in Central Asia

Ralf Hetzel
Samuel Niedermann
Manfred R. Strecker
Research23 May 2002
Nature

Volume: 417, P: 428-432
Addendum: Test of lepton universality in beauty-quark decays

R. Aaij
C. Abellán Beteta
G. Zunica
Amendments and CorrectionsOpen Access10 Aug 2023
Nature Physics

Volume: 19, P: 1517
Complications and costs of management of acute spinal cord injury

C H Tator
E G Duncan
D F Andrews
Research01 Nov 1993
Spinal Cord

Volume: 31, P: 700-714
The role of vitamin D receptor gene polymorphisms in the susceptibility to prostate cancer of a southern European population

R. Medeiros
A. Morais
C. Lopes
Research01 Aug 2002
Journal of Human Genetics

Volume: 47, P: 413-418

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