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Showing 1–50 of 626 results

Advanced filters: Author: D Witte Clear advanced filters

Sensitive near point-of-care detection of asymptomatic and submicroscopic Plasmodium falciparum infections in African endemic countries

Limited diagnostic capacity for asymptomatic individuals hinders malaria elimination efforts in Africa. Here, the authors present a near point-of-care method based on colorimetric LAMP detection that outperforms expert microscopy and commercial rapid diagnostic tests for Plasmodium detection in asymptomatic and submicroscopic individuals.

Dimbintsoa Rakotomalala Robinson
Ivana Pennisi
Asadu Sserwanga
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-13
Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health

This genomic study of magnetic resonance imaging-based brain age in 56,348 people identifies 59 genetic loci, links brain aging to mental and physical health, and suggests high blood pressure and type 2 diabetes as causal factors of brain aging.

Philippe Jawinski
Helena Forstbach
Sebastian Markett
ResearchOpen Access03 Oct 2025
Nature Aging

P: 1-18
The effect of funding for disadvantaged students on academic underachievement

Oleg Badunenko
Deni Mazrekaj
Kristof De Witte
ResearchOpen Access25 Aug 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-9
A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia

L. C. Chan
K. K. Karhi
L. M. Wiedemann
Research18 Feb 1987
Nature

Volume: 325, P: 635-637
T cell antigen discovery via signaling and antigen-presenting bifunctional receptors

Engineered, bifunctional receptors present antigens and initiate signaling in response to binding to the cognate T cell receptor. Libraries built with SABRs can screen thousands of epitopes for the discovery of T cell target antigens.

Alok V. Joglekar
Michael T. Leonard
David Baltimore
Research28 Jan 2019
Nature Methods

Volume: 16, P: 191-198
Data-driven inference of Boolean networks from transcriptomes to predict cellular differentiation and reprogramming

Stéphanie Chevalier
Julia Becker
Loïc Paulevé
ResearchOpen Access26 Sept 2025
npj Systems Biology and Applications

Volume: 11, P: 1-16
A New Heterologous Radiation Chimæra

D. W. VAN BEKKUM
Research27 Jun 1964
Nature

Volume: 202, P: 1311-1312
The Hardy–Zuckerman 2-FeSV, a new feline retrovirus with oncogene homology to Abelson-MuLV

P. Besmer
W. D. Hardy Jr
H. W. Snyder Jr
Research30 Jun 1983
Nature

Volume: 303, P: 825-828
Characterization and molecular cloning of a bovine lentivirus related to human immunodeficiency virus

Matthew A. Gonda
Michael J. Braun
Martin J. Van Der Maaten
Research26 Nov 1987
Nature

Volume: 330, P: 388-391
A foundation model to predict and capture human cognition

A computational model called Centaur, developed by fine-tuning a language model on a huge dataset called Psych-101, can predict and simulate human nature in experiments expressible in natural language, even in previously unseen situations.

Marcel Binz
Elif Akata
Eric Schulz
ResearchOpen Access02 Jul 2025
Nature

Volume: 644, P: 1002-1009
A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia

E. Fainstein
C. Marcelle
C. M. Croce
Research26 Nov 1987
Nature

Volume: 330, P: 386-388
Mechanism for Vapour Explosions

D. J. BUCHANAN
T. A. DULLFORCE
Research07 Sept 1973
Nature

Volume: 245, P: 32-34
Novel chimaeric protein expressed in Philadelphia positive acute lymphoblastic leukaemia

Lesley C. Walker
Trivadi S. Ganesan
Bryan D. Young
Research29 Oct 1987
Nature

Volume: 329, P: 851-853
Dispersion of α-like globin genes of the mouse to three different chromosomes

Aya Leder
David Swan
Philip Leder
Research17 Sept 1981
Nature

Volume: 293, P: 196-200
The ecological and genomic basis of explosive adaptive radiation

Analyses of the genomes of cichlid species reveal that the combination of ecological opportunity, sexual selection and exceptional genomic potential is the key to understanding explosive adaptive radiation in cichlids.

Matthew D. McGee
Samuel R. Borstein
Ole Seehausen
Research26 Aug 2020
Nature

Volume: 586, P: 75-79
Excitation mechanism of the mesospheric sodium nightglow

D. R. Herschbach
C. E. Kolb
X. Shi
Research02 Apr 1992
Nature

Volume: 356, P: 414-416
Amplification and altered expression of the c-myc oncogene in A-MuLV-transformed fibroblasts

Alain Nepveu
Paul D. Fahrlander
Kenneth B. Marcu
Research03 Oct 1985
Nature

Volume: 317, P: 440-443
Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation

M. Roussel
S. Saule
D. Stehelin
Research11 Oct 1979
Nature

Volume: 281, P: 452-455
Tightly associated lipids may anchor SV40 large T antigen in plasma membrane

Roland Henning
Jutta Lange-Mutschler
Research20 Oct 1983
Nature

Volume: 305, P: 736-738
Exploitation of the fibrinolytic system by B-cell acute lymphoblastic leukemia and its therapeutic targeting

The fibrinolytic system promotes the progression of solid tumors. Here, the authors show that the fibrinolytic agent plasmin supports B-cell acute lymphoblastic leukemia (B-ALL) progression via remodeling of the extracellular matrix, and the inhibition of plasmin activation with ε-aminocaproic acid prolongs survival in B-ALL mouse models.

Valentina R. Minciacchi
Jimena Bravo
Daniela S. Krause
ResearchOpen Access20 Nov 2024
Nature Communications

Volume: 15, P: 1-19
An intramolecular SH3-domain interaction regulates c-Abl activity

Daniela Barilá
Giulio Superti-Furga
Research01 Mar 1998
Nature Genetics

Volume: 18, P: 280-282
Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape

Witte et al show that previously acquired substitutions in the SARS-CoV-2 spike protein enable the acquisition of new antibody escape substitutions. New and old substitutions interact to enable escape from broadly neutralizing antibodies.

Leander Witte
Viren A. Baharani
Paul D. Bieniasz
ResearchOpen Access19 Jan 2023
Nature Communications

Volume: 14, P: 1-11
X-ray near-field multi-slice ptychography for in-situ imaging

Sina Röper
Karolina Stachnik
Andreas Schropp
ResearchOpen Access01 Sept 2025
Scientific Reports

Volume: 15, P: 1-11
Measurement of the first ionization potential of astatine by laser ionization spectroscopy

The application of astatine, one of the rarest elements on the earth, in the treatment of cancer requires a better understanding of its chemistry. Rothe et al. report the first measurement of the ionization potential of astatine, against which high-level quantum calculations are benchmarked.

S. Rothe
A. N. Andreyev
K. D. A. Wendt
ResearchOpen Access14 May 2013
Nature Communications

Volume: 4, P: 1-6
A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia

Razelle Kurzrock
Mordechai Shtalrid
Jordan U. Gutterman
Research18 Feb 1987
Nature

Volume: 325, P: 631-635
Flight or fight? - How the coronavirus pandemic has affected scientists’ willingness to engage with the public

Frank Marcinkowski
Hella de Haas
Sarah Kohler
ResearchOpen Access13 Jun 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-11
Ia invariant chain detected on lymphocyte surfaces by monoclonal antibody

Norbert Koch
Susanne Koch
Günter J. Hämmerling
Research14 Oct 1982
Nature

Volume: 299, P: 644-645
Enhancing the efficiency of high-order harmonics with two-color non-collinear wave mixing in silica

High-order harmonic generation in solids could develop into a compact, coherent, short-wavelength source. This study shows that two-colour noncollinear wave mixing in silica significantly enhances HHG efficiency over single-color methods, offering a novel pathway for advancing all-solid XUV sources.

Sylvianne D. C. Roscam Abbing
Nataliia Kuzkova
Peter M. Kraus
ResearchOpen Access27 Sept 2024
Nature Communications

Volume: 15, P: 1-7
Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform

Selen Selcen
Lena Wieland
Matthias Wirth
ResearchOpen Access06 Aug 2025
Cell Death Discovery

Volume: 11, P: 1-8
Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups

This study shows how including different ancestry groups in a genome-wide association study for prostate-specific antigen levels can improve prostate cancer risk prediction, with implications for population screening.

Thomas J. Hoffmann
Rebecca E. Graff
John S. Witte
ResearchOpen Access10 Feb 2025
Nature Genetics

Volume: 57, P: 334-344
Differential expression of myc family genes during murine development

Kathryn A. Zimmerman
George D. Yancopoulos
Frederick W. Alt
Research27 Feb 1986
Nature

Volume: 319, P: 780-783
General method for classification of fiber families in fiber-reinforced materials: application to in-vivo human skin images

Maximilian Witte
Sören Jaspers
Frank Fischer
ResearchOpen Access02 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Inflation in the Universe

John D. Barrow
Michael S. Turner
Research02 Jul 1981
Nature

Volume: 292, P: 35-38
The observation of vibrating pear-shapes in radon nuclei

Octupole deformation in nuclei is important to understand nuclear structure and electric dipole moments of heavy atoms. Here the authors measure energies of excited quantum states in radon isotopes and find that these isotopes do not provide favourable conditions in the search for CP-violation.

P. A. Butler
L. P. Gaffney
M. Zielinska
ResearchOpen Access06 Jun 2019
Nature Communications

Volume: 10, P: 1-6
Wave Functions of the Conduction Electrons in Crystalline Aluminium

E. H. MEDLIN
R. E. DINGLE
D. W. FIELD
Research08 Nov 1969
Nature

Volume: 224, P: 581-583
Diminished in vitro tyrosine kinase activity of the EGF receptor of senescent human fibroblasts

Cathleen R. Carlin
Paul D. Phillips
Vincent J. Cristofalo
Research08 Dec 1983
Nature

Volume: 306, P: 617-620
HiBC: a publicly available collection of bacterial strains isolated from the human gut

Here, the authors present and characterise a collection of human gut bacteria including novel taxa associated with health conditions and a large diversity of plasmids. All isolates, their genomes and metadata are publicly available, facilitating research by others (www.hibc.rwth-aachen.de).

Thomas C. A. Hitch
Johannes M. Masson
Thomas Clavel
ResearchOpen Access06 May 2025
Nature Communications

Volume: 16, P: 1-20
p210 Bcr–Abl expression in a primitive multipotent haematopoietic cell line models the development of chronic myeloid leukaemia

Andrew Pierce
P Jane Owen-Lynch
Anthony D Whetton
Research10 Aug 1998
Oncogene

Volume: 17, P: 667-672
Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes

Richard D. Palmiter
Ralph L. Brinster
Ronald M. Evans
Research16 Dec 1982
Nature

Volume: 300, P: 611-615
Peptide containing the BCR oligomerization domain (AA 1-160) reverses the transformed phenotype of p210^bcr–abl positive 32D myeloid leukemia cells

Xiang-Yang D Guo
Jean-Marie Cuillerot
Albert B Deisseroth
Research18 Aug 1998
Oncogene

Volume: 17, P: 825-833
Activation of p65 NF-κB protein by p210^{BCR – ABL} in a myeloid cell line (P210^{BCR – ABL} activates p65 NF-κB)

Malika Hamdane
Marie-Helene David-Cordonnier
Jean Claude D'Halluin
Research06 Nov 1997
Oncogene

Volume: 15, P: 2267-2275
Organolead in wine

R. Lobiński
C. Witte
C.F. Boutron
Research07 Jul 1994
Nature

Volume: 370, P: 24
Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice

A multi-omics approach reveals host–microbiome interactions in aging in mice.

Lena Best
Thomas Dost
Christoph Kaleta
ResearchOpen Access26 Mar 2025
Nature Microbiology

Volume: 10, P: 973-991
Echocardiographic screening for heart failure and optimization of the care pathway for individuals with pacemakers: a randomized controlled trial

For individuals with pacemakers, a care pathway that includes echocardiographic screening to detect signs of heart failure did not improve cardiac outcomes, but patients flagged as having impaired heart function who were managed by a specialized heart failure clinic benefited, as compared to those managed by primary care physicians.

Maria F. Paton
John Gierula
Klaus K. Witte
ResearchOpen Access19 Sept 2024
Nature Medicine

Volume: 30, P: 3303-3309
Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations

Edward Arnold
Alfredo Jacobo-Molina
Stephen H. Hughes
Research07 May 1992
Nature

Volume: 357, P: 85-89
Parvalbumin- and vasoactive intestinal polypeptide-expressing neocortical interneurons impose differential inhibition on Martinotti cells

Martinotti cells disinhibit excitatory cells in the brain cortex and play an important role in information flow. Here the authors study the role of parvalbumin and vasoactive intestinal polypeptide interneurons on the inhibition of Martinotti cells in the mouse somatosensory cortex.

F. Walker
M. Möck
M. Witte
ResearchOpen Access29 Nov 2016
Nature Communications

Volume: 7, P: 1-8
Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice

Here the authors show that lowering IGF-1R levels in endothelial cells improves insulin sensitivity, boosts energy use, and supports beneficial changes in adipose tissue, offering insights into potential treatments for obesity-related metabolic disorders.

Cheukyau Luk
Katherine I. Bridge
Natalie J. Haywood
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-15
Selectivity of MHC-encoded peptide transporters from human, mouse and rat

Frank Momburg
Joost Roelse
Jacques J. Neefjes
Research17 Feb 1994
Nature

Volume: 367, P: 648-651
Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis

The sympathetic nervous system has been shown to respond to stress and activate haematopoietic stem cells. Here they show that cholinergic signals in the bone marrow preserve haematopoietic stem cell quiescence and self-renewal under proliferative stress.

Claire Fielding
Andrés García-García
Simón Méndez-Ferrer
ResearchOpen Access27 Jan 2022
Nature Communications

Volume: 13, P: 1-13
Anomalously small magnetic field in the local interstellar cloud

George Gloeckler
L. A. Fisk
Johannes Geiss
Research27 Mar 1997
Nature

Volume: 386, P: 374-377

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