Glucocorticoids, which are released in response to stress, modulate the consolidation, retrieval and extinction of memories. In this Review, de Quervainet al. suggest that, in fear-related disorders such as post-traumatic stress disorder, targeting glucocorticoid signalling to attenuate fear memories has therapeutic potential.
- Dominique de Quervain
- Lars Schwabe
- Benno Roozendaal