Nature Search

The association between deaths from infection and mutations of the BRAF, FBXW7, NRAS and XPO1 genes: a report from the LRF CLL4 trial

Monica Else
Stuart J. Blakemore
Daniel Catovsky
ResearchOpen Access12 Feb 2021
Leukemia

Volume: 35, P: 2563-2569
Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia

Igor Vořechovský
Liping Luo
Martin A.R. Yuille
Research01 Sept 1997
Nature Genetics

Volume: 17, P: 96-99
GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF

H Rozemuller
W Terpstra
ACM Martens
Research08 Dec 1998
Leukemia

Volume: 12, P: 1962-1970
Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization

J Dierlamm
C Rosenberg
A Hagemeijer
Research01 May 1997
Leukemia

Volume: 11, P: 747-758
Clonality analysis of hematopoietic cell lineages in acute myeloid leukemia and translocation (8;21): only myeloid cells are part of the malignant clone

K van Lom
A Hagemeijer
B Löwenberg
Research01 Feb 1997
Leukemia

Volume: 11, P: 202-205
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

The definition of regulatory landscape at chronic lymphocytic leukaemia (CLL) risk loci is limited. Here, the authors perform an epigenomic characterisation of 42 known risk loci in CLL and normal B cells at different developmental stages and show active chromatin and target genes in the risk loci.

Helen E. Speedy
Renée Beekman
José I. Martín-Subero
ResearchOpen Access09 Aug 2019
Nature Communications

Volume: 10, P: 1-9
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia has a hereditary component, much of which remains to be identified. Here, the authors perform a genome-wide association study and find new risk loci for the disease, which are associated with genes involved in immune function.

Philip J. Law
Sonja I. Berndt
Susan Slager
ResearchOpen Access06 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Hypergranular promyelocytic leukemia: correlation between morphology and chromosomal translocations including t(15;17) and t(11;17)

JM Bennett
D Catovsky
CL Willman
Research17 Jul 2000
Leukemia

Volume: 14, P: 1197-1200
Multilineage outgrowth of both malignant and normal hemopoietic progenitor cells from individual chronic myeloid leukemia patients in immunodeficient mice

MMA Verstegen
JJ Cornelissen
AW Wognum
Research16 Apr 1999
Leukemia

Volume: 13, P: 618-628
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

Richard Houlston and colleagues identify common variants at four loci associated with risk of chronic lymphocytic leukemia, including a coding variant in FARP2 on 2q37.3 and a noncoding variant in the region upstream of MYC on 8q24.21.

Dalemari Crowther-Swanepoel
Peter Broderick
Richard S Houlston
Research10 Jan 2010
Nature Genetics

Volume: 42, P: 132-136
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

Richard Houlston and colleagues identify variants at six loci associated with risk of chronic lymphocytic leukemia. These findings confirm that common, low-penetrance susceptibility alleles contribute to this hematological malignancy and provide new insights into disease etiology.

Maria Chiara Di Bernardo
Dalemari Crowther-Swanepoel
Richard S Houlston
Research31 Aug 2008
Nature Genetics

Volume: 40, P: 1204-1210
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia

Richard Houlston and colleagues report results of a genome-wide association study of chronic lymphocytic leukemia. They validate several new susceptibility loci for this disease, including variants near POT1, TERC and TERT.

Helen E Speedy
Maria Chiara Di Bernardo
Richard S Houlston
Research01 Dec 2013
Nature Genetics

Volume: 46, P: 56-60
Combined analysis of IGHV mutations, telomere length and CD49d identifies long-term progression-free survivors in TP53 wild-type CLL treated with FCR-based therapies

Andrea G. S. Pepper
Antonella Zucchetto
Chris Pepper
ResearchOpen Access19 Jun 2021
Leukemia

Volume: 36, P: 271-274
Breakpoints in the ataxia telangiectasia gene arise at the RGYW somatic hypermutation motif

Paul S Bradshaw
Alison Condie
Martin R Yuille
Research24 Jan 2002
Oncogene

Volume: 21, P: 483-487
Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial

Stuart J. Blakemore
Ruth Clifford
Jonathan C. Strefford
ResearchOpen Access03 Feb 2020
Leukemia

Volume: 34, P: 1760-1774
Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

Molly Went
Amit Sud
Richard S. Houlston
ResearchOpen Access21 Dec 2018
Blood Cancer Journal

Volume: 9, P: 1-9
Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci

Philip J. Law
Amit Sud
Richard S. Houlston
ResearchOpen Access23 Jan 2017
Scientific Reports

Volume: 7, P: 1-11
The use of individualized tumor response testing in treatment selection: second randomization results from the LRF CLL4 trial and the predictive value of the test at trial entry

E Matutes
A G Bosanquet
D Catovsky
CorrespondenceOpen Access19 Jul 2012
Leukemia

Volume: 27, P: 507-510

Search

The association between deaths from infection and mutations of the BRAF, FBXW7, NRAS and XPO1 genes: a report from the LRF CLL4 trial

Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia

GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF

Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization

Clonality analysis of hematopoietic cell lineages in acute myeloid leukemia and translocation (8;21): only myeloid cells are part of the malignant clone

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Hypergranular promyelocytic leukemia: correlation between morphology and chromosomal translocations including t(15;17) and t(11;17)

Multilineage outgrowth of both malignant and normal hemopoietic progenitor cells from individual chronic myeloid leukemia patients in immunodeficient mice

Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk

A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia

A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia

Combined analysis of IGHV mutations, telomere length and CD49d identifies long-term progression-free survivors in TP53 wild-type CLL treated with FCR-based therapies

Breakpoints in the ataxia telangiectasia gene arise at the RGYW somatic hypermutation motif

Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial

Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci

The use of individualized tumor response testing in treatment selection: second randomization results from the LRF CLL4 trial and the predictive value of the test at trial entry

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