Nature Search

Construction of Maps from “Odd Bits of Information”

DAVID G. KENDALL
Research21 May 1971
Nature

Volume: 231, P: 158-159
Neutralizing and binding antibodies are a correlate of risk of COVID-19 in the CoVPN 3008 study in people with HIV

Using data from the CoVPN 3008 study, the authors show that the neutralizing antibody correlate of risk holds in people living with HIV. However, the nAb correlate was weaker and shorter-lived in a vaccine-immunity versus hybrid-immunity population.

Nonhlanhla N. Mkhize
Bo Zhang
Peter B. Gilbert
ResearchOpen Access06 Oct 2025
Nature Communications

Volume: 16, P: 1-19
Hydrogen bonding and biological specificity analysed by protein engineering

Alan R. Fersht
Jian-Ping Shi
Greg Winter
Research21 Mar 1985
Nature

Volume: 314, P: 235-238
Interpreting the Cosmic Microwave Background

DAVID LAYZER
Research06 Aug 1966
Nature

Volume: 211, P: 576-577
SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence

Using mouse pancreatic cancer models, Tsanov et al. show that reactivation of SMAD4 at metastatic sites promotes tumor growth in the lung through RUNX1 but restrains metastatic growth through KLF4 in the liver, influenced by organ-specific epigenetic states.

Kaloyan M. Tsanov
Francisco M. Barriga
Scott W. Lowe
ResearchOpen Access25 Sept 2025
Nature Cancer

P: 1-18
Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

David G. Wilkinson
Sangita Bhatt
Robb Krumlauf
Research05 Oct 1989
Nature

Volume: 341, P: 405-409
Stimulation of Insulin Secretion by Theophylline

JOHN R. TURTLE
GEORGE K. LITTLETON
DAVID M. KIPNIS
Research18 Feb 1967
Nature

Volume: 213, P: 727-728
25 years of groundbreaking discoveries with Chandra

The Chandra X-ray Observatory has provided a high-energy view of objects and processes throughout the Universe. This Review discusses many of the key results from Chandra’s 25 years of data.

Patrick Slane
Ákos Bogdán
David Pooley
Reviews10 Oct 2025
Nature Astronomy

P: 1-13
Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer

Using pancreatic organoids and genetic mouse models, Antonucci et al. show that cellular stress activates an NRF2–EZH2 epigenetic axis leading to metabolic reprogramming and subsequent malignant transformation of KRAS-mutant benign lesions.

Laura Antonucci
Na Li
Michael Karin
Research30 Jun 2025
Nature Cancer

Volume: 6, P: 1263-1282
Expression pattern of the mouse T gene and its role in mesoderm formation

David G. Wilkinson
Sangita Bhatt
Bernhard G. Herrmann
Research15 Feb 1990
Nature

Volume: 343, P: 657-659
A non-genotoxic stem cell therapy boosts lymphopoiesis and averts age-related blood diseases in mice

Konturek-Ciesla et al show that low intensity conditioning with antibody mediated haematopoietic stem cell (HSC) depletion coupled to HSC transplantation boosts blood cell and immune cell generation in aging mice, slowing disease. This approach may help treat age-related blood disorders in humans.

Anna Konturek-Ciesla
Qinyu Zhang
David Bryder
ResearchOpen Access02 Jun 2025
Nature Communications

Volume: 16, P: 1-13
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Pancreatic β-cell regeneration in situ by the ALK3 agonist THR-123

Álvarez-Cubela et al. show that a BMP-7-like peptide induces β-cell regeneration and lowers hyperglycemia in diabetic mice, and reveal the transition of ductal cells into insulin-expressing cells. These results have potential therapeutic implications

Silvia Álvarez-Cubela
Isabella D. Altilio
Juan Domínguez-Bendala
ResearchOpen Access03 Jul 2025
Nature Communications

Volume: 16, P: 1-19
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Neurophysiological evidence of human hippocampal longitudinal differentiation in associative memory

This study provides direct neurophysiological evidence from over 30 human subjects showing that the anterior and posterior hippocampus are functionally distinct, with differences in theta activity linked to recollection and novelty processing.

Tung V. To
David X. Wang
Bradley C. Lega
ResearchOpen Access25 Jul 2025
Nature Communications

Volume: 16, P: 1-18
The effect of artificial selection on phenotypic plasticity in maize

Breeding has increased crop productivity, but whether it has also changed phenotypic plasticity is unclear. Here, the authors find maize genomic regions selected for high productivity show reduced contribution to genotype by environment variation and provide evidence for regulatory control of phenotypic stability.

Joseph L. Gage
Diego Jarquin
Natalia de Leon
ResearchOpen Access07 Nov 2017
Nature Communications

Volume: 8, P: 1-11
Improved limits on small-scale anisotropy in cosmic microwave background

Juan M. Uson
David T. Wilkinson
Research29 Nov 1984
Nature

Volume: 312, P: 427-429
Alteration in the penicillin-binding profile of Bacillus megaterium during sporulation

John A. Todd
David J. Ellar
Research16 Dec 1982
Nature

Volume: 300, P: 640-643
Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells

Daniel M. Altmann
Nancy Hogg
David Wilkinson
Research06 Apr 1989
Nature

Volume: 338, P: 512-514
The human impact on North American erosion, sediment transfer, and storage in a geologic context

Human activities have accelerated soil erosion and landscape change in many areas. Here the authors show how rates of erosion, sediment transfer and alluvial sedimentation have increased by an order of magnitude across North America since European colonization, far exceeding the rates expected of natural processes.

David B. Kemp
Peter M. Sadler
Veerle Vanacker
ResearchOpen Access26 Nov 2020
Nature Communications

Volume: 11, P: 1-9
Considering cosmology

David W. Hughes
Books & Arts31 Oct 1991
Nature

Volume: 353, P: 804-805
SU(2) × U(l): A gauge theory of weak interactions?

David Bailin
Norman Dombey
Research01 Jan 1978
Nature

Volume: 271, P: 20-23
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
The triple QSO PG1115 + 08: another probable gravitational lens

Ray J. Weymann
David Latham
J. Anthony Tyson
Research26 Jun 1980
Nature

Volume: 285, P: 641-643
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence

End-stage kidney disease confers a high risk for severe COVID-19 infection. Using an at-risk group (end-stage kidney disease patients with COVID-19), authors using RNA-sequencing of immune cells and plasma proteomic profiling to investigate the host response to viral infection.

Jack S. Gisby
Norzawani B. Buang
James E. Peters
ResearchOpen Access15 Dec 2022
Nature Communications

Volume: 13, P: 1-21
Free precession of neutron stars

David Pines
Jacob Shaham
Research05 Apr 1974
Nature

Volume: 248, P: 483-486
Direct observation of pulsar microstructure

DALE C. FERGUSON
DAVID A. GRAHAM
RICHARD WIELEBINSKI
Research04 Mar 1976
Nature

Volume: 260, P: 25-27
Catalytic Processes and Petroleum

DAVID M. WILSON
Books & Arts10 Oct 1959
Nature

Volume: 184, P: 1090-1091
A distinct Hox code for the branchial region of the vertebrate head

Paul Hunt
Massimo Gulisano
Robb Krumlauf
Research31 Oct 1991
Nature

Volume: 353, P: 861-864
Asymmetric coding of reward prediction errors in human insula and dorsomedial prefrontal cortex

It is unclear how dorsomedial prefrontal cortex and insula represent reward prediction errors. Here, the authors analyze human intracranial data to reveal spatially mixed, asymmetric coding of valence-specific and unsigned reward prediction errors, with insula leading dorsomedial prefrontal cortex.

Colin W. Hoy
David R. Quiroga-Martinez
Robert T. Knight
ResearchOpen Access21 Dec 2023
Nature Communications

Volume: 14, P: 1-14
A data-driven simulation platform to predict cultivars’ performances under uncertain weather conditions

Predicting crop performance in environments with limited field testing is challenging. Here the authors combine field experimental, DNA sequence, and weather data to predict genotypes’ future performance. They demonstrate the potential of this approach on a large dataset of wheat grain yield.

Gustavo de los Campos
Paulino Pérez-Rodríguez
José Crossa
ResearchOpen Access25 Sept 2020
Nature Communications

Volume: 11, P: 1-10
Clinical experience of using integrated whole genome and transcriptome sequencing as a framework for pediatric and adolescent acute myeloid leukemia diagnosis and risk assessment

Rebecca K. Voss
Victor B. Pastor Loyola
Lu Wang
ResearchOpen Access07 Oct 2025
Leukemia

P: 1-11
Collective synthesis of natural products by means of organocascade catalysis

Spencer B. Jones
Bryon Simmons
David W. C. MacMillan
Research13 Jul 2011
Nature

Volume: 475, P: 183-188
Translational genomics of osteoarthritis in 1,962,069 individuals

A genome-wide association study meta-analysis combined with multiomics data of osteoarthritis identifies 700 effector genes as well as biological processes with a convergent involvement of multiple effector genes; 10% of these genes express the target of approved drugs.

Konstantinos Hatzikotoulas
Lorraine Southam
Eleftheria Zeggini
ResearchOpen Access09 Apr 2025
Nature

Volume: 641, P: 1217-1224
Ribosome slowed by mutation to streptomycin resistance

DAVID J. GALAS
ELBERT W. BRANSCOMB
Research12 Aug 1976
Nature

Volume: 262, P: 617-619
Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

David G. Wilkinson
Sangita Bhatt
Patrick Charnay
Research02 Feb 1989
Nature

Volume: 337, P: 461-464
Pial vessels transport of substances from cerebrospinal fluid to blood

EMANUEL LEVIN
FRANCISCO V. SEPULVEDA
DAVID L. YUDILEVICH
Research17 May 1974
Nature

Volume: 249, P: 266-268
A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation

The hepatopancreatic ductal (HPD) system connects both liver and pancreas to the intestine but the molecular details of HPD development are unclear. Here, the authors describe how regionalised Eph/Ephrin signaling regulates HPD morphogenesis by promoting cellular rearrangements leading to an open tube.

M. Ilcim Thestrup
Sara Caviglia
Elke A. Ober
ResearchOpen Access19 Nov 2019
Nature Communications

Volume: 10, P: 1-15
A dominant mutant receptor from Arabidopsis confers ethylene insensitivity in heterologous plants

Jack Q. Wilkinson
Michael B. Lanahan
Harry J. Klee
Research01 May 1997
Nature Biotechnology

Volume: 15, P: 444-447
Giant shells around normal elliptical galaxies

David F. Malin
David Carter
Research26 Jun 1980
Nature

Volume: 285, P: 643-645
Regional trends in mercury distribution across the Great Lakes states, north central USA

Edward A. Nater
David F. Grigal
Research09 Jul 1992
Nature

Volume: 358, P: 139-141
A randomised controlled trial of the effect of automated interactive calling combined with a health risk forecast on frequency and severity of exacerbations of COPD assessed clinically and using EXACT PRO

David MG Halpin
Tish Laing-Morton
Penny Marno
Research17 Jun 2011
Primary Care Respiratory Journal

Volume: 20, P: 324-331
Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

David Sugden
Jiri Vanecek
Wayne B. Anderson
Research28 Mar 1985
Nature

Volume: 314, P: 359-361
Thresholds for adding degraded tropical forest to the conservation estate

An analysis of the impact of logging intensity on biodiversity in tropical forests in Sabah, Malaysia, identifies a threshold of tree biomass removal below which logged forests still have conservation value.

Robert M. Ewers
C. David L. Orme
Cristina Banks-Leite
ResearchOpen Access17 Jul 2024
Nature

Volume: 631, P: 808-813
The promise of gene ablation

Andrew Lumsden
David Wilkinson
News & Views27 Sept 1990
Nature

Volume: 347, P: 335-336
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report

James A.R. Nicoll
David Wilkinson
Roy O. Weller
Research17 Mar 2003
Nature Medicine

Volume: 9, P: 448-452
BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

David E Jensen
Monja Proctor
Frank J Rauscher III
Research10 Mar 1998
Oncogene

Volume: 16, P: 1097-1112
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Hydrostatic locomotion in a limbless tetrapod

James C. O'Reilly
Dale A. Ritter
David R. Carrier
Research20 Mar 1997
Nature

Volume: 386, P: 269-272

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