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Showing 1–3 of 3 results
Advanced filters: Author: David Mayo-Muñoz Clear advanced filters

  • In response to bacterial CRISPR–Cas immunity, phages and plasmids have evolved small non-coding RNA anti-CRISPRs, known as Racrs, that sequester Cas proteins in abberrant complexes and thereby inhibit immunity.

    • Sarah Camara-Wilpert
    • David Mayo-Muñoz
    • Rafael Pinilla-Redondo
    ResearchOpen Access
    Nature
    Volume: 623, P: 601-607

  • The cryo-EM structure of phage φTE is presented, revealing a distinct neck topology, tail sheath baseplate organization and oligomeric state of the tape measure protein. These features suggest a mechanism linking base plate conformational changes to sheath contraction and genome ejection.

    • James Hodgkinson-Bean
    • Rafael Ayala
    • Mihnea Bostina
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • To successfully invade bacteria, bacteriophages and other mobile genetic elements must overcome numerous types of bacterial defence systems. Here, the authors review the discovery and mechanisms of direct inhibitors of bacterial defence systems, as well as their applications in biotechnology.

    • David Mayo-Muñoz
    • Rafael Pinilla-Redondo
    • Peter C. Fineran
    Reviews
    Nature Reviews Genetics
    Volume: 25, P: 237-254