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Showing 101–150 of 153 results

Advanced filters: Author: David Wahl Clear advanced filters

Atmospheric river activity during the late Holocene exceeds modern range of variability in California

Intense rainfall events resulting from strong atmospheric river activity two and three millennia ago exceeded those of the 20th century around Leonard Lake, California, according to a 3,200-year reconstruction of integrated vapor transport derived from sediment geochemical data.

Clarke A. Knight
Lysanna Anderson
David Wahl
ResearchOpen Access25 Apr 2024
Communications Earth & Environment

Volume: 5, P: 1-8
Alternative transcripts in variant interpretation: the potential for missed diagnoses and misdiagnoses

Kelly Schoch
Queenie K.-G. Tan
Vandana Shashi
Research05 May 2020
Genetics in Medicine

Volume: 22, P: 1269-1275
Constitutive membrane association potentiates activation of Bruton tyrosine kinase

Tianjian Li
David J Rawlings
Anne B Satterthwaite
Research18 Sept 1997
Oncogene

Volume: 15, P: 1375-1383
Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations

Lance H. Rodan
Rebecca C. Spillmann
Vandana Shashi
Research23 Jun 2021
Genetics in Medicine

Volume: 23, P: 1922-1932
Cannabis Sativa targets mediobasal hypothalamic neurons to stimulate appetite

Emma C. Wheeler
Pique Choi
Jon F. Davis
ResearchOpen Access27 Dec 2023
Scientific Reports

Volume: 13, P: 1-13
Bi-allelic ATG4D variants are associated with a neurodevelopmental disorder characterized by speech and motor impairment

Marie Morimoto
Vikas Bhambhani
May Christine V. Malicdan
ResearchOpen Access10 Feb 2023
npj Genomic Medicine

Volume: 8, P: 1-16
The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice

David J Curtis
Lorraine Robb
C Glenn Begley
Research11 Dec 1997
Oncogene

Volume: 15, P: 2975-2983
Intravital imaging of hair follicle regeneration in the mouse

This protocol describes the use of two-photon laser-scanning microscopy (TPLSM) to study hair regeneration within a living, uninjured mouse, enabling time-resolved imaging of single hair follicle stem cells.

Cristiana M Pineda
Sangbum Park
Valentina Greco
Protocols25 Jun 2015
Nature Protocols

Volume: 10, P: 1116-1130
Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice

Humanized bone-marrow-ossicle niches are formed in mice via in situ differentiation of bone-marrow-derived mesenchymal stromal cells and can be used for transplantation of normal and malignant human hematopoietic cells.

Andreas Reinisch
David Cruz Hernandez
Ravindra Majeti
Protocols21 Sept 2017
Nature Protocols

Volume: 12, P: 2169-2188
Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats

Pál Pacher
Takahiro Nagayama
David A Kass
Protocols14 Aug 2008
Nature Protocols

Volume: 3, P: 1422-1434
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)

Hatef Darabi
Jonathan Beesley
Alison M. Dunning
ResearchOpen Access07 Sept 2016
Scientific Reports

Volume: 6, P: 1-14
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy

Maria Castedo
Jean-Luc Perfettini
Guido Kroemer
Research29 Mar 2004
Oncogene

Volume: 23, P: 4362-4370
Individual neural transfer function affects the prediction of subjective depth of focus

Alexander Leube
Tim Schilling
Siegfried Wahl
ResearchOpen Access30 Jan 2018
Scientific Reports

Volume: 8, P: 1-8
Future climate risk from compound events

Compound events, events of significant impact that are caused by a combination of processes, are difficult to predict. This Perspective discusses the need for a systematic approach to improve risk assessment of these events.

Jakob Zscheischler
Seth Westra
Xuebin Zhang
Reviews14 May 2018
Nature Climate Change

Volume: 8, P: 469-477
The potential to reduce uncertainty in regional runoff projections from climate models

Model estimates of future hydroclimate are uncertain, especially at the regional scale. This Perspective argues that constraining model runoff and its sensitivity to precipitation and temperature can greatly reduce this uncertainty and improve climate model utility in water resource applications.

Flavio Lehner
Andrew W. Wood
Justin S. Mankin
Reviews26 Nov 2019
Nature Climate Change

Volume: 9, P: 926-933
Thermal optima of cercarial emergence in trematodes from a marine high-temperature ecosystem, the Persian Gulf

Maral Khosravi
Dakeishla M. Díaz-Morales
Jahangir Vajedsamiei
ResearchOpen Access25 Mar 2023
Scientific Reports

Volume: 13, P: 1-10
Dimerization of the 4Ig isoform of B7-H3 in tumor cells mediates enhanced proliferation and tumorigenic signaling

The 4Ig isoform of B7-H3, an immune modulatory protein expressed in tumors, resides in dimeric states with enhanced dimerization-dependent intrinsic signaling and tumorigenic activities, providing a therapeutically-actionable target for intervention.

Margie N. Sutton
Sarah E. Glazer
David Piwnica-Worms
ResearchOpen Access05 Jan 2024
Communications Biology

Volume: 7, P: 1-15
Long-term durability of immune responses to the BNT162b2 and mRNA-1273 vaccines based on dosage, age and sex

Chapin S. Korosec
Suzan Farhang-Sardroodi
Jane M. Heffernan
ResearchOpen Access08 Dec 2022
Scientific Reports

Volume: 12, P: 1-15
Personal radio use and cancer risks among 48,518 British police officers and staff from the Airwave Health Monitoring Study

He Gao
Maria Aresu
Paul Elliott
ResearchOpen Access26 Dec 2018
British Journal of Cancer

Volume: 120, P: 375-378
Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures

Nicholas R. Rydzewski
Erik Peterson
Shuang G. Zhao
ResearchOpen Access21 Sept 2021
npj Genomic Medicine

Volume: 6, P: 1-9
Quantifying macromolecular interactions in living cells using FRET two-hybrid assays

This protocol describes a nondestructive FRET-based assay for measuring protein interactions in cultured cells. The correlation between FRET efficiencies and relative protein concentration can be used to determine relative binding affinities.

Elisabeth S Butz
Manu Ben-Johny
Christian Wahl-Schott
Protocols10 Nov 2016
Nature Protocols

Volume: 11, P: 2470-2498
Continental-scale temperature variability during the past two millennia

Temperature change over the past 2,000 years has shown pronounced regional variability. An assessment of all available continental temperature reconstructions shows a clear twentieth century warming trend, but no evidence of a coherent Little Ice Age or Medieval Warm Period.

Moinuddin Ahmed
Kevin J. Anchukaitis
Eduardo Zorita
Reviews21 Apr 2013
Nature Geoscience

Volume: 6, P: 339-346
Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

Michel Bernier
Dylan Harney
Rafael de Cabo
ResearchOpen Access21 Jul 2020
npj Aging and Mechanisms of Disease

Volume: 6, P: 1-11
PEDIA: prioritization of exome data by image analysis

Tzung-Chien Hsieh
Martin A. Mensah
Peter M. Krawitz
ResearchOpen Access05 Jun 2019
Genetics in Medicine

Volume: 21, P: 2807-2814
The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints

David A Thompson
Glenn Belinsky
Karl Münger
Research18 Dec 1997
Oncogene

Volume: 15, P: 3025-3035
Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation

Michael F Reed
Vivian F Liu
Mark E Ewen
Research09 Dec 1998
Oncogene

Volume: 17, P: 2961-2971
p53-induced apoptosis in the human T-ALL cell line CCRF-CEM

Stephan Geley
Bernd L Hartmann
Reinhard Kofler
Research13 Nov 1997
Oncogene

Volume: 15, P: 2429-2437
Perinatal Nitric Oxide Synthase Inhibition Retards Neonatal Growth by Inducing Hypertrophic Pyloric Stenosis in Rats

Cynthia A Voelker
Mark J S Miller
Maria R Pierce
Research01 Nov 1995
Pediatric Research

Volume: 38, P: 768-774
Plasminogen promotes sarcoma growth and suppresses the accumulation of tumor-infiltrating macrophages

Alejandro Curino
David J Mitola
Thomas H Bugge
Research16 Dec 2002
Oncogene

Volume: 21, P: 8830-8842
Schistosomes in the Persian Gulf: novel molecular data, host associations, and life-cycle elucidations

Maral Khosravi
David W. Thieltges
Simona Georgieva
ResearchOpen Access05 Aug 2022
Scientific Reports

Volume: 12, P: 1-12
Health benefits of late-onset metformin treatment every other week in mice

Irene Alfaras
Sarah J. Mitchell
Rafael de Cabo
ResearchOpen Access20 Nov 2017
npj Aging and Mechanisms of Disease

Volume: 3, P: 1-13
Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation

Tracy Criswell
Konstantin Leskov
David A Boothman
Reviews28 Aug 2003
Oncogene

Volume: 22, P: 5813-5827
Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression

David N Reisman
Matthew W Strobeck
Bernard E Weissman
Research20 Feb 2002
Oncogene

Volume: 21, P: 1196-1207
p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells

Nathalie Sphyris
David J Harrison
Research14 Feb 2005
Oncogene

Volume: 24, P: 2184-2194
p14ARF is a component of the p53 response following ionizing irradiation of normal human fibroblasts

Shireen Khan
Claudia Guevara
David Parry
Research14 Jun 2004
Oncogene

Volume: 23, P: 6040-6046
A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases

Jennifer E. Kyle
Kelly G. Stratton
Thomas O. Metz
ResearchOpen Access21 Apr 2021
Scientific Data

Volume: 8, P: 1-12
A bacterial pathogen uses dimethylsulfoniopropionate as a cue to target heat-stressed corals

Melissa Garren
Kwangmin Son
Roman Stocker
Research12 Dec 2013
The ISME Journal

Volume: 8, P: 999-1007
Prognostic significance of PET assessment of metabolic response to therapy in oesophageal squamous cell carcinoma

Arpit Chhabra
Leonard T Ong
Karyn A Goodman
ResearchOpen Access10 Dec 2015
British Journal of Cancer

Volume: 113, P: 1658-1665
Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G₁arrest associated with induction of p16ink4a and activation of RB

Bryan L Betz
Matthew W Strobeck
Bernard E Weissman
Research02 Aug 2002
Oncogene

Volume: 21, P: 5193-5203
The National Institutes of Health Undiagnosed Diseases Program: insights into rare diseases

William A. Gahl
Thomas C. Markello
David Adams
Research26 Sept 2011
Genetics in Medicine

Volume: 14, P: 51-59
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency

William P. Bone
Nicole L. Washington
Damian Smedley
ResearchOpen Access12 Nov 2015
Genetics in Medicine

Volume: 18, P: 608-617
A global multiproxy database for temperature reconstructions of the Common Era

Julien Emile-Geay
Nicholas P. McKay
Jens Zinke
ResearchOpen Access11 Jul 2017
Scientific Data

Volume: 4, P: 1-33
One is the loneliest number: genotypic matchmaking using the electronic health record

Elly Brokamp
Mary E. Koziura
Jimann Shin
Comments & Opinion06 Jul 2021
Genetics in Medicine

Volume: 23, P: 1830-1832
Correction to: An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids

Sacha Ferdinandusse
Kirsty McWalter
Frédéric M. Vaz
Amendments and CorrectionsOpen Access19 Oct 2021
Genetics in Medicine

Volume: 23, P: 2467
A global database of Holocene paleotemperature records

Darrell Kaufman
Nicholas McKay
Snezhana Zhilich
ResearchOpen Access14 Apr 2020
Scientific Data

Volume: 7, P: 1-34
Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton

Wei Li
Jianhua Fan
David T Woodley
Reviews17 Oct 2001
Oncogene

Volume: 20, P: 6403-6417
Inactivating intracellular antiviral responses during adenovirus infection

Matthew D Weitzman
David A Ornelles
Reviews21 Nov 2005
Oncogene

Volume: 24, P: 7686-7696
The implications of familial incidental findings from exome sequencing: the NIH Undiagnosed Diseases Program experience

Lauren Lawrence
Murat Sincan
Cornelius F. Boerkoel
Research01 May 2014
Genetics in Medicine

Volume: 16, P: 741-750
Correction: Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations

Lance H. Rodan
Rebecca C. Spillmann
Vandana Shashi
Amendments and Corrections14 Sept 2021
Genetics in Medicine

Volume: 23, P: 2016
Publisher Correction: A global database of Holocene paleotemperature records

Darrell Kaufman
Nicholas McKay
Snezhana Zhilich
Amendments and CorrectionsOpen Access15 Jun 2020
Scientific Data

Volume: 7, P: 1

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