Nature Search

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Large genome-wide meta-analysis of clinically diagnosed late-onset Alzheimer’s disease (LOAD) from 94,437 individuals identifies new LOAD risk loci and implicates Aβ formation, tau protein binding, immune response and lipid metabolism.

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Research28 Feb 2019
Nature Genetics

Volume: 51, P: 414-430
PD-L1⁺ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

Sepsis induces a period of immunosuppression which can be problematic in the face of subsequent infectious challenge. Here the authors show the presence of PD-L1 expressing regulatory plasma cells that can inhibit T cells in a murine model and in patients with sepsis.

Morgane Gossez
Clara Vigneron
Fabienne Venet
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-17
The RARα-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain

Delphine Sitterlin
Pierre Tiollais
Catherine Transy
Research06 Mar 1997
Oncogene

Volume: 14, P: 1067-1074
Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

Aymeric Lanore
Christelle Tesson
Eva Camgrand
ResearchOpen Access02 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-14
ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia

Mariana Tannoury
Marianne Ayoub
Santos A. Susin
Research06 Dec 2023
Leukemia

Volume: 38, P: 302-317
Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system

Delphine Garnier
Ruoya Li
Tuan Huy Nguyen
ResearchOpen Access29 May 2018
Scientific Reports

Volume: 8, P: 1-10
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Amendments and Corrections15 Aug 2019
Nature Genetics

Volume: 51, P: 1423-1424
del(8p) and TNFRSF10B loss are associated with a poor prognosis and resistance to fludarabine in chronic lymphocytic leukemia

Ludovic Jondreville
Lea Dehgane
Florence Nguyen-Khac
Research26 Sept 2023
Leukemia

Volume: 37, P: 2221-2230
Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells

Nina Guyon
Delphine Garnier
Pierre-François Cartron
ResearchOpen Access11 Dec 2020
Cell Death & Disease

Volume: 11, P: 1-11
Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition

Clare E. Weeden
Casey Ah-Cann
Marie-Liesse Asselin-Labat
Research10 May 2018
Oncogene

Volume: 37, P: 4475-4488
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles

Fabio Alexis Lefebvre
Louis Philip Benoit Bouvrette
Éric Lécuyer
ResearchOpen Access10 Jun 2016
Scientific Reports

Volume: 6, P: 1-14
Screening of dementia genes by whole-exome sequencing in early-onset Alzheimer disease: input and lessons

Gaël Nicolas
David Wallon
Didier Hannequin
Research05 Aug 2015
European Journal of Human Genetics

Volume: 24, P: 710-716
A single Proteus mirabilis lineage from human and animal sources: a hidden reservoir of OXA-23 or OXA-58 carbapenemases in Enterobacterales

Rémy A. Bonnin
Delphine Girlich
Thierry Naas
ResearchOpen Access08 Jun 2020
Scientific Reports

Volume: 10, P: 1-9
Post-exposure treatment of non-human primates lethally infected with Ebola virus with EBOTAb, a purified ovine IgG product

Stuart D. Dowall
Frédéric Jacquot
Miles W. Carroll
ResearchOpen Access22 Jun 2017
Scientific Reports

Volume: 7, P: 1-15
Soil organic carbon models need independent time-series validation for reliable prediction

Independent observation-based model validation and improved information flow between predictive and conceptual models are needed to enhance confidence in soil organic carbon predictions, suggests a review of 250 soil organic carbon models.

Julia Le Noë
Stefano Manzoni
Bertrand Guenet
ReviewsOpen Access08 May 2023
Communications Earth & Environment

Volume: 4, P: 1-8

Search

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

PD-L1⁺ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

The RARα-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain

Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis

ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia

Expansion of human primary hepatocytes in vitro through their amplification as liver progenitors in a 3D organoid system

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

del(8p) and TNFRSF10B loss are associated with a poor prognosis and resistance to fludarabine in chronic lymphocytic leukemia

Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells

Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition

Comparative transcriptomic analysis of human and Drosophila extracellular vesicles

Screening of dementia genes by whole-exome sequencing in early-onset Alzheimer disease: input and lessons

A single Proteus mirabilis lineage from human and animal sources: a hidden reservoir of OXA-23 or OXA-58 carbapenemases in Enterobacterales

Post-exposure treatment of non-human primates lethally infected with Ebola virus with EBOTAb, a purified ovine IgG product

Soil organic carbon models need independent time-series validation for reliable prediction

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